日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Multiparameter optimization in CNS drug discovery: design of pyrimido[4,5-d]azepines as potent 5-hydroxytryptamine 2C (5-HT₂C) receptor agonists with exquisite functional selectivity over 5-HT₂A and 5-HT₂B receptors

中枢神经系统药物发现中的多参数优化：设计嘧啶并[4,5-d]氮杂卓类药物作为有效的 5-羟色胺 2C (5-HT₂C) 受体激动剂，对 5-HT₂A 和 5-HT₂B 受体具有精确的功能选择性

期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/jm5003292
R Ian Storer, Paul E Brennan, Alan D Brown, Peter J Bungay, Kelly M Conlon, Matthew S Corbett, Robert P DePianta, Paul V Fish, Alexander Heifetz, Danny K H Ho, Alan S Jessiman, Gordon McMurray, Cesar Augusto F de Oliveira, Lee R Roberts, James A Root, Veerabahu Shanmugasundaram, Michael J Shapiro, M
神经
发表日期：2014
文献求助 收藏

w-REXAMD: A Hamiltonian Replica Exchange Approach to Improve Free Energy Calculations for Systems with Kinetically Trapped Conformations

w-REXAMD：一种用于改进动力学束缚构象体系自由能计算的哈密顿量副本交换方法

期刊:Journal of Chemical Theory and Computation
影响因子:5.5
doi:10.1021/ct300896h
Arrar, Mehrnoosh; de Oliveira, Cesar Augusto F; Fajer, Mikolai; Sinko, William; McCammon, J Andrew
AMD
发表日期：2013
文献求助 收藏

Substrate-dependent dynamics of UDP-galactopyranose mutase: Implications for drug design

UDP-半乳糖吡喃糖变位酶的底物依赖性动力学：对药物设计的启示

期刊:Protein Science
影响因子:5.2
doi:10.1002/pro.2332
Boechi, Leonardo; de Oliveira, Cesar Augusto F; Da Fonseca, Isabel; Kizjakina, Karina; Sobrado, Pablo; Tanner, John J; McCammon, J Andrew
发表日期：2013
文献求助 收藏

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

由MHC呈递的自身肽库改变引起的药物超敏反应

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1207934109
Ostrov, David A; Grant, Barry J; Pompeu, Yuri A; Sidney, John; Harndahl, Mikkel; Southwood, Scott; Oseroff, Carla; Lu, Shun; Jakoncic, Jean; de Oliveira, Cesar Augusto F; Yang, Lun; Mei, Hu; Shi, Leming; Shabanowitz, Jeffrey; English, A Michelle; Wriston, Amanda; Lucas, Andrew; Phillips, Elizabeth; Mallal, Simon; Grey, Howard M; Sette, Alessandro; Hunt, Donald F; Buus, Soren; Peters, Bjoern
发表日期：2012
文献求助 收藏