日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

A Biomimetic Buffering Hydrogel Scaffold for Long-Term Culture of Patient-Derived Tumor Organoids

用于长期培养患者来源肿瘤类器官的仿生缓冲水凝胶支架

期刊:Advanced Healthcare Materials
影响因子:9.6
doi:10.1002/adhm.202504669
Gusarova, Elizaveta; Ahmadi, Fatemeh; Cruickshank, Jennifer; Miao, Zheyuan; Moshkova, Mariia; Pilipenko, Iuliia; Cescon, David W; Kumacheva, Eugenia
3D/类器官
肿瘤
肿瘤免疫
发表日期：2026
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Genome-Wide CRISPR Screens Identify ABCG2-Mediated Drug Resistance to the Threonine Tyrosine Kinase (TTK) Inhibitor CFI-402257 in Breast Cancer

全基因组 CRISPR 筛选发现乳腺癌中 ABCG2 介导的对苏氨酸酪氨酸激酶 (TTK) 抑制剂 CFI-402257 的耐药性

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms27062665
Thu, Kelsie L; Jafari, Soode; Silvester, Jennifer; Cruickshank, Jennifer; Soria-Bretones, Isabel; Hodgson, Kelsey; Tobin, Chantal; Haight, Jillian; Lau, Asa P Y; Bray, Tessa; Wakeham, Drew; Bray, Mark R; Mak, Tak W; Cescon, David W
ABCG2
肿瘤
肿瘤免疫
信号转导
乳腺癌
TTK
发表日期：2026
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Guidance for Canadian Breast Cancer Practice: National Consensus Recommendations for the Systemic Treatment of Patients with HER2+ Breast Cancer in Both the Early and Metastatic Settings (2025 Update)

加拿大乳腺癌诊疗指南：HER2+乳腺癌早期和转移期患者系统治疗的国家共识建议（2025年更新）

期刊:Current Oncology
影响因子:3.4
doi:10.3390/curroncol33040200
Kumar, Aalok; Jerzak, Katarzyna J; Gelmon, Karen A; Boileau, Jean-François; Bouganim, Nathaniel; Brezden-Masley, Christine; Cao, Jeffrey Q; Cescon, David W; Chia, Stephen; Edwards, Scott; Joy, Anil Abraham; Laing, Kara; LeVasseur, Nathalie; Sehdev, Sandeep; Simmons, Christine; Webster, Marc; Manna, Mita; On Behalf Of Patient Advocacy Breast Cancer Canada
肿瘤
乳腺癌
肿瘤免疫
HER2
发表日期：2026
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Guidance for Canadian Breast Cancer Practice: National Consensus Recommendations for the Systemic Treatment of Patients with HR+/HER2- Metastatic Breast Cancer 2025

加拿大乳腺癌诊疗指南：2025年HR+/HER2-转移性乳腺癌患者系统治疗国家共识建议

期刊:Current Oncology
影响因子:3.4
doi:10.3390/curroncol33020106
Jerzak, Katarzyna J; Kumar, Aalok; Boileau, Jean-François; Bouganim, Nathaniel; Brezden-Masley, Christine; Cao, Jeffrey Q; Cescon, David W; Chia, Stephen; Edwards, Scott; Joy, Anil Abraham; Laing, Kara; LeVasseur, Nathalie; Lupichuk, Sasha; Sehdev, Sandeep; Simmons, Christine; Webster, Marc; Gelmon, Karen A; Manna, Mita; On Behalf Of Patient Advocacy Breast Cancer Canada
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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Guidance for Canadian Breast Cancer Practice: National Consensus Recommendations for the Systemic Treatment of Patients with HR+/HER2- Early Breast Cancer 2025

加拿大乳腺癌诊疗指南：2025年HR+/HER2-早期乳腺癌患者系统治疗国家共识建议

期刊:Current Oncology
影响因子:3.4
doi:10.3390/curroncol33020112
Sehdev, Sandeep; Joy, Anil Abraham; Boileau, Jean-François; Bouganim, Nathaniel; Brezden-Masley, Christine; Cao, Jeffrey Q; Cescon, David W; Chia, Stephen; Edwards, Scott; Gelmon, Karen A; Jerzak, Katarzyna J; Kumar, Aalok; Laing, Kara; LeVasseur, Nathalie; Simmons, Christine; Webster, Marc; Manna, Mita; On Behalf Of Patient Advocacy Breast Cancer Canada
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2026
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Pembrolizumab and chemotherapy in high-risk, early-stage, ER(+)/HER2(-) breast cancer: a randomized phase 3 trial

帕博利珠单抗联合化疗治疗高危早期ER(+)/HER2(-)乳腺癌：一项随机3期试验

期刊:Nature Medicine
影响因子:50
doi:10.1038/s41591-024-03415-7
Cardoso, Fatima; O'Shaughnessy, Joyce; Liu, Zhenzhen; McArthur, Heather; Schmid, Peter; Cortes, Javier; Harbeck, Nadia; Telli, Melinda L; Cescon, David W; Fasching, Peter A; Shao, Zhimin; Loirat, Delphine; Park, Yeon Hee; Fernandez, Manuel Gonzalez; Rubovszky, Gábor; Spring, Laura; Im, Seock-Ah; Hui, Rina; Takano, Toshimi; André, Fabrice; Yasojima, Hiroyuki; Ding, Yu; Jia, Liyi; Karantza, Vassiliki; Tryfonidis, Konstantinos; Bardia, Aditya
HER2
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor-Positive Human Epidermal Growth Factor Receptor 2-Negative Breast Cancer: Primary Results From TROPION-Breast01

达托泊单抗德鲁替康对比化疗治疗既往接受过治疗的不可手术/转移性激素受体阳性、人表皮生长因子受体2阴性乳腺癌：TROPION-Breast01研究的主要结果

期刊:Journal of Clinical Oncology
影响因子:41.9
doi:10.1200/JCO.24.00920
Bardia, Aditya; Jhaveri, Komal; Im, Seock-Ah; Pernas, Sonia; De Laurentiis, Michelino; Wang, Shusen; Martínez Jañez, Noelia; Borges, Giuliano; Cescon, David W; Hattori, Masaya; Lu, Yen-Shen; Hamilton, Erika; Zhang, Qingyuan; Tsurutani, Junji; Kalinsky, Kevin; Rubini Liedke, Pedro Emanuel; Xu, Lu; Fairhurst, Rick M; Khan, Sabrina; Denduluri, Neelima; Rugo, Hope S; Xu, Binghe; Pistilli, Barbara
肿瘤
肿瘤免疫
信号转导
乳腺癌
Human
免疫/内分泌
发表日期：2025
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Longitudinal evaluation of circulating tumor DNA in patients undergoing neoadjuvant therapy for early breast cancer using a tumor-informed assay

利用肿瘤信息检测方法对接受早期乳腺癌新辅助治疗的患者循环肿瘤DNA进行纵向评估

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-56658-4
Elliott, Mitchell J; Echelard, Philippe; Pipinikas, Christodoulos; Main, Sasha; Fuentes Antrás, Jesús; Dou, Aaron; Veitch, Zachary; Amir, Eitan; Nadler, Michelle B; Meti, Nicholas; Atenafu, Eshetu; Shah, Elizabeth; Yu, Celeste; Campbell, Nathan; Ventura, Robert; Siu, Lillian L; Bedard, Philippe L; Berman, Hal K; Cescon, David W
肿瘤
乳腺癌
肿瘤免疫
发表日期：2025
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Machine learning-assisted exploration of multidrug-drug administration regimens for organoid arrays

利用机器学习辅助探索类器官阵列的多药联合给药方案

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adt1851
Yakavets, Ilya; Kheiri, Sina; Cruickshank, Jennifer; Hickman, Riley J; Rakhshani, Faeze; Aldeghi, Matteo; Rajaonson, Ella M; Young, Edmond W K; Aspuru-Guzik, Alán; Cescon, David W; Kumacheva, Eugenia
3D/类器官
发表日期：2025
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Ultrasensitive Detection and Monitoring of Circulating Tumor DNA Using Structural Variants in Early-Stage Breast Cancer

利用结构变异对早期乳腺癌循环肿瘤DNA进行超灵敏检测和监测

期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-24-3472
Elliott, Mitchell J; Howarth, Karen; Main, Sasha; Fuentes Antrás, Jesús; Echelard, Philippe; Dou, Aaron; Amir, Eitan; Nadler, Michelle B; Shah, Elizabeth; Yu, Celeste; Bratman, Scott; Bird, Taylor; Roh, June; de Bruin, Elza C; Rushton, Christopher; Chen, Yilun; Gladchuk, Sergii; George, Anthony M; Birkeälv, Sofia; Alcaide, Miguel; Oton, Lucia; Putcha, Girish; Woodhouse, Samuel; Bedard, Philippe L; Siu, Lillian L; Berman, Hal K; Cescon, David W
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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