日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

CD33 epitope editing unlocks UM171-expanded cord blood grafts for AML immunotherapy

CD33表位编辑技术使UM171扩增的脐带血移植可用于急性髓系白血病免疫治疗。

Lehnertz, Bernhard; Langouët, Maéva; Corneau, Sophie; MacRae, Tara; Joe, Maju; Schmidt, Edward N; Spinella, Jean-Francois; Mayotte, Nadine; Moore, Susan; Tellechea, Maria Florencia; Boivin, Isabel; Papineau, Loïc; Rojas-Sutterlin, Shanti; Tual, Margaux; Cortes, Camille Jimenez; Chagraoui, Jalila; Tomellini, Elisa; Desse, Virginie; Gagnon, Etienne; Macauley, Matthew S; Sauvageau, Guy

Deciphering the effect of UM171 on human hematopoietic progenitor cell fate through clonal analysis

通过克隆分析解析UM171对人类造血祖细胞命运的影响

Patrick Coulombe ,Elisa Tomellini ,Jalila Chagraoui ,Nadine Mayotte ,Guy Sauvageau

CoREST in pieces: Dismantling the CoREST complex for cancer therapy and beyond

CoREST 系统拆解:CoREST 复合物在癌症治疗及其他领域的应用研究

Ismail, Houssam; Chagraoui, Jalila; Sauvageau, Guy

IL1RAP is an immunotherapeutic target for normal karyotype triple-mutated acute myeloid leukemia.

IL1RAP 是正常核型三突变急性髓系白血病的免疫治疗靶点

Métois Arnaud, Bordeleau Marie-Eve, Theret Louis, Hajmirza Azadeh, Moujaber Ossama, Spinella Jean-François, Chagraoui Jalila, Mayotte Nadine, Boivin Isabel, Audemard Éric, Aubert Léo, Lisi Véronique, Khakipoor Banafsheh, Farah Azer, Bonneil Éric, Robert Alma, Lippens Julie, Moraitis Anna, Béliveau François, Feghaly Albert, Boucher Geneviève, Marcotte Richard, Gendron Patrick, Thibault Pierre, Lemieux Sébastien, Richard-Carpentier Guillaume, Lavallée Vincent-Philippe, Hébert Josée, Roux Philippe P, Sauvageau Guy

5-HT6 receptors: Contemporary views on their neurobiological and pharmacological relevance in neuropsychiatric disorders

5-HT6受体:关于其在神经精神疾病中的神经生物学和药理学意义的最新观点

Chagraoui, Abdeslam; Thibaut, Florence; De Deurwaerdère, Philippe

DDB1 engagement defines the selectivity of S656 analogs for cyclin K degradation over CDK inhibition.

DDB1 的参与决定了 S656 类似物对细胞周期蛋白 K 降解的选择性,而非对 CDK 的抑制

Moison Céline, Mendoza-Sanchez Rodrigo, Gracias Deanne, Schuetz Doris A, Spinella Jean-François, Girard Simon, Thavonekham Bounkham, Chagraoui Jalila, Durand Aurélie, Fortier Simon, MacRae Tara, Bonneil Eric, Rose Yannick, Mayotte Nadine, Boivin Isabel, Thibault Pierre, Hébert Josée, Ruel Réjean, Marinier Anne, Sauvageau Guy

Widespread and Heterologous Effects of L-DOPA on Monoaminergic Tissue Metabolism in Newborn Rats Expressing Air-Stepping.

左旋多巴对表现出空中踏步行为的新生大鼠单胺能组织代谢的广泛和异质性影响

Barrière Grégory, Pelloquin-Mvogo Zora, Boulain Marie, Khsime Inès, Bharatiya Rahul, Riquier Marie-Anne, Morin Didier, Allain Anne-Emilie, Chagraoui Abdeslam, Juvin Laurent, De Deurwaerdere Philippe

DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML

DELE1 单倍体不足导致 5 号单体性 / del(5q) AML 对线粒体应激诱导的细胞凋亡产生抵抗

Jean-François Spinella, Jalila Chagraoui, Céline Moison, Vincent P Lavallée, Isabel Boivin, Deanne Gracias, Sylvie Lavallée, Guillaume Richard Carpentier, François Beliveau, Josée Hébert #, Guy Sauvageau #

CBFA2T3::GLIS2 pediatric acute megakaryoblastic leukemia is sensitive to BCL-XL inhibition by navitoclax and DT2216

CBFA2T3::GLIS2 儿童急性巨核细胞白血病对 navitoclax 和 DT2216 的 BCL-XL 抑制敏感

Verena Gress, Mathieu Roussy, Luc Boulianne, Mélanie Bilodeau, Sophie Cardin, Nehme El-Hachem, Véronique Lisi, Banafsheh Khakipoor, Alexandre Rouette, Azer Farah, Louis Théret, Léo Aubert, Furat Fatima, Éric Audemard, Pierre Thibault, Éric Bonneil, Jalila Chagraoui, Louise Laramée, Patrick Gendron, 

Towards clinically meaningful expansion of human HSCs

迈向具有临床意义的人类造血干细胞扩增

Tellechea, Maria Florencia; Chagraoui, Jalila; Cohen, Sandra; Sauvageau, Guy