Piperine Induces Apoptosis and Cell Cycle Arrest via Multiple Oxidative Stress Mechanisms and Regulation of PI3K/Akt and MAPK Signaling in Colorectal Cancer Cells
胡椒碱通过多种氧化应激机制以及对PI3K/Akt和MAPK信号通路的调控,诱导结直肠癌细胞凋亡和细胞周期阻滞。
期刊:Antioxidants
影响因子:6.6
doi:10.3390/antiox14070892
Chang, Wan-Ling; Peng, Jyun-Yu; Hong, Chain-Lang; Li, Pei-Ching; Chye, Soi Moi; Lu, Fung-Jou; Lin, Huei-Yu; Chen, Ching-Hsein
肿瘤
肠癌
表观遗传
肿瘤免疫
凋亡
氧化应激
信号转导
Apoptosis
PI3K/Akt
MAPK/ERK
细胞生物学
毒理研究