日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

3,4-Dimethoxychalcone-induced caloric restriction inhibits PANoptosis to promote ischemic and diabetic skin flap survival: experimental studies

3,4-二甲氧基查尔酮诱导的热量限制抑制PANoptosis,从而促进缺血性和糖尿病性皮瓣存活:实验研究

Yu, Gaoxiang; Zhao, Jiayi; Zhu, Xuwei; Yang, Ningning; Lou, Junsheng; Chen, Zhuliu; Zhang, Haojie; Chaire, Tafadzwa; Gao, Weiyang; Cai, Yuepiao; Wang, Xiangyang; Ding, Jian; Xiao, Jian; Zhou, Kailiang; Qi, Jianjun

Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction.

双重抑制 BET 和 EP300 对未分化多形性肉瘤具有抗肿瘤活性,并与铁死亡诱导产生协同作用

Verbeke Stéphanie, Bourdon Aurélien, Lafon Mathilde, Chaire Vanessa, Frederic Bertolo, Naït Eldjoudi Amina, Derieppe Marie-Alix, Giles Francis, Italiano Antoine

Deciphering the correlation between metabolic activity through 18F-FDG-PET/CT and immune landscape in soft-tissue sarcomas: an insight from the NEOSARCOMICS study

通过 18F-FDG-PET/CT 解读软组织肉瘤代谢活性与免疫图谱之间的相关性:来自 NEOSARCOMICS 研究的启示

Crombé, Amandine; Bertolo, Frédéric; Vanhersecke, Lucile; Guegan, Jean-Philippe; Bessede, Alban; Perret, Raul; Le Loarer, François; Chaire, Vanessa; Coindre, Jean-Michel; Lucchesi, Carlo; Italiano, Antoine

Integration of pre-treatment computational radiomics, deep radiomics, and transcriptomics enhances soft-tissue sarcoma patient prognosis

整合治疗前计算放射组学、深部放射组学和转录组学可提高软组织肉瘤患者的预后。

Crombé, Amandine; Lucchesi, Carlo; Bertolo, Frédéric; Kind, Michèle; Spalato-Ceruso, Mariella; Toulmonde, Maud; Chaire, Vanessa; Michot, Audrey; Coindre, Jean-Michel; Perret, Raul; Le Loarer, François; Bourdon, Aurélien; Italiano, Antoine

Genome-wide CRISPR/Cas9 library screening identified ATM signaling network genes as critical drivers for resistance to ATR inhibition in soft-tissue sarcomas: synthetic lethality and therapeutic implications

全基因组 CRISPR/Cas9 文库筛选发现 ATM 信号通路基因是软组织肉瘤中 ATR 抑制剂耐药的关键驱动因素:合成致死性和治疗意义

Spalato-Ceruso, M; Laroche-Clary, A; Perret, R; Valverde, Y; Chaire, V; Derieppe, Marie-Alix; Velasco, V; Bourdon, A; Italiano, A

Antitumor Effects of PRMT5 Inhibition in Sarcomas

PRMT5 抑制对肉瘤的抗肿瘤作用

Stéphanie Verbeke, Aurélien Bourdon, Jean-Philippe Guegan, Laura Leroy, Vanessa Chaire, Elodie Richard, Alban Bessede, Antoine Italiano

GSK3-beta as a candidate therapeutic target in soft tissue sarcomas

GSK3-β作为软组织肉瘤的潜在治疗靶点

Verbeke, S; Perret, R; Chaire, V; Richard, E; Velasco, V; Giles, F; Cavalcante, L; Italiano, A

High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

未分化多形性肉瘤的高通量分析确定了两个主要亚组,它们具有不同的免疫特征、临床结果和对靶向治疗的敏感性

Maud Toulmonde, Carlo Lucchesi, Stéphanie Verbeke, Amandine Crombe, Julien Adam, Damien Geneste, Vanessa Chaire, Audrey Laroche-Clary, Raul Perret, François Bertucci, Frederic Bertolo, Laurence Bianchini, Bérengère Dadone-Montaudie, Todd Hembrough, Steve Sweet, Yeoun Jin Kim, Fabiola Cecchi, Françoi

ATR Inhibition Broadly Sensitizes Soft-Tissue Sarcoma Cells to Chemotherapy Independent of Alternative Lengthening Telomere (ALT) Status

ATR 抑制可广泛增强软组织肉瘤细胞对化疗的敏感性,且与替代延长端粒 (ALT) 状态无关

Audrey Laroche-Clary, Vanessa Chaire, Stéphanie Verbeke, Marie-Paule Algéo, Andrei Malykh, François Le Loarer, Antoine Italiano

Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting

去分化脂肪肉瘤的全新治疗见解:FGFR 和 MDM2 双重靶向的作用

Bérengère Dadone-Montaudié, Audrey Laroche-Clary, Aline Mongis, Emmanuel Chamorey, Ilaria Di Mauro, Vanessa Chaire, Pascal Finetti, Renaud Schiappa, François Le Loarer, Isabelle Birtwisle-Peyrottes, Jean-François Michiels, François Bertucci, Florence Pedeutour, Antoine Italiano, Laurence Bianchini