日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The development and approval of tecoviromat (TPOXX(®)), the first antiviral against smallpox

特科维罗玛(TPOXX®)的研发和获批,这是首个抗天花病毒药物。

Merchlinsky, Michael; Albright, Andrew; Olson, Victoria; Schiltz, Helen; Merkeley, Tyler; Hughes, Claiborne; Petersen, Brett; Challberg, Mark

Long-Term In Vitro Expansion of Epithelial Stem Cells Enabled by Pharmacological Inhibition of PAK1-ROCK-Myosin II and TGF-β Signaling

通过药理学抑制 PAK1-ROCK-肌球蛋白 II 和 TGF-β 信号传导实现上皮干细胞的长期体外扩增

Chengkang Zhang, Hyung Joo Lee, Anura Shrivastava, Ruipeng Wang, Travis J McQuiston, Sharon S Challberg, Brian A Pollok, Ting Wang

Generation of stable PDX derived cell lines using conditional reprogramming

利用条件重编程生成稳定的PDX衍生细胞系

Borodovsky, Alexandra; McQuiston, Travis J; Stetson, Daniel; Ahmed, Ambar; Whitston, David; Zhang, Jingwen; Grondine, Michael; Lawson, Deborah; Challberg, Sharon S; Zinda, Michael; Pollok, Brian A; Dougherty, Brian A; D'Cruz, Celina M

Host-based antipoxvirus therapeutic strategies: turning the tables

基于宿主的抗痘病毒治疗策略:扭转局面

Fauci, Anthony S; Challberg, Mark D

Inhibition of herpes simplex virus type 1 DNA polymerase activity by peptides from the UL42 accessory protein is largely nonspecific

UL42辅助蛋白肽段对1型单纯疱疹病毒DNA聚合酶活性的抑制作用在很大程度上是非特异性的。

Owsianka, A M; Hart, G; Murphy, M; Gottlieb, J; Boehme, R; Challberg, M; Marsden, H S

Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells

从重组杆状病毒感染的昆虫细胞中纯化的过表达单纯疱疹病毒DNA聚合酶的酶活性

Marcy, A I; Olivo, P D; Challberg, M D; Coen, D M

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

单纯疱疹病毒1型UL42基因产物:DNA聚合酶的一个亚基,其功能是提高DNA聚合酶的持续合成能力。

Gottlieb, J; Marcy, A I; Coen, D M; Challberg, M D

Herpes simplex virus 1 helicase-primase: a complex of three herpes-encoded gene products

单纯疱疹病毒1型解旋酶-引物酶:由三种疱疹病毒编码基因产物组成的复合物

Crute, J J; Tsurumi, T; Zhu, L A; Weller, S K; Olivo, P D; Challberg, M D; Mocarski, E S; Lehman, I R

Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein

单纯疱疹病毒DNA复制:UL9基因编码一种起始点结合蛋白

Olivo, P D; Nelson, N J; Challberg, M D

A method for identifying the viral genes required for herpesvirus DNA replication

一种鉴定疱疹病毒DNA复制所需病毒基因的方法

Challberg, M D