日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Metabolism, Pharmacokinetics, and Tissue Distribution of a Selective FK506-Binding Protein 12 F36V Mutant Degrader in Mice

小鼠体内选择性FK506结合蛋白12 F36V突变降解物的代谢、药代动力学和组织分布

期刊:ACS Pharmacology and Translational Science
影响因子:3.7
doi:10.1021/acsptsci.5c00643
Zhou, Shenzhi; Qin, Xuan; Tran, Kevin; Wang, Jian; Ji, Xingyu; MacKenzie, Kevin R; Chamakuri, Srinivas; Wang, Jin; Li, Feng
代谢
发表日期：2025
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Reversible male contraception by targeted inhibition of serine/threonine kinase 33

通过靶向抑制丝氨酸/苏氨酸激酶33实现可逆性男性避孕

期刊:Science
影响因子:45.8
doi:10.1126/science.adl2688
Ku, Angela F; Sharma, Kiran L; Ta, Hai Minh; Sutton, Courtney M; Bohren, Kurt M; Wang, Yong; Chamakuri, Srinivas; Chen, Ruihong; Hakenjos, John M; Jimmidi, Ravikumar; Kent, Katarzyna; Li, Feng; Li, Jian-Yuan; Ma, Lang; Madasu, Chandrashekhar; Palaniappan, Murugesan; Palmer, Stephen S; Qin, Xuan; Robers, Matthew B; Sankaran, Banumathi; Tan, Zhi; Vasquez, Yasmin M; Wang, Jian; Wilkinson, Jennifer; Yu, Zhifeng; Ye, Qiuji; Young, Damian W; Teng, Mingxing; Kim, Choel; Matzuk, Martin M
信号转导
发表日期：2024
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Discovery of highly potent and ALK2/ALK1 selective kinase inhibitors using DNA-encoded chemistry technology.

利用DNA编码化学技术发现高效且对ALK2/ALK1具有选择性的激酶抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2413108121
Jimmidi Ravikumar, Monsivais Diana, Ta Hai Minh, Sharma Kiran L, Bohren Kurt M, Chamakuri Srinivas, Liao Zian, Li Feng, Hakenjos John M, Li Jian-Yuan, Mishina Yuji, Pan Haichun, Qin Xuan, Robers Matthew B, Sankaran Banumathi, Tan Zhi, Tang Suni, Vasquez Yasmin M, Wilkinson Jennifer, Young Damian W, Palmer Stephen S, MacKenzie Kevin R, Kim Choel, Matzuk Martin M
其它
发表日期：2024
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Expanding Complex Morpholines Using Systematic Chemical Diversity

利用系统化学多样性扩展复杂吗啉

期刊:Organic Letters
影响因子:5
doi:10.1021/acs.orglett.4c00528
Tang, Sunny Ann; Fults, Afton; Boyd, Shelton R; Gattu, Nikhil; Tran, Kevin A; Fan, Jiayi; MacKenzie, Kevin R; Palzkill, Timothy; Young, Damian W; Chamakuri, Srinivas
发表日期：2024
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Chemical Catalysis Guides Structural Identification for the Major In Vivo Metabolite of the BET Inhibitor JQ1

化学催化指导BET抑制剂JQ1主要体内代谢物的结构鉴定

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.3c00464
Holmes, Secondra; Jain, Prashi; Rodriguez, Kenneth Guzman; Williams, Jade; Yu, Zhifeng; Cerda-Smith, Christian; Samuel, Errol L G; Campbell, James; Hakenjos, John Michael; Monsivais, Diana; Li, Feng; Chamakuri, Srinivas; Matzuk, Martin M; Santini, Conrad; MacKenzie, Kevin R; Young, Damian W
代谢
发表日期：2024
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Synthesis and Optimization of Small Molecule Inhibitors of Prostate Specific Antigen

前列腺特异性抗原小分子抑制剂的合成与优化

期刊:ACS Medicinal Chemistry Letters
影响因子:4
doi:10.1021/acsmedchemlett.4c00257
Erickson, Jeffery A; Jimmidi, Ravikumar; Anamthathmakula, Prashanth; Qin, Xuan; Wang, Jian; Gong, Leyi; Park, Jaehyeon; Koolpe, Gary; Tan, Caitlin; Matzuk, Martin M; Li, Feng; Chamakuri, Srinivas; Winuthayanon, Wipawee
发表日期：2024
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Heterocyclic Merging of Stereochemically Diverse Chiral Piperazines and Morpholines with Indazoles

立体化学结构多样的手性哌嗪和吗啉与吲唑的杂环融合

期刊:Chemistry-A European Journal
影响因子:3.7
doi:10.1002/chem.202301888
Viveki, Amol B; Mansfield, Timothy M; Tran, Kevin A; Lenkeit, Evan; MacKenzie, Kevin R; Young, Damian W; Chamakuri, Srinivas
发表日期：2023
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A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines

由1,2-二胺构建3-取代哌嗪-2-乙酸酯的简洁合成方法

期刊:Molecules
影响因子:4.6
doi:10.3390/molecules27113419
Chamakuri, Srinivas; Tang, Sunny Ann; Tran, Kevin A; Guduru, Shiva Krishna Reddy; Bolin, Peter K; MacKenzie, Kevin R; Young, Damian W
发表日期：2022
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DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 M(pro) inhibitors.

DNA编码化学技术可快速获得SARS-CoV-2 M(pro)抑制剂

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2111172118
Chamakuri Srinivas, Lu Shuo, Ucisik Melek Nihan, Bohren Kurt M, Chen Ying-Chu, Du Huang-Chi, Faver John C, Jimmidi Ravikumar, Li Feng, Li Jian-Yuan, Nyshadham Pranavanand, Palmer Stephen S, Pollet Jeroen, Qin Xuan, Ronca Shannon E, Sankaran Banumathi, Sharma Kiran L, Tan Zhi, Versteeg Leroy, Yu Zhifeng, Matzuk Martin M, Palzkill Timothy, Young Damian W
信号转导
新冠
发表日期：2021
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