日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Quantitative analysis of protein lipidation and acyl-CoAs reveals substrate preferences of the S-acylation machinery

对蛋白质脂化和酰基辅酶A的定量分析揭示了S-酰化机制的底物偏好性。

Busquets-Hernández, Carla; Ribó, Silvia; Gratacós-Batlle, Esther; Carbajo, Daniel; Tsiotsia, Alexandra; Blanco-Canosa, Juan B; Chamberlain, Luke H; Triola, Gemma

The Hydrophobic Cysteine-rich Domain of SNAP25 Couples with Downstream Residues to Mediate Membrane Interactions and Recognition by DHHC Palmitoyl Transferases

SNAP25 的疏水性富含半胱氨酸结构域与下游残基结合,介导膜相互作用和 DHHC 棕榈酰转移酶的识别。

Greaves, Jennifer; Prescott, Gerald R; Fukata, Yuko; Fukata, Masaki; Salaun, Christine; Chamberlain, Luke H

Regulatory effects of protein S-acylation on insulin secretion and insulin action

蛋白质S-酰化对胰岛素分泌和胰岛素作用的调节作用

Chamberlain, Luke H; Shipston, Michael J; Gould, Gwyn W

The linker domain of the SNARE protein SNAP25 acts as a flexible molecular spacer that ensures efficient S-acylation.

SNARE 蛋白 SNAP25 的连接域作为灵活的分子间隔物,确保高效的 S-酰化

Salaun Christine, Greaves Jennifer, Tomkinson Nicholas C O, Chamberlain Luke H

Regulatory effects of post-translational modifications on zDHHC S-acyltransferases.

翻译后修饰对 zDHHC S-酰基转移酶的调控作用

Zmuda Filip, Chamberlain Luke H

Identification of key features required for efficient S-acylation and plasma membrane targeting of sprouty-2.

确定 sprouty-2 高效 S-酰化和质膜靶向所需的关键特征

Locatelli Carolina, Lemonidis Kimon, Salaun Christine, Tomkinson Nicholas C O, Chamberlain Luke H

Tracking intracellular uptake and localisation of alkyne tagged fatty acids using Raman spectroscopy

利用拉曼光谱追踪炔基标记脂肪酸的细胞内摄取和定位

Jamieson, Lauren E; Greaves, Jennifer; McLellan, Jayde A; Munro, Kevin R; Tomkinson, Nicholas C O; Chamberlain, Luke H; Faulds, Karen; Graham, Duncan

Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.

通过点击化学揭示了zDHHC家族S-酰基转移酶脂肪酸选择性的分子基础

Greaves Jennifer, Munro Kevin R, Davidson Stuart C, Riviere Matthieu, Wojno Justyna, Smith Terry K, Tomkinson Nicholas C O, Chamberlain Luke H

The C-terminal domain of zDHHC2 contains distinct sorting signals that regulate intracellular localisation in neurons and neuroendocrine cells

zDHHC2 的 C 端结构域包含不同的分选信号,这些信号调控其在神经元和神经内分泌细胞中的细胞内定位。

Salaun, Christine; Ritchie, Louise; Greaves, Jennifer; Bushell, Trevor J; Chamberlain, Luke H

The physiology of protein S-acylation

蛋白质S-酰化作用的生理学

Chamberlain, Luke H; Shipston, Michael J