日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody

利用双表位靶向合成抗体预防致命性犬瘟热病毒感染

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67600-z
Scherer, Melanie; Djabeur, Nadia; Siering, Oliver; Jeckelmann, Jean-Marc; Wyss, Marianne; Cresci, Marina; Di Palma Subran, Morgane; Riedl, Rainer; Chames, Patrick; Pfaller, Christian K; Sawatsky, Bevan; Fotiadis, Dimitrios; Plattet, Philippe
炎症/感染
微生物学
发表日期：2026
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Nanobody-enhanced T cell cancer immunotherapy: Advancing precision medicine

纳米抗体增强型T细胞癌症免疫疗法：推进精准医疗

期刊:Molecular Therapy
影响因子:12
doi:10.1016/j.ymthe.2025.10.043
Boisgard, Remy; Prothon, Juliette; Torrielli, Celia; Chames, Patrick; Kerfelec, Brigitte
肿瘤
T细胞
肿瘤免疫
T细胞
细胞生物学
免疫/内分泌
发表日期：2026
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Mesothelin biology and the evolving landscape of targeted immunotherapy

间皮素生物学及靶向免疫疗法的演变

期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2026.201148
Boisgard, Remy; Chames, Patrick; Kerfelec, Brigitte
免疫/内分泌
发表日期：2026
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Cell-Based Immunization Combined with Single-Round Cell Panning Enables Discovery of PSMA-Targeting Nanobodies from Phage Display Libraries

细胞免疫结合单轮细胞筛选技术，可从噬菌体展示文库中发现靶向PSMA的纳米抗体

期刊:Biomolecules
影响因子:4.8
doi:10.3390/biom16020307
Yang, Tong; Veldhoven-Zweistra, Joke; Ligtenberg, Maarten; Erkens, Sigrun; Berg, Mirella Vredenbregt-van den; Jansen, Rick; Chames, Patrick; Bindels, Eric M J; Ahmadi, Khadijeh; Bangma, Chris H; Kalsbeek, Anton M F; Leivo, Janne; Lumen, Nicolaas; Werken, Harmen J G van de; Weerden, Wytske M van; Kavousipour, Soudabeh; Tooyserkani, Raheleh; Jenster, Guido
细胞生物学
免疫/内分泌
发表日期：2026
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Selection and optimization strategy for Rap1-targeting single-domain antibodies as platelet activation markers

筛选和优化靶向Rap1的单域抗体作为血小板活化标志物的策略

期刊:Research and Practice in Thrombosis and Haemostasis
影响因子:3.4
doi:10.1016/j.rpth.2025.103294
Alessi, Marie-Christine; Moulard, Maxime; Boulay-Moine, Daniele; Pons, Cyril; Margier, Marielle; Vessière, Cléa; Poggi, Marjorie; Pigaglio, Theo; Dignat-George, Francoise; Roussel, Alain; Burtey, Stéphane; Bonello, Laurent; Chames, Patrick; Bonjean, Remi; Peiretti, Franck
血小板
发表日期：2026
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Nanobody therapy rescues behavioural deficits of NMDA receptor hypofunction.

纳米抗体疗法可挽救 NMDA 受体功能低下引起的行为缺陷

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-025-09265-8
Oosterlaken Mathieu, Rogliardo Angelina, Lipina Tatiana, Lafon Pierre-André, Tsitokana Mireille Elodie, Keck Mathilde, Cahuzac Héloïse, Prieu-Sérandon Pierre, Diem Séverine, Derieux Cécile, Camberlin Célia, Lafont Chrystel, Meyer Damien, Chames Patrick, Vandermoere Franck, Marin Philippe, Prézeau Laurent, Servent Denis, Salahpour Ali, Ramsey Amy J, Bécamel Carine, Pin Jean-Philippe, Kniazeff Julie, Rondard Philippe
其它
发表日期：2025
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Nanobody-based canine PD-L1-targeting immune checkpoint inhibitors for cancer therapy in dogs

用于犬类癌症治疗的基于纳米抗体的PD-L1靶向免疫检查点抑制剂

期刊:Molecular Therapy Oncology
影响因子:5.3
doi:10.1016/j.omton.2025.201036
Di Palma Subran, Morgane; Wyss, Marianne; Taskoparan, Betül; Maheswaran, Mathischan; Berg, Johannes Vom; Plattet, Philippe; Chames, Patrick
PD-L1
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2025
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Tissue clearing and 3D reconstruction of digitized, serially sectioned slides provide novel insights into pancreatic cancer

组织透明化和数字化连续切片的三维重建为胰腺癌研究提供了新的视角。

期刊:Med
影响因子:11.8
doi:10.1016/j.medj.2022.11.009
Kiemen, Ashley L; Damanakis, Alexander Ioannis; Braxton, Alicia M; He, Jin; Laheru, Daniel; Fishman, Elliot K; Chames, Patrick; Pérez, Cristina Almagro; Wu, Pei-Hsun; Wirtz, Denis; Wood, Laura D; Hruban, Ralph H
胰腺癌
肿瘤
肿瘤免疫
发表日期：2023
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Combining DNA scaffolds and acoustic force spectroscopy to characterize individual protein bonds

结合DNA支架和声力谱技术来表征单个蛋白质键

期刊:Biophysical Journal
影响因子:3.1
doi:10.1016/j.bpj.2023.05.004
Wang, Yong Jian; Valotteau, Claire; Aimard, Adrien; Villanueva, Lorenzo; Kostrz, Dorota; Follenfant, Maryne; Strick, Terence; Chames, Patrick; Rico, Felix; Gosse, Charlie; Limozin, Laurent
发表日期：2023
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A nanobody activating metabotropic glutamate receptor 4 discriminates between homo- and heterodimers

激活代谢型谷氨酸受体4的纳米抗体能够区分同源二聚体和异源二聚体

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2105848118
Haubrich, Jordi; Font, Joan; Quast, Robert B; Goupil-Lamy, Anne; Scholler, Pauline; Nevoltris, Damien; Acher, Francine; Chames, Patrick; Rondard, Philippe; Prézeau, Laurent; Pin, Jean-Philippe
信号转导
代谢
发表日期：2021
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