日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Human Single-Nucleus RNA Sequencing Identifies CD47 as a Therapeutic Target for Doxorubicin-Induced Cardiomyopathy

人类单核RNA测序鉴定出CD47是阿霉素诱导心肌病的一种治疗靶点

Guo, Zhen; Ataran, Anahita; Ma, Pan; Yu, Wenjing; Hajirezaei, Hamidreza; Valenzuela Ripoll, Carla; Pedersen, Lauren N; Rashidi, Omid; Chan, Mandy M; Shen, Mengcheng; Kelley, Shannon; Sargazi, Alireza; Ozcan, Mualla; Lotfinaghsh, Aynaz; Cho, Yoonje; Diab, Ahmed; Grogan, Felicia; Klaas, Amanda; Pompian, Alexander; Imam, Adnan; Lodhi, Rehman; Zelleke, Amen Bekele; Kovacs, Attila; Margulies, Kenneth B; Szymanski, Jeff; Sardiello, Marco; Razani, Babak; Asnani, Aarti; Kopecky, Benjamin J; Signore, Pierre E; Yi, B Alexander; Basson, Craig T; Ravichandran, Kodi S; Prabhu, Sumanth D; Bergom, Carmen; Schilling, Joel D; Lavine, Kory J; Javaheri, Ali

A Critical Role for the Mitochondrial Pyruvate Carrier in Hepatic Stellate Cell Activation.

线粒体丙酮酸载体在肝星状细胞活化中的关键作用

Habibi Mohammad, Ferguson Daniel, Eichler Sophie J, Chan Mandy M, Fu Christina, Pietka Terri A, Bredemeyer Andrea L, LaPoint Andrew, Shew Trevor M, He Mai, Liss Kim H H, Lutkewitte Andrew J, Cho Kevin, Schilling Joel D, Patti Gary J, Finck Brian N

Induction of TFEB promotes Kupffer cell survival and reduces lipid accumulation in MASLD

TFEB的诱导可促进库普弗细胞存活并减少MASLD中的脂质积累

Chan, Mandy M; Daemen, Sabine; Beatty, Wandy; Byrnes, Kathleen; Cho, Kevin; Ferguson, Daniel; Feldstein, Natalie; Park, Christopher; Guo, Zhen; Park, Arick C; Fu, Christina F; Florczak, Kira L; He, Li; Yang, Bin Q; Javaheri, Ali; Patti, Gary J; Finck, Brian N; Razani, Babak; Schilling, Joel D

Tracing LYVE1(+) peritoneal fluid macrophages unveils two paths to resident macrophage repopulation with differing reliance on monocytes.

追踪 LYVE1(+) 腹腔液巨噬细胞揭示了驻留巨噬细胞重新填充的两条途径,这两条途径对单核细胞的依赖程度不同

Gallerand Alexandre, Han Jichang, Mintz Rachel L, Chen Jing, Lee Daniel D, Chan Mandy M, Harmon Tyler T, Lin Xue, Huckstep Christopher G, Du Siling, Liu Tiantian, Kipnis Jonathan, Lavine Kory J, Schilling Joel D, Morley S Celeste, Zinselmeyer Bernd H, Murphy Kenneth M, Randolph Gwendalyn J

Human serous cavity macrophages and dendritic cells possess counterparts in the mouse with a distinct distribution between species.

人类浆液腔巨噬细胞和树突状细胞在小鼠中也有对应细胞,但不同物种间的分布存在明显差异

Han Jichang, Gallerand Alexandre, Erlich Emma C, Helmink Beth A, Mair Iris, Li Xin, Eckhouse Shaina R, Dimou Francesca M, Shakhsheer Baddr A, Phelps Hannah M, Chan Mandy M, Mintz Rachel L, Lee Daniel D, Schilling Joel D, Finlay Conor M, Allen Judith E, Jakubzick Claudia V, Else Kathryn J, Onufer Emily J, Zhang Nan, Randolph Gwendalyn J

Molecular imaging of macrophage composition and dynamics in MASLD

MASLD中巨噬细胞组成和动态的分子成像

Yang, Bin Q; Chan, Mandy M; Heo, Gyu Seong; Lou, Lanlan; Luehmann, Hannah; Park, Christopher; Li, Alexandria; Lahad, Divangana; Sultan, Deborah; Voller, Peter; Byrnes, Kathleen; Fu, Christina; Liu, Yongjian; Schilling, Joel D

Cutting Edge: Hepatic Stellate Cells Drive the Phenotype of Monocyte-derived Macrophages to Regulate Liver Fibrosis in Metabolic Dysfunction-associated Steatohepatitis.

前沿:肝星状细胞驱动单核细胞衍生巨噬细胞的表型,从而调节代谢功能障碍相关脂肪性肝炎中的肝纤维化

Chan Mandy M, He Li, Finck Brian N, Schilling Joel D, Daemen Sabine

Steatosis drives monocyte-derived macrophage accumulation in human metabolic dysfunction-associated fatty liver disease

脂肪变性驱动单核细胞来源的巨噬细胞在人类代谢功能障碍相关脂肪肝疾病中积聚。

Chan, Mandy M; Daemen, Sabine; Beals, Joseph W; Terekhova, Marina; Yang, Bin Q; Fu, Christina F; He, Li; Park, Arick C; Smith, Gordon I; Razani, Babak; Byrnes, Kathleen; Beatty, Wandy L; Eckhouse, Shaina R; Eagon, J Christopher; Ferguson, Daniel; Finck, Brian N; Klein, Samuel; Artyomov, Maxim N; Schilling, Joel D

Tropism of influenza B viruses in human respiratory tract explants and airway organoids

乙型流感病毒在人类呼吸道外植体和气道类器官中的趋向性

Christine H T Bui, Renee W Y Chan, Mandy M T Ng, M-C Cheung, Ka-Chun Ng, Megan P K Chan, Louisa L Y Chan, Joanne H M Fong, J M Nicholls, J S Malik Peiris, Michael C W Chan