日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Gene delivery of SUMO1-derived peptide rescues neuronal degeneration and motor deficits in a mouse model of Parkinson's disease.

基因递送SUMO1衍生肽可挽救帕金森病小鼠模型中的神经元退化和运动缺陷

Liang Zhaohui, Murugappan Suresh Kanna, Li Yuxuan, Lai Man Nga, Qi Yajing, Wang Yi, Chan Ho Yin Edwin, Lee Marianne M, Chan Michael K

A Simple Strategy for Co-Immobilization of NADH-Dependent Enzymes and NADH for Efficient Biocatalysis in Continuous Flow Reactors

一种用于连续流反应器中高效生物催化的NADH依赖性酶和NADH共固定化的简单策略

Yekta, Reza; Xiong, Xu; Lee, Marianne M; Chan, Michael K

Site-specific in vivo protein SUMOylation via translational incorporation of a proximity-reactive pyrrolysine analogue

通过翻译过程中掺入邻近反应性吡咯赖氨酸类似物,实现位点特异性体内蛋白质SUMO化

Chan, Yuk Hei; Lee, Marianne M; Chan, Michael K

Mechanoresponsive Protein Crystals for NADH Recycling in Multicycle Enzyme Reactions

用于多循环酶反应中NADH回收的机械响应型蛋白质晶体

Yekta, Reza; Xiong, Xu; Li, Jiaxin; Heater, Bradley S; Lee, Marianne M; Chan, Michael K

A Targeted and Protease-Activated Genetically Encoded Melittin-Containing Particle for the Treatment of Cutaneous and Visceral Leishmaniasis

一种靶向蛋白酶激活的基因编码蜂毒肽颗粒,用于治疗皮肤和内脏利什曼病

Habib, Madiha; Zheng, Jiale; Chan, Chin-Fung; Yang, Zaofeng; Wong, Iris L K; Chow, Larry M C; Lee, Marianne M; Chan, Michael K

Pyrrolysine-Inspired in Cellulo Synthesis of an Unnatural Amino Acid for Facile Macrocyclization of Proteins

受吡咯赖氨酸启发,在纤维素中合成一种非天然氨基酸,用于蛋白质的简易大环化

Tai, Jingxuan; Wang, Lin; Chan, Wai Shan; Cheng, Jiahui; Chan, Yuk Hei; Lee, Marianne M; Chan, Michael K

Insights into pyrrolysine function from structures of a trimethylamine methyltransferase and its corrinoid protein complex

从三甲胺甲基转移酶及其咕啉蛋白复合物的结构中揭示吡咯赖氨酸的功能

Li, Jiaxin; Kang, Patrick T; Jiang, Ruisheng; Lee, Jodie Y; Soares, Jitesh A; Krzycki, Joseph A; Chan, Michael K

Insights from the Structure of an Active Form of Bacillus thuringiensis Cry5B

从苏云金芽孢杆菌Cry5B活性形式的结构中获得的启示

Li, Jiaxin; Wang, Lin; Kotaka, Masayo; Lee, Marianne M; Chan, Michael K

Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation

靶向肌红蛋白递送作为提高乏氧癌细胞对辐射敏感性的策略

Yang, Zaofeng; Heater, Bradley S; Cuddington, Clayton T; Palmer, Andre F; Lee, Marianne M M; Chan, Michael K

The pyrrolysine translational machinery as a genetic-code expansion tool

吡咯赖氨酸翻译机制作为一种遗传密码扩展工具

Fekner, Tomasz; Chan, Michael K