日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

TP53 mutations and TET2 deficiency cooperate to drive leukemogenesis and establish an immunosuppressive environment

TP53突变和TET2缺陷协同作用,驱动白血病发生并建立免疫抑制环境。

Zhang, Pu; Whipp, Ethan C; Skuli, Sarah J; Gharghabi, Mehdi; Saygin, Caner; Sher, Steven A; Carroll, Martin; Pan, Xiangyu; Eisenmann, Eric D; Lai, Tzung-Huei; Harrington, Bonnie K; Chan, Wing Keung; Youssef, Youssef; Chen, Bingyi; Penson, Alex; Lewis, Alexander M; Castro, Cynthia R; Fox, Nina; Cihan, Ali; Le Luduec, Jean-Benoit; DeWolf, Susan; Kauffman, Tierney; Mims, Alice S; Canfield, Daniel; Phillips, Hannah; Williams, Katie E; Shaffer, Jami; Lozanski, Arletta; Doong, Tzyy-Jye; Lozanski, Gerard; Mao, Charlene; Walker, Christopher J; Blachly, James S; Daniyan, Anthony F; Alinari, Lapo; Baiocchi, Robert A; Yang, Yiping; Grieselhuber, Nicole R; Campbell, Moray J; Baker, Sharyn D; Blaser, Bradley W; Abdel-Wahab, Omar; Lapalombella, Rosa

Targeting the DNA damage response through TBL1X in mantle cell lymphoma

通过TBL1X靶向套细胞淋巴瘤中的DNA损伤反应

Pray, Betsy; Baiocchi, Ethan; Leon, Sydney; Barta, Brian; Koirala, Shirsha; Tsyba, Liudmyla; Hinterschied, Claire; Carvajal-Moreno, Jessika; Hout, Ian; Nishat, Shamama; Jindal, Udita; Jain, Neeraj; Singh, Satishkumar; Sehgal, Lalit; Chan, Wing Keung; Hanel, Walter; Yalowich, Jack; Baiocchi, Robert A; Alinari, Lapo

Designs of NKG2D-based immunotherapeutics for cancer

基于NKG2D的癌症免疫疗法的设计

Han, Jianfeng; Wang, Youwei; Chan, Godfrey Chi-Fung; Chan, Wing Keung

A sumoylation program is essential for maintaining the mitotic fidelity in proliferating mantle cell lymphoma cells

SUMO化程序对于维持增殖性套细胞淋巴瘤细胞的有丝分裂保真度至关重要。

Hanel, Walter; Lata, Pushpa; Youssef, Youssef; Tran, Ha; Tsyba, Liudmyla; Sehgal, Lalit; Blaser, Bradley W; Huszar, Dennis; Helmig-Mason, JoBeth; Zhang, Liwen; Schrock, Morgan S; Summers, Matthew K; Chan, Wing Keung; Prouty, Alexander; Mundy-Bosse, Bethany L; Chen-Kiang, Selina; Danilov, Alexey V; Maddocks, Kami; Baiocchi, Robert A; Alinari, Lapo

A CS1-NKG2D Bispecific Antibody Collectively Activates Cytolytic Immune Cells against Multiple Myeloma.

CS1-NKG2D双特异性抗体共同激活细胞毒性免疫细胞对抗多发性骨髓瘤

Chan Wing Keung, Kang Siwen, Youssef Youssef, Glankler Erin N, Barrett Emma R, Carter Alex M, Ahmed Elshafa H, Prasad Aman, Chen Luxi, Zhang Jianying, Benson Don M Jr, Caligiuri Michael A, Yu Jianhua

Epigenetic and Posttranscriptional Regulation of CD16 Expression during Human NK Cell Development

人类NK细胞发育过程中CD16表达的表观遗传和转录后调控

Victor, Aaron R; Weigel, Christoph; Scoville, Steven D; Chan, Wing Keung; Chatman, Kelsey; Nemer, Mary M; Mao, Charlene; Young, Karen A; Zhang, Jianying; Yu, Jianhua; Freud, Aharon G; Oakes, Christopher C; Caligiuri, Michael A

IL-18 Drives ILC3 Proliferation and Promotes IL-22 Production via NF-κB

IL-18 通过 NF-κB 途径驱动 ILC3 增殖并促进 IL-22 的产生

Victor, Aaron R; Nalin, Ansel P; Dong, Wenjuan; McClory, Susan; Wei, Min; Mao, Charlene; Kladney, Raleigh D; Youssef, Youssef; Chan, Wing Keung; Briercheck, Edward L; Hughes, Tiffany; Scoville, Steven D; Pitarresi, Jason R; Chen, Charlie; Manz, Sarah; Wu, Lai-Chu; Zhang, Jianying; Ostrowski, Michael C; Freud, Aharon G; Leone, Gustavo W; Caligiuri, Michael A; Yu, Jianhua

Genome-wide single-nucleotide polymorphism analysis revealed SUFU suppression of acute graft-versus-host disease through downregulation of HLA-DR expression in recipient dendritic cells

全基因组单核苷酸多态性分析揭示,SUFU通过下调受体树突状细胞中HLA-DR的表达来抑制急性移植物抗宿主病。

Bari, Rafijul; Hartford, Christine; Chan, Wing Keung; Vong, Queenie; Li, Ying; Gan, Kwan; Zhou, Yinmei; Cheng, Cheng; Kang, Guolian; Shurtleff, Sheila; Turner, Victoria; Pui, Ching-Hon; Downing, James R; Leung, Wing

Multiplex and genome-wide analyses reveal distinctive properties of KIR+ and CD56+ T cells in human blood

多重分析和全基因组分析揭示了人血液中 KIR+ 和 CD56+ T 细胞的独特特性

Chan, Wing Keung; Rujkijyanont, Piya; Neale, Geoffrey; Yang, Jie; Bari, Rafijul; Das Gupta, Neha; Holladay, Martha; Rooney, Barbara; Leung, Wing

The effects of beta-glucan on human immune and cancer cells

β-葡聚糖对人类免疫细胞和癌细胞的影响

Chan, Godfrey Chi-Fung; Chan, Wing Keung; Sze, Daniel Man-Yuen