Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female mice
Nrf2转录因子的缺失会导致雄性和雌性小鼠肝脏中谷胱甘肽S-转移酶Gsta1、Gsta2、Gstm1、Gstm2、Gstm3和Gstm4基因的组成型和诱导型表达显著降低。
期刊:Biochemical Journal
影响因子:4.3
doi:10.1042/BJ20020320
Chanas, Simon A; Jiang, Qing; McMahon, Michael; McWalter, Gail K; McLellan, Lesley I; Elcombe, Clifford R; Henderson, Colin J; Wolf, C Roland; Moffat, Graeme J; Itoh, Ken; Yamamoto, Masayuki; Hayes, John D