日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Enhanced Delivery of Aurora Kinase A Inhibitor Alisertib via Tumor-Targeting Immunoliposome Nanocomplex for Improved Treatment of Cancers Including Atypical Teratoid/Rhabdoid Tumor

利用肿瘤靶向免疫脂质体纳米复合物增强Aurora激酶A抑制剂Alisertib的递送,以改善包括非典型畸胎瘤/横纹肌样瘤在内的癌症的治疗

Kim, Sang-Soo; Moghe, Manish; Rait, Antonina S; Harford, Joe B; Chang, Esther H

scL-2PAM: A Novel Countermeasure That Ameliorates Neuroinflammation and Neuronal Losses in Mice Exposed to an Anticholinesterase Organophosphate

scL-2PAM:一种新型的对抗措施,可减轻暴露于抗胆碱酯酶有机磷酸酯的小鼠的神经炎症和神经元丢失。

Moghe, Manish; Kim, Sang-Soo; Guan, Miaoyin; Rait, Antonina; Pirollo, Kathleen F; Harford, Joe B; Chang, Esther H

TP53 Gene Therapy as a Potential Treatment for Patients with COVID-19

TP53基因疗法作为新冠肺炎患者的潜在治疗方法

Harford, Joe B; Kim, Sang Soo; Pirollo, Kathleen F; Chang, Esther H

Integrated Genomic and Functional microRNA Analysis Identifies miR-30-5p as a Tumor Suppressor and Potential Therapeutic Nanomedicine in Head and Neck Cancer

整合基因组和功能性microRNA分析发现miR-30-5p是头颈癌的肿瘤抑制因子和潜在的治疗性纳米药物。

Saleh, Anthony D; Cheng, Hui; Martin, Scott E; Si, Han; Ormanoglu, Pinar; Carlson, Sophie; Clavijo, Paul E; Yang, Xinping; Das, Rita; Cornelius, Shaleeka; Couper, Jamie; Chepeha, Douglas; Danilova, Ludmila; Harris, Thomas M; Prystowsky, Michael B; Childs, Geoffrey J; Smith, Richard V; Robertson, A Gordon; Jones, Steven J M; Cherniack, Andrew D; Kim, Sang S; Rait, Antonina; Pirollo, Kathleen F; Chang, Esther H; Chen, Zhong; Van Waes, Carter

Activating p53 family member TAp63: A novel therapeutic strategy for targeting p53-altered tumors.

激活 p53 家族成员 TAp63:一种针对 p53 改变肿瘤的新型治疗策略

Gunaratne Preethi H, Pan Yinghong, Rao Abhi K, Lin Chunru, Hernandez-Herrera Anadulce, Liang Ke, Rait Antonina S, Venkatanarayan Avinashnarayan, Benham Ashley L, Rubab Farwah, Kim Sang Soo, Rajapakshe Kimal, Chan Clara K, Mangala Lingegowda S, Lopez-Berestein Gabriel, Sood Anil K, Rowat Amy C, Coarfa Cristian, Pirollo Kathleen F, Flores Elsa R, Chang Esther H

A tumor-targeting nanomedicine carrying the p53 gene crosses the blood-brain barrier and enhances anti-PD-1 immunotherapy in mouse models of glioblastoma

一种携带p53基因的肿瘤靶向纳米药物能够穿过血脑屏障,并在胶质母细胞瘤小鼠模型中增强抗PD-1免疫疗法的疗效。

Kim, Sang-Soo; Harford, Joe B; Moghe, Manish; Slaughter, Tiffani; Doherty, Caroline; Chang, Esther H

Nanocomplex-based TP53 gene therapy promotes anti-tumor immunity through TP53- and STING-dependent mechanisms

基于纳米复合物的TP53基因疗法通过TP53和STING依赖性机制促进抗肿瘤免疫。

Moore, Ellen C; Sun, Lillian; Clavijo, Paul E; Friedman, Jay; Harford, Joe B; Saleh, Anthony D; Van Waes, Carter; Chang, Esther H; Allen, Clint T

Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study

靶向p53基因纳米复合物联合多西他赛治疗晚期实体瘤的安全性和有效性:一项1b期研究

Pirollo, Kathleen F; Nemunaitis, John; Leung, Po Ki; Nunan, Robert; Adams, Jana; Chang, Esther H

Effective treatment of glioblastoma requires crossing the blood-brain barrier and targeting tumors including cancer stem cells: The promise of nanomedicine

有效治疗胶质母细胞瘤需要穿过血脑屏障并靶向肿瘤,包括癌症干细胞:纳米医学的希望

Kim, Sang-Soo; Harford, Joe B; Pirollo, Kathleen F; Chang, Esther H

Isolation and Culturing of Glioma Cancer Stem Cells

胶质瘤癌干细胞的分离与培养

Kim, Sang-Soo; Pirollo, Kathleen F; Chang, Esther H