日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Massive-scale single-nucleus multi-omics identifies novel rare noncoding drivers of Parkinson's disease

大规模单核多组学研究发现帕金森病的新型罕见非编码驱动基因

Menon, Shreya; Turner, Adam W; Chang, Serena H; Johnson, Alia W; Chang, Heather H; Shah, Aayushi J; Zeng, Youjie; Strohlein, Colleen E; Kampman, Lucas; Colston, Courtney; Kozlenkov, Alexey; Dracheva, Stella; Avenali, Micol; Palermo, Giovanni; Ceravolo, Roberto; Valente, Enza Maria; Gabbert, Carolin; Trinh, Joanne; Serrano, Geidy E; Beach, Thomas G; Shulman, Joshua M; Blauwendraat, Cornelis; Montine, Thomas J; Fang, Zih-Hua; Belloy, Michael E; Corces, M Ryan

Conditional neuronal deletion of microRNA-141/200c cluster, but not microRNA-181a/b-1 cluster, is protective against experimental stroke in male mice.

条件性神经元删除 microRNA-141/200c 簇(而非 microRNA-181a/b-1 簇)可保护雄性小鼠免受实验性中风的影响

Xu Lijun, Griffiths Brian, Sun Xiaoyun, Greer Majesty, Chang Heather, McMillin Elijah, Manis Elizabeth, Russo Isabella, Dean Claire Ai Jue, Stary Creed M

Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model

发现对小鼠感染模型有效的 SARS-CoV-2 木瓜蛋白酶样蛋白酶 (PLpro) 抑制剂

Michelle R Garnsey, Matthew C Robinson, Luong T Nguyen, Rhonda Cardin, Joseph Tillotson, Ellene Mashalidis, Aijia Yu, Lisa Aschenbrenner, Amanda Balesano, Amin Behzadi, Britton Boras, Jeanne S Chang, Heather Eng, Andrew Ephron, Tim Foley, Kristen K Ford, James M Frick, Scott Gibson, Li Hao, Brett Hu

Before, during, and after: An Argument for Safety and Improved Outcome of Thrombolysis in Acute Ischemic Stroke with Direct Oral Anticoagulant Treatment

溶栓治疗前、中、后:论证直接口服抗凝剂治疗在急性缺血性卒中溶栓治疗中的安全性和改善疗效

Monjazeb, Sanaz; Chang, Heather V; Lyden, Patrick D

MicroRNA-494 augments fibrotic transformation of human retinal pigment epithelial cells and targets p27 with cell-type specificity

MicroRNA-494 可增强人视网膜色素上皮细胞的纤维化转化,并以细胞类型特异性靶向 p27。

Leng, Theodore; Kamboj, Georgia; Sun, Xiaoyun; Chang, Heather; Davda, Prisha; Greer, Majesty; Stary, Creed M

Cell size sensing in animal cells coordinates anabolic growth rates and cell cycle progression to maintain cell size uniformity

动物细胞中的细胞大小感应协调合成代谢生长率和细胞周期进程,以保持细胞大小的一致性

Miriam Bracha Ginzberg, Nancy Chang, Heather D'Souza, Nish Patel, Ran Kafri, Marc W Kirschner

Rejection of immunogenic tumor clones is limited by clonal fraction

免疫原性肿瘤克隆的排斥受克隆分数限制。

Ron S Gejman # ,Aaron Y Chang # ,Heather F Jones ,Krysta DiKun ,Abraham Ari Hakimi ,Andrea Schietinger ,David A Scheinberg

Apo2L/TRAIL and the death receptor 5 agonist antibody AMG 655 cooperate to promote receptor clustering and antitumor activity

Apo2L/TRAIL 与死亡受体 5 激动剂抗体 AMG 655 协同促进受体聚集和抗肿瘤活性

Jonathan D Graves, Jennifer J Kordich, Tzu-Hsuan Huang, Julia Piasecki, Tammy L Bush, Timothy Sullivan, Ian N Foltz, Wesley Chang, Heather Douangpanya, Thu Dang, Jason W O'Neill, Rommel Mallari, Xiaoning Zhao, Daniel G Branstetter, John M Rossi, Alexander M Long, Xin Huang, Pamela M Holland