日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Mitochondrial bioenergetics and intracellular calcium concentration in primary myotubes from mouse models of malignant hyperthermia

恶性高热小鼠模型原代肌管细胞线粒体生物能量学和细胞内钙浓度

Kaura, Vikas; Chang, Leon; Hopkins, Philip Morgan; Shaw, Marie-Anne

RP9 revisited; RP9 p.(H137L) remains a likely cause of dominant splicing factor-Retinitis Pigmentosa

RP9 再探;RP9 p.(H137L) 突变仍然是显性剪接因子视网膜色素变性的可能病因。

Chang, Leon; Poulter, James A; Webster, Andrew R; Arno, Gavin; Mukherjee, Rajarshi; Lotery, Andrew; Hardcastle, Alison J; Watson, Christopher M; Inglehearn, Chris F

Mapping VEXAS-associated and rare UBA1 variants in the United Kingdom: Insights from patient cohorts and the general population

英国VEXAS相关及罕见UBA1变异的分布图谱:来自患者队列和普通人群的启示

Martinez Rodriguez, Ana; Chang, Leon; Rowczenio, Dorota; Smith, Alexandra; Omoyinmi, Ebun; Poulter, James A; McGregor, Andrew; Francis, Sebastian; Trikha, Roochi; Al-Hakim, Adam; Lok Kong, Kar; Kent, David G; Lachmann, Helen; Kulasekararaj, Austin; Cargo, Catherine; Savic, Sinisa

Characterization of Genetic Landscape and Novel Inflammatory Biomarkers in Patients With Adult-Onset Still's Disease

成人斯蒂尔病患者的遗传图谱和新型炎症生物标志物特征分析

Topping, Joanne; Chang, Leon; Nadat, Fatima; Poulter, James A; Ibbotson, Alice; Lara-Reyna, Samuel; Watson, Christopher M; Carter, Clive; Pournara, Linda P; Zernicke, Jan; Ross, Rebecca L; Cargo, Catherine; Lyons, Paul A; Smith, Kenneth G C; Del Galdo, Francesco; Rech, Jürgen; Fautrel, Bruno; Feist, Eugen; McDermott, Michael F; Savic, Sinisa

FACS-based detection of extracellular ASC specks from NLRP3 inflammasomes in inflammatory diseases.

基于 FACS 检测炎症性疾病中 NLRP3 炎症小体的细胞外 ASC 斑点

Topping Joanne, Lara-Reyna Samuel, Ibbotson Alice, Jarosz-Griffiths Heledd, Chang Leon, Poulter James, Peckham Daniel, McDermott Michael F, Savic Sinisa

Identification of highly selective SIK1/2 inhibitors that modulate innate immune activation and suppress intestinal inflammation

鉴定能够调节先天免疫激活并抑制肠道炎症的高选择性SIK1/2抑制剂

Babbe, Holger; Sundberg, Thomas B; Tichenor, Mark; Seierstad, Mark; Bacani, Genesis; Berstler, James; Chai, Wenying; Chang, Leon; Chung, De Michael; Coe, Kevin; Collins, Bernard; Finley, Michael; Guletsky, Alexander; Lemke, Christopher T; Mak, Puiying A; Mathur, Ashok; Mercado-Marin, Eduardo V; Metkar, Shailesh; Raymond, Donald D; Rives, Marie-Laure; Rizzolio, Michele; Shaffer, Paul L; Smith, Russell; Smith, Jacqueline; Steele, Ruth; Steffens, Helena; Suarez, Javier; Tian, Gaochao; Majewski, Nathan; Volak, Laurie P; Wei, Jianmei; Desai, Prerak T; Ong, Luvena L; Koudriakova, Tatiana; Goldberg, Steven D; Hirst, Gavin; Kaushik, Virendar K; Ort, Tatiana; Seth, Nilufer; Graham, Daniel B; Plevy, Scott; Venable, Jennifer D; Xavier, Ramnik J; Towne, Jennifer E

An Association between OXPHOS-Related Gene Expression and Malignant Hyperthermia Susceptibility in Human Skeletal Muscle Biopsies

人类骨骼肌活检中氧化磷酸化相关基因表达与恶性高热易感性之间的关联

Chang, Leon; Motley, Rebecca; Daly, Catherine L; Diggle, Christine P; Hopkins, Philip M; Shaw, Marie-Anne

The mode of action of IL-23 in experimental inflammatory arthritic pain and disease

IL-23在实验性炎症性关节炎疼痛和疾病中的作用机制

Lee, Kevin M-C; Lupancu, Tanya; Chang, Leon; Manthey, Carl L; Zeeman, Martha; Fourie, Anne M; Hamilton, John A

Comparison of Transcriptomic Changes in Survivors of Exertional Heat Illness with Malignant Hyperthermia Susceptible Patients

比较运动性热病幸存者与恶性高热易感患者的转录组变化

Chang, Leon; Gardner, Lois; House, Carol; Daly, Catherine; Allsopp, Adrian; Roiz de Sa, Daniel; Shaw, Marie-Anne; Hopkins, Philip M

Treatment of resistant metastatic melanoma using sequential epigenetic therapy (decitabine and panobinostat) combined with chemotherapy (temozolomide)

采用序贯表观遗传疗法(地西他滨和帕比司他)联合化疗(替莫唑胺)治疗耐药性转移性黑色素瘤

Xia, Chang; Leon-Ferre, Roberto; Laux, Douglas; Deutsch, Jeremy; Smith, Brian J; Frees, Melanie; Milhem, Mohammed