Chang Long-Sheng相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

NKG2D upregulation sensitizes tumors to combined anti-PD1 and anti-VEGF therapy and prevents hearing loss

NKG2D 上调可增强肿瘤对联合抗 PD-1 和抗 VEGF 疗法的敏感性，并预防听力损失。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-026-68865-8

Lu, Simeng; Yin, Zhenzhen; Wu, Limeng; Sun, Yao; Chen, Jie; Wu, Lai Man Natalie; Oblinger, Janet L; Blake, Day C; Xiu, Bingyu; Landegger, Lukas D; Seist, Richard; Ho, William; Jones, Adam P; Muzikansky, Alona; Stankovic, Konstantina M; Plotkin, Scott R; Chang, Long-Sheng; Xu, Lei

发表日期：2026

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Combining Brigatinib with mTOR Inhibition to Effectively Treat NF2-SWN-Associated and Sporadic NF2-Deficient Meningiomas

布加替尼联合 mTOR 抑制剂可有效治疗 NF2-SWN 相关和散发性 NF2 缺陷型脑膜瘤

期刊:Cancer Research Communications

影响因子:3.3

doi:10.1158/2767-9764.CRC-25-0563

Chang, Long-Sheng; Oblinger, Janet L; Wu, Lai Man Natalie; Miller, Cecelia; Burns, Sarah S

发表日期：2026

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Single-cell and Spatial Omics Reveals Region-Specific Plasticity and Therapeutic Vulnerabilities in Metastatic High-Risk Neuroblastoma

单细胞和空间组学揭示转移性高危神经母细胞瘤的区域特异性可塑性和治疗脆弱性

doi:10.1101/2025.10.19.681936

Wu, Lai Man Natalie; Oblinger, Janet L; Xin, Dazhuan; Rao, Rohit; Zhang, Feng; Adam, Mike; Lopez-Nunez, Oscar; Szabo, Sara; von Allmen, Daniel; Chang, Long-Sheng; Weiss, Brian D; Lu, Q Richard

细胞生物学

发表日期：2025

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Enhanced Tumor Control and Hearing Loss Prevention Achieved with Combined Immune Checkpoint Inhibitor and Anti-VEGF Therapy in Vestibular Schwannoma Model

在脑前庭神经鞘瘤模型中，联合使用免疫检查点抑制剂和抗VEGF疗法可增强肿瘤控制并预防听力损失。

doi:10.1101/2024.12.29.630658

Lu, Simeng; Yin, Zhenzhen; Wu, Limeng; Sun, Yao; Chen, Jie; Wu, Lai Man Natalie; Oblinger, Janet L; Blake, Day Caven; Landegger, Lukas D; Seist, Richard; Ho, William; Xiu, Bingyu; Jones, Adam P; Muzikansky, Alona; Stankovic, Konstantina M; Plotkin, Scott R; Chang, Long-Sheng; Xu, Lei

免疫/内分泌

前庭神经鞘瘤

发表日期：2024

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Proteasomal pathway inhibition as a potential therapy for NF2-associated meningioma and schwannoma

蛋白酶体通路抑制作为NF2相关脑膜瘤和神经鞘瘤的潜在治疗方法

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noad037

Bhattacharyya, Srirupa; Oblinger, Janet L; Beauchamp, Roberta L; Yin, Zhenzhen; Erdin, Serkan; Koundinya, Priya; Ware, Anna D; Ferrer, Marc; Jordan, Justin T; Plotkin, Scott R; Xu, Lei; Chang, Long-Sheng; Ramesh, Vijaya

发表日期：2023

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Neurofibromatosis: Molecular Pathogenesis and Natural Compounds as Potential Treatments

神经纤维瘤病：分子发病机制及天然化合物作为潜在治疗方法

期刊:Frontiers in Oncology

影响因子:3.3

doi:10.3389/fonc.2021.698192

Amaravathi, Anusha; Oblinger, Janet L; Welling, D Bradley; Kinghorn, A Douglas; Chang, Long-Sheng

发表日期：2021

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Update on Phytochemical and Biological Studies on Rocaglate Derivatives from Aglaia Species

关于阿格莱亚属植物中罗卡格酯衍生物的植物化学和生物学研究的最新进展

期刊:Planta Medica

doi:10.1055/a-1401-9562

Agarwal, Garima; Chang, Long-Sheng; Soejarto, Djaja Doel; Kinghorn, A Douglas

发表日期：2021

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Early phase clinical studies of AR-42, a histone deacetylase inhibitor, for neurofibromatosis type 2-associated vestibular schwannomas and meningiomas

针对2型神经纤维瘤病相关前庭神经鞘瘤和脑膜瘤，组蛋白去乙酰化酶抑制剂AR-42的早期临床研究

期刊:Laryngoscope Investigative Otolaryngology

影响因子:1.7

doi:10.1002/lio2.643

Welling, D Bradley; Collier, Katharine A; Burns, Sarah S; Oblinger, Janet L; Shu, Edina; Miles-Markley, Beth A; Hofmeister, Craig C; Makary, Mina S; Slone, H Wayne; Blakeley, Jaishri O; Mansouri, S Alireza; Neff, Brian A; Jackler, Robert K; Mortazavi, Amir; Chang, Long-Sheng

前庭神经鞘瘤

发表日期：2021

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EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma

EPH受体信号通路作为NF2缺陷型脑膜瘤的新型治疗靶点

期刊:Neuro-Oncology

影响因子:13.4

doi:10.1093/neuonc/noy046

Angus, Steven P; Oblinger, Janet L; Stuhlmiller, Timothy J; DeSouza, Patrick A; Beauchamp, Roberta L; Witt, Luke; Chen, Xin; Jordan, Justin T; Gilbert, Thomas S K; Stemmer-Rachamimov, Anat; Gusella, James F; Plotkin, Scott R; Haggarty, Stephen J; Chang, Long-Sheng; Johnson, Gary L; Ramesh, Vijaya

发表日期：2018

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Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

针对罕见肿瘤综合征2型神经纤维瘤病，采用传统方法和系统生物学方法进行药物研发。

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0197350

Allaway, Robert; Angus, Steve P; Beauchamp, Roberta L; Blakeley, Jaishri O; Bott, Marga; Burns, Sarah S; Carlstedt, Annemarie; Chang, Long-Sheng; Chen, Xin; Clapp, D Wade; Desouza, Patrick A; Erdin, Serkan; Fernandez-Valle, Cristina; Guinney, Justin; Gusella, James F; Haggarty, Stephen J; Johnson, Gary L; La Rosa, Salvatore; Morrison, Helen; Petrilli, Alejandra M; Plotkin, Scott R; Pratap, Abhishek; Ramesh, Vijaya; Sciaky, Noah; Stemmer-Rachamimov, Anat; Stuhlmiller, Tim J; Talkowski, Michael E; Welling, D Bradley; Yates, Charles W; Zawistowski, Jon S; Zhao, Wen-Ning

发表日期：2018

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