Chang Yu-Chan相关文献与解析，生知库 | 链接生命科学的每一步

Lin, Yu-Lung; Liu, Pei-Yao; Tsai, Yu-Ling; Lin, Chien-Ming; Chen, Yu-Guang; Sun, Jun-Ren; Chang, Yu-Chan; Tsai, Wen-Chiuan; Ding, Yi-Xuan; Liu, Chi-Wei; Wang, Shih-Yun; Chen, Ying-Chuan

信号转导

NF1

代谢

发表日期：2026

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SLC25A11-mediated reprogramming of mitochondrial redox state and lipid peroxidation confers NRF2-dependent ferroptosis resistance in biliary tract cancer.

SLC25A11介导的线粒体氧化还原状态和脂质过氧化的重编程赋予胆道癌NRF2依赖性铁死亡抵抗力。

期刊:Cellular & Molecular Biology Letters

影响因子:10.2

doi:10.1186/s11658-025-00843-2

Lin Yu-Yu, Kuo Han-Hsi, He Zhao-Jing, Chung Hsin-Yi, Kim Cheorl-Ho, Pan Yi-Ru, Wu Meng-Ju, Chan Ming-Hsien, Yeh Chun-Nan, Chiang Nai-Jung, Chen Ming-Huang, Chang Yu-Chan

High-dose irradiation promotes macrophage-mediated engulfment of triple-negative breast cancer through M1 polarization via the IKZF1-CCL5 axis.

高剂量辐射通过 IKZF1-CCL5 轴促进巨噬细胞介导的 M1 极化，从而吞噬三阴性乳腺癌。

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-026-02713-6

Kuo Han-Hsi, Chan Hui-Wen, Liu Chun-Yu, Chen Ming-Huang, Lee Yi-Jang, Chuang Hui-Yen, Chang Yu-Chan

Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells

角鲨烯合酶通过补充胆固醇诱导ERα表达，从而赋予肺癌细胞他汀类药物耐药性。

期刊:Cancer Cell International

影响因子:6

doi:10.1186/s12935-026-04220-7

Yang, Yi-Fang; Chang, Yu-Chan; Chan, Ming-Hsien; Lin, Min-Hsi; Yang, Chih-Jen; Huang, Ming-Shyan; Jan, Yi-Hua; Hsiao, Michael

Editorial: Deciphering macrophage polarization/transition in human inflammatory disease and cancer

社论：解读人类炎症性疾病和癌症中巨噬细胞的极化/转变

期刊:Frontiers in Immunology

影响因子:5.9

doi:10.3389/fimmu.2026.1804398

Chang, Peter Mu-Hsin; Chiang, Nai-Jung; Fiorcari, Stefania; Chang, Yu-Chan

Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma

三级淋巴结构和肿瘤浸润淋巴细胞在胆管癌中的比较影响

期刊:Journal for ImmunoTherapy of Cancer

影响因子:10.6

doi:10.1136/jitc-2024-010173

Chung, Shin-Yi; Yeh, Yi-Chen; Huang, Chien-Jung; Chiang, Nai-Jung; Hsu, Dennis Shin-Shian; Chan, Ming-Hsien; Lu, Meng-Lun; Hsu, Tzu-Sheng; Hung, Yi-Ping; Yeh, Chun-Nan; Hsiao, Michael; Chang, Yu-Chan; Wang, Yu-Chao; Chen, Ming-Huang

Construction of hot tumor classification models in gastrointestinal cancers

构建胃肠道肿瘤热点肿瘤分类模型

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/s12967-025-06230-x

Huang, Chien-Jung; Liu, Guan-Ting; Yeh, Yi-Chen; Chung, Shin-Yi; Chang, Yu-Chan; Chiang, Nai-Jung; Lu, Meng-Lun; Huang, Wei-Ning; Chen, Ming-Huang; Wang, Yu-Chao

Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress.

靶向 ESR1 可恢复 SQSTM1 依赖性自噬，并使 ER 阳性乳腺癌对氧化应激和辐射应激更加敏感。

期刊:Cell Death Discovery

影响因子:7

doi:10.1038/s41420-025-02755-8

Yang Yi-Fang, He Zhao-Jing, Kuo Han-Hsi, Lin Yu-Yu, Kim Cheorl-Ho, Cai Huei-Yu, Chen Chi-Long, Hsiao Michael, Chen Ying-Chung, Chang Peter Mu-Hsin, Chang Yu-Chan

The correlation between LAG-3 expression and the efficacy of chemoimmunotherapy in advanced biliary tract cancer

LAG-3表达与晚期胆道癌化疗免疫疗法疗效的相关性

期刊:Cancer Immunology Immunotherapy

影响因子:5.1

doi:10.1007/s00262-024-03878-0

Tang, Cheng-Yu; Lin, Yi-Ting; Yeh, Yi-Chen; Chung, Shin-Yi; Chang, Yu-Chan; Hung, Yi-Ping; Chen, San-Chi; Chen, Ming-Huang; Chiang, Nai-Jung

Matrix Metalloproteinases and Their Inhibitors in the Pathogenesis of Epithelial Differentiation, Vascular Disease, Endometriosis, and Ocular Fibrotic Pterygium

基质金属蛋白酶及其抑制剂在表皮分化、血管疾病、子宫内膜异位症和眼纤维性翼状胬肉发病机制中的作用

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms26125553

Park, Jun-Young; Choi, Yeonwoo; Kim, Hee-Do; Kuo, Han-Hsi; Chang, Yu-Chan; Kim, Cheorl-Ho

发表日期：2025

文献求助收藏

RNF128 regulates the adaptive metabolic response to fasting by modulating PPARα function

RNF128通过调节PPARα功能来调控对禁食的适应性代谢反应。

SLC25A11-mediated reprogramming of mitochondrial redox state and lipid peroxidation confers NRF2-dependent ferroptosis resistance in biliary tract cancer.

SLC25A11介导的线粒体氧化还原状态和脂质过氧化的重编程赋予胆道癌NRF2依赖性铁死亡抵抗力。

High-dose irradiation promotes macrophage-mediated engulfment of triple-negative breast cancer through M1 polarization via the IKZF1-CCL5 axis.

高剂量辐射通过 IKZF1-CCL5 轴促进巨噬细胞介导的 M1 极化，从而吞噬三阴性乳腺癌。

Squalene synthase induces ERα expression via cholesterol supplementation to confer statin resistance in lung cancer cells

角鲨烯合酶通过补充胆固醇诱导ERα表达，从而赋予肺癌细胞他汀类药物耐药性。

Editorial: Deciphering macrophage polarization/transition in human inflammatory disease and cancer

社论：解读人类炎症性疾病和癌症中巨噬细胞的极化/转变

Comparative impact of tertiary lymphoid structures and tumor-infiltrating lymphocytes in cholangiocarcinoma

三级淋巴结构和肿瘤浸润淋巴细胞在胆管癌中的比较影响

Construction of hot tumor classification models in gastrointestinal cancers

构建胃肠道肿瘤热点肿瘤分类模型

Targeting ESR1 restores SQSTM1-dependent autophagy and sensitizes ER-positive breast cancer to oxidative and radiation stress.

靶向 ESR1 可恢复 SQSTM1 依赖性自噬，并使 ER 阳性乳腺癌对氧化应激和辐射应激更加敏感。

The correlation between LAG-3 expression and the efficacy of chemoimmunotherapy in advanced biliary tract cancer

LAG-3表达与晚期胆道癌化疗免疫疗法疗效的相关性

Matrix Metalloproteinases and Their Inhibitors in the Pathogenesis of Epithelial Differentiation, Vascular Disease, Endometriosis, and Ocular Fibrotic Pterygium

基质金属蛋白酶及其抑制剂在表皮分化、血管疾病、子宫内膜异位症和眼纤维性翼状胬肉发病机制中的作用