Discovery of YJZ5118: A Potent and Highly Selective Irreversible CDK12/13 Inhibitor with Synergistic Effects in Combination with Akt Inhibition.
YJZ5118 的发现：一种强效且高选择性的不可逆 CDK12/13 抑制剂，与 Akt 抑制剂联合使用具有协同效应
期刊:Journal of Medicinal Chemistry
影响因子:6.8
doi:10.1021/acs.jmedchem.5c00127
Yang Jianzhang, Chang Yu, Zhou Kaijie, Huang Weixue, Tien Jean Ching-Yi, Zhang Pujuan, Liu Wenyan, Zhou Licheng, Zhou Yang, Ren Xiaomei, Mannan Rahul, Mahapatra Somnath, Zhang Yuping, Hamadeh Rudana, Ervine Grafton, Wang Zhen, Wang George Xiaoju, Chinnaiyan Arul M, Ding Ke
