日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Decreased dopaminergic inhibition of pyramidal neurons in anterior cingulate cortex maintains chronic neuropathic pain

前扣带皮层锥体神经元多巴胺能抑制减少维持慢性神经性疼痛

Kevin Lançon, Chaoling Qu, Edita Navratilova, Frank Porreca, Philippe Séguéla

Antihyperalgesic effects of Meteorin in the rat chronic constriction injury model: a replication study

镍纹蛋白在慢性压迫性损伤大鼠模型中的抗痛觉过敏作用:一项复制研究

Jennifer Y Xie, Chaoling Qu, Gordon Munro, Kenneth A Petersen, Frank Porreca

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

CRISPR/Cas9 编辑 Nf1 基因,确定 CRMP2 是 1 型神经纤维瘤病相关疼痛的治疗靶点,该疼痛可通过 (S)-拉科酰胺逆转

Aubin Moutal, Xiaofang Yang, Wennan Li, Kerry B Gilbraith, Shizhen Luo, Song Cai, Liberty François-Moutal, Lindsey A Chew, Seul Ki Yeon, Shreya S Bellampalli, Chaoling Qu, Jennifer Y Xie, Mohab M Ibrahim, May Khanna, Ki Duk Park, Frank Porreca, Rajesh Khanna

Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential

低滥用潜力的 CRMP2 肽适体可持续缓解持续的实验性神经性疼痛

Jennifer Y Xie, Lindsey A Chew, Xiaofang Yang, Yuying Wang, Chaoling Qu, Yue Wang, Lauren M Federici, Stephanie D Fitz, Matthew S Ripsch, Michael R Due, Aubin Moutal, May Khanna, Fletcher A White, Todd W Vanderah, Philip L Johnson, Frank Porreca, Rajesh Khanna

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology

(S)-拉科酰胺抑制 CRMP2 磷酸化可通过星座药理学确定的不同类别的感觉神经元减少术后和神经性疼痛行为

Aubin Moutal, Lindsey A Chew, Xiaofang Yang, Yue Wang, Seul Ki Yeon, Edwin Telemi, Seeneen Meroueh, Ki Duk Park, Raghuraman Shrinivasan, Kerry B Gilbraith, Chaoling Qu, Jennifer Y Xie, Amol Patwardhan, Todd W Vanderah, May Khanna, Frank Porreca, Rajesh Khanna

Endogenous opioid activity in the anterior cingulate cortex is required for relief of pain

前扣带皮层中的内源性阿片类物质活性是缓解疼痛的必要条件

Edita Navratilova, Jennifer Yanhua Xie, Diana Meske, Chaoling Qu, Kozo Morimura, Alec Okun, Naohisa Arakawa, Michael Ossipov, Howard L Fields, Frank Porreca

Pain relief produces negative reinforcement through activation of mesolimbic reward-valuation circuitry

疼痛缓解通过激活中脑边缘奖励评价回路产生负强化

Edita Navratilova, Jennifer Y Xie, Alec Okun, Chaoling Qu, Nathan Eyde, Shuang Ci, Michael H Ossipov, Tamara King, Howard L Fields, Frank Porreca