日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Intellectual disability risk gene RFX4 regulates cortical neurogenesis by restraining neuronal differentiation

智力障碍风险基因RFX4通过抑制神经元分化来调控皮层神经发生。

Determan, Julianna J; Chapman, Gareth; Crump, Sydney R; Batool, Faiza; Malik, Sofia; Gujral, Taran; Buchser, William; Valentine, Caleb; Elia, Serena; Sentmanat, Monica; Cui, Xiaoxia; Jetter, Haley; Kroll, Kristen L

Autism- and intellectual disability-associated MYT1L mutation alters human cortical interneuron differentiation, maturation, and physiology.

与自闭症和智力障碍相关的 MYT1L 突变会改变人类皮层中间神经元的分化、成熟和生理功能

Prakasam Ramachandran, Determan Julianna, Chapman Gareth, Narasimhan Mishka, Shen Renata, Saleh Maamoon, Kaushik Komal, Gontarz Paul, Meganathan Kesavan, Hakim Bilal, Zhang Bo, Huettner James E, Kroll Kristen L

Tatton-Brown-Rahman-Syndrome-associated DNMT3A mutations de-repress cortical interneuron differentiation to disrupt neuronal network function

Tatton-Brown-Rahman综合征相关的DNMT3A突变会解除对皮质中间神经元分化的抑制,从而破坏神经元网络功能。

Chapman, Gareth; Determan, Julianna; Edwards, John R; Batool, Faiza; Huettner, James E; Prakasam, Ramachandran; Crump, Sydney R; Jetter, Haley; Gabel, Harrison W; Kroll, Kristen L

Duplication Versus Deletion Through the Lens of 15q13.3: Clinical and Research Implications of Studying Copy Number Variants Associated with Neuropsychiatric Disorders in Induced Pluripotent Stem Cell-Derived Neurons

从15q13.3的角度探讨重复与缺失:研究诱导多能干细胞衍生神经元中与神经精神疾病相关的拷贝数变异的临床和研究意义

Antony, Irene; Narasimhan, Mishka; Shen, Renata; Prakasam, Ramachandran; Kaushik, Komal; Chapman, Gareth; Kroll, Kristen L

Using induced pluripotent stem cells to investigate human neuronal phenotypes in 1q21.1 deletion and duplication syndrome

利用诱导多能干细胞研究1q21.1缺失和重复综合征的人类神经元表型

Chapman, Gareth; Alsaqati, Mouhamed; Lunn, Sharna; Singh, Tanya; Linden, Stefanie C; Linden, David E J; van den Bree, Marianne B M; Ziller, Mike; Owen, Michael J; Hall, Jeremy; Harwood, Adrian J; Syed, Yasir Ahmed

Deducing the cellular mechanisms associated with the potential genotoxic impact of gold and silver engineered nanoparticles upon different lung epithelial cell lines in vitro

推断金和银工程纳米粒子对不同肺上皮细胞系的潜在遗传毒性影响相关的细胞机制

Samantha V Llewellyn, Wolfgang J Parak, Jonas Hühn, Michael J Burgum, Stephen J Evans, Katherine E Chapman, Gareth J S Jenkins, Shareen H Doak, Martin J D Clift

The ratio of ursodeoxycholyltaurine to 7-oxolithocholyltaurine serves as a biomarker of decreased 11β-hydroxysteroid dehydrogenase 1 activity in mouse

熊去氧胆酸牛磺酸与 7-氧代石胆酸牛磺酸的比率可作为小鼠 11β-羟基类固醇脱氢酶 1 活性降低的生物标志物

Michael Weingartner, Simon Stücheli, Denise V Kratschmar, Julia Birk, Petra Klusonova, Karen E Chapman, Gareth G Lavery, Alex Odermatt

Neonatal complete Freund's adjuvant-induced inflammation does not induce or alter hyperalgesic priming or alter adult distributions of C-fibre dorsal horn innervation

新生儿完全弗氏佐剂诱发的炎症不会诱发或改变痛觉过敏启动,也不会改变成人 C 纤维背角神经支配的分布

Andrew H Cooper, Jenna M Hanmer, Victoria Chapman, Gareth J Hathway

Lamina-specific population encoding of cutaneous signals in the spinal dorsal horn using multi-electrode arrays

使用多电极阵列对脊髓背角皮肤信号进行层板特异性群体编码

Charles M Greenspon, Emma E Battell, Ian M Devonshire, Lucy F Donaldson, Victoria Chapman, Gareth J Hathway

PM478. Imaging the effects of d-amphetamine in the human brain for modelling dopaminergic alterations in schizophrenia

PM478. 利用成像技术研究右旋安非他明对人脑的影响,以模拟精神分裂症中的多巴胺能改变

Radtke, Franziska A; Chapman, Gareth; Hall, Jeremy; Syed, Yasir A; Katsumasa, Sogo; Friedrich, M-E; Cambioli, L; Dold, M; Lanzenberger, R; Kasper, S; Winkler, D; Koseki, Maiko; Hashimoto, Tasuku; Tsukiji, Mariko; Sakurai, Daichi; Kanahra, Nobuhisa; Hasegawa, Tadashi; Iyo, Masaomi; Kim, Tak Wan; Lim, Kyung-Ok; Lee, Tae Young; Sohn, William; Kwak, Seo Yeon; Kwon, Jun Soo; Willeit, Matthäus; Popovic, Ana; Bauer, Martin; Bartova, Lucie; Sauerzopf, Ulrich; Nics, Lukas; Mitterhauser, Markus; Wadsak, Wolfgang; Praschak-Rieder, Nicole; Kasper, Siegfried