日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Enabling novel paradigms: a biological questions-based approach to human chemical hazard and drug safety assessment

构建全新范式：基于生物学问题的人类化学危害和药物安全评估方法

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfad124
Berridge, Brian R; Bucher, John R; Sistare, Frank; Stevens, James L; Chappell, Grace A; Clemons, Meredith; Snow, Samantha; Wignall, Jessica; Shipkowski, Kelly A
发表日期：2024
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Evaluation of Transcriptomic Responses in Livers of Mice Exposed to the Short-Chain PFAS Compound HFPO-DA

评估暴露于短链 PFAS 化合物 HFPO-DA 的小鼠肝脏转录组反应

期刊:Frontiers in Toxicology
影响因子:4.6
doi:10.3389/ftox.2022.937168
Heintz, Melissa M; Chappell, Grace A; Thompson, Chad M; Haws, Laurie C
FAS
发表日期：2022
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Crypt and Villus Transcriptomic Responses in Mouse Small Intestine Following Oral Exposure to Hexavalent Chromium

小鼠小肠隐窝和绒毛转录组对口服六价铬的反应

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfab152
Chappell, Grace A; Wolf, Jeffrey C; Thompson, Chad M
Mouse
发表日期：2022
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Assessment of Mechanistic Data for Hexavalent Chromium-Induced Rodent Intestinal Cancer Using the Key Characteristics of Carcinogens

利用致癌物的关键特征评估六价铬诱导啮齿动物肠癌的机制数据

期刊:Toxicological Sciences
影响因子:4.1
doi:10.1093/toxsci/kfaa187
Chappell, Grace A; Wikoff, Daniele S; Thompson, Chad M
肿瘤
肠癌
肿瘤免疫
发表日期：2021
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Assessment of the Mode of Action Underlying the Effects of GenX in Mouse Liver and Implications for Assessing Human Health Risks

评估GenX在小鼠肝脏中的作用机制及其对评估人类健康风险的意义

期刊:Toxicologic Pathology
影响因子:1.8
doi:10.1177/0192623320905803
Chappell, Grace A; Thompson, Chad M; Wolf, Jeffrey C; Cullen, John M; Klaunig, James E; Haws, Laurie C
Human
Mouse
发表日期：2020
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Sex-specific differences in genotoxic and epigenetic effects of 1,3-butadiene among mouse tissues

1,3-丁二烯对小鼠组织基因毒性和表观遗传效应的性别差异

期刊:Archives of Toxicology
影响因子:6.9
doi:10.1007/s00204-018-2374-x
Lewis, Lauren; Chappell, Grace A; Kobets, Tetyana; O'Brian, Bridget E; Sangaraju, Dewakar; Kosyk, Oksana; Bodnar, Wanda; Tretyakova, Natalia Y; Pogribny, Igor P; Rusyn, Ivan
毒理研究
表观遗传
发表日期：2019
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Comparison of Gene Expression Responses in the Small Intestine of Mice Following Exposure to 3 Carcinogens Using the S1500+ Gene Set Informs a Potential Common Adverse Outcome Pathway

利用S1500+基因集比较小鼠暴露于3种致癌物后小肠的基因表达反应，揭示潜在的共同不良结局通路

期刊:Toxicologic Pathology
影响因子:1.8
doi:10.1177/0192623319873882
Chappell, Grace A; Rager, Julia E; Wolf, Jeffrey; Babic, Milos; LeBlanc, Kyle J; Ring, Caroline L; Harris, Mark A; Thompson, Chad M
信号转导
肿瘤
肿瘤免疫
发表日期：2019
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Variation in DNA-Damage Responses to an Inhalational Carcinogen (1,3-Butadiene) in Relation to Strain-Specific Differences in Chromatin Accessibility and Gene Transcription Profiles in C57BL/6J and CAST/EiJ Mice

C57BL/6J 和 CAST/EiJ 小鼠吸入致癌物（1,3-丁二烯）后 DNA 损伤反应的差异与染色质可及性和基因转录谱的品系特异性差异有关

期刊:Environmental Health Perspectives
影响因子:9.8
doi:10.1289/EHP1937
Chappell, Grace A; Israel, Jennifer W; Simon, Jeremy M; Pott, Sebastian; Safi, Alexias; Eklund, Karl; Sexton, Kenneth G; Bodnar, Wanda; Lieb, Jason D; Crawford, Gregory E; Rusyn, Ivan; Furey, Terrence S
肿瘤
肿瘤免疫
发表日期：2017
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Benchmark Dose Modeling Estimates of the Concentrations of Inorganic Arsenic That Induce Changes to the Neonatal Transcriptome, Proteome, and Epigenome in a Pregnancy Cohort

妊娠队列中诱导新生儿转录组、蛋白质组和表观基因组改变的无机砷浓度基准剂量模型估计

期刊:Chemical Research in Toxicology
影响因子:3.8
doi:10.1021/acs.chemrestox.7b00221
Rager, Julia E; Auerbach, Scott S; Chappell, Grace A; Martin, Elizabeth; Thompson, Chad M; Fry, Rebecca C
表观遗传
发表日期：2017
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A mouse model of alcoholic liver fibrosis-associated acute kidney injury identifies key molecular pathways.

利用酒精性肝纤维化相关急性肾损伤的小鼠模型，确定了关键的分子通路

期刊:Toxicology and Applied Pharmacology
影响因子:3.4
doi:10.1016/j.taap.2016.09.011
Furuya Shinji, Chappell Grace A, Iwata Yasuhiro, Uehara Takeki, Kato Yuki, Kono Hiroshi, Bataller Ramon, Rusyn Ivan
毒理研究
肾损伤
Mouse
发表日期：2016
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