日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Incorporating Uremic Solute-mediated Inhibition of OAT1/3 Improves PBPK Prediction of Tenofovir Renal and Systemic Disposition in Patients with Severe Kidney Disease.

将尿毒症溶质介导的 OAT1/3 抑制纳入 PBPK 预测,可改善重度肾病患者替诺福韦肾脏和全身分布情况

Chang Shih-Yu, Huang Weize, Chapron Alenka, Quiñones Antonio J López, Wang Joanne, Isoherranen Nina, Shen Danny D, Kelly Edward J, Himmelfarb Jonathan, Yeung Catherine K

Recent advances in the ontogeny of drug disposition

药物处置个体发育的最新进展

Chapron, Brian D; Chapron, Alenka; Leeder, J Steven

An Improved Vascularized, Dual-Channel Microphysiological System Facilitates Modeling of Proximal Tubular Solute Secretion

改进的血管化双通道微生理系统有助于模拟近端肾小管溶质分泌

Chapron, Alenka; Chapron, Brian D; Hailey, Dale W; Chang, Shih-Yu; Imaoka, Tomoki; Thummel, Kenneth E; Kelly, Edward; Himmelfarb, Jonathan; Shen, Danny; Yeung, Catherine K

Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system

利用人细胞衍生的微生理系统重新评估巨蛋白在肾脏维生素D稳态中的作用

Chapron, Brian D; Chapron, Alenka; Phillips, Brian; Okoli, Miracle C; Shen, Danny D; Kelly, Edward J; Himmelfarb, Jonathan; Thummel, Kenneth E

Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D(3)-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans.

多态性人类磺基转移酶 2A1 介导 25-羟基维生素 D(3)-3-O-硫酸盐的形成,这是人体内主要的循环维生素 D 代谢物

Wong Timothy, Wang Zhican, Chapron Brian D, Suzuki Mizuki, Claw Katrina G, Gao Chunying, Foti Robert S, Prasad Bhagwat, Chapron Alenka, Calamia Justina, Chaudhry Amarjit, Schuetz Erin G, Horst Ronald L, Mao Qingcheng, de Boer Ian H, Thornton Timothy A, Thummel Kenneth E

Development of a microphysiological model of human kidney proximal tubule function

建立人类肾近端小管功能的微生理模型

Weber, Elijah J; Chapron, Alenka; Chapron, Brian D; Voellinger, Jenna L; Lidberg, Kevin A; Yeung, Catherine K; Wang, Zhican; Yamaura, Yoshiyuki; Hailey, Dale W; Neumann, Thomas; Shen, Danny D; Thummel, Kenneth E; Muczynski, Kimberly A; Himmelfarb, Jonathan; Kelly, Edward J