Preictal dysfunctions of inhibitory interneurons paradoxically lead to their rebound hyperactivity and to low-voltage-fast onset seizures in Dravet syndrome
Dravet综合征中,抑制性中间神经元发作前功能障碍反而会导致其反弹性过度活跃,并引起低电压快速发作的癫痫。
期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2316364121
Capitano, Fabrizio; Kuchenbuch, Mathieu; Lavigne, Jennifer; Chaptoukaev, Hava; Zuluaga, Maria A; Lorenzi, Marco; Nabbout, Rima; Mantegazza, Massimo