日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Xeno-nucleic acids support formation of Ag(I)-mediated duplexes and silver nanoclusters

异源核酸促进Ag(I)介导的双链体和银纳米簇的形成

Guha, Rweetuparna; Bethur, Eshana; Chim, Nicholas; Gupta, Manoj K; Lin, I-Hsin; Taylor, Rebecca E; Chaput, John C; Copp, Stacy M

Allele-specific knockdown by an engineered DNAzyme capable of RNase H1 evasion.

利用经过改造的DNA酶进行等位基因特异性敲低,该DNA酶能够逃避RNase H1的攻击。

Lee Erica M, Nguyen Kim, Setterholm Noah A, Malik Turnee N, Chaput John C

Directed evolution of a TNA polymerase identifies independent paths to fidelity and catalysis

TNA聚合酶的定向进化揭示了实现保真性和催化作用的独立途径

Hajjar, Mohammad; Maola, Victoria A; Lee, Joy J; Holguin, Manuel J; Quijano, Riley N; Nguyen, Kalvin K; Ho, Katherine L; Medina, Jenny V; Botello-Cornejo, Elionel; Barpuzary, Bhawna; Chim, Nicholas; Chaput, John C

Measuring XNA polymerase fidelity in a hydrogel particle format

在水凝胶颗粒形式中测量 XNA 聚合酶的保真度

Medina, Esau L; Chaput, John C

The XNA alphabet

XNA字母表

Chaput, John C; Egli, Martin; Herdewijn, Piet

Chemical evolution of ASO-like DNAzymes for effective and extended gene silencing in cells.

利用化学方法进化 ASO 样 DNA 酶,实现细胞内有效且持久的基因沉默

Liu Yingyu, Zhang Sheyu, Zhang Meiqi, Liu Xin, Wu Yashu, Wu Qin, Chaput John C, Wang Yajun

Improved synthesis and polymerase recognition of 7-deaza-7-modified α-l-threofuranosyl guanosine analogs

改进的 7-脱氮-7-修饰的 α-L-苏式呋喃糖基鸟苷类似物的合成和聚合酶识别

Barpuzary, Bhawna; Negria, Sergey; Chaput, John C

Increasing the functional density of threose nucleic acid

提高苏糖核酸的功能密度

Majumdar, Biju; Sarma, Daisy; Yu, Yutong; Lozoya-Colinas, Adriana; Chaput, John C

DNA Replication across α-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase η

人类DNA聚合酶η介导的跨越α-l-(3'-2')-苏式呋喃糖核苷酸的DNA复制

Tomar, Rachana; Ghodke, Pratibha P; Patra, Amritraj; Smyth, Elizabeth; Pontarelli, Alexander; Copp, William; Guengerich, F Peter; Chaput, John C; Wilds, Christopher J; Stone, Michael P; Egli, Martin

Functionally Enhanced XNA Aptamers Discovered by Parallelized Library Screening

通过并行文库筛选发现功能增强型XNA适体

Lozoya-Colinas, Adriana; Yu, Yutong; Chaput, John C