日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

A first-in-class EGFR-directed KRAS G12V selective inhibitor

首创的EGFR靶向KRAS G12V选择性抑制剂

Lyla J Stanland ,Hayden P Huggins ,Snehasudha S Sahoo ,Alessandro Porrello ,Yogitha Chareddy ,Salma H Azam ,Jillian L Perry ,Pradeep S Pallan ,Kristina Whately ,Lincy Edatt ,William D Green ,Matthew C Fleming ,Jonah Im ,Christina Gutierrez-Ford ,Imani Simmons ,Alyaa Dawoud ,Katherine I Zhou ,Vandanaa Jayaprakash ,Rani S Sellers ,Gabriela de la Cruz ,Albert Wielgus ,Justin Milner ,Martin Egli ,Albert A Bowers ,Chad V Pecot

Inverted chimeric RNAi molecules synergistically cotarget MYC and KRAS in KRAS-driven cancers

反向嵌合RNAi分子协同靶向KRAS驱动的癌症中的MYC和KRAS

Chareddy, Yogitha S; Huggins, Hayden P; Sahoo, Snehasudha S; Stanland, Lyla J; Gutierrez-Ford, Christina; Whately, Kristina M; Edatt, Lincy; Azam, Salma H; Fleming, Matthew C; Im, Jonah; Porrello, Alessandro; Simmons, Imani; Perry, Jillian L; Bowers, Albert A; Egli, Martin; Pecot, Chad V

An integrated model for predicting KRAS dependency

用于预测 KRAS 依赖性的集成模型

Tsai, Yihsuan S; Chareddy, Yogitha S; Price, Brandon A; Parker, Joel S; Pecot, Chad V

TLR4 signaling and macrophage inflammatory responses are dampened by GIV/Girdin

GIV/Girdin可抑制TLR4信号传导和巨噬细胞炎症反应。

Swanson, Lee; Katkar, Gajanan D; Tam, Julian; Pranadinata, Rama F; Chareddy, Yogitha; Coates, Jane; Anandachar, Mahitha Shree; Castillo, Vanessa; Olson, Joshua; Nizet, Victor; Kufareva, Irina; Das, Soumita; Ghosh, Pradipta