Itaconate drives mtRNA-mediated type I interferon production through inhibition of succinate dehydrogenase.
衣康酸通过抑制琥珀酸脱氢酶来驱动 mtRNA 介导的 I 型干扰素的产生
期刊:Nature Metabolism
影响因子:20.8
doi:10.1038/s42255-024-01145-1
O'Carroll Shane M, Peace Christian G, Toller-Kawahisa Juliana E, Min Yukun, Hooftman Alexander, Charki Sara, Kehoe Louise, O'Sullivan Maureen J, Zoller Aline, Mcgettrick Anne F, Zotta Alessia, Day Emily A, Simarro Maria, Armstrong Neali, Annes Justin P, O'Neill Luke A J
