日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Cardiac Troponin C E135A Variant Impairs Myofilament Response to PKA Phosphorylation and Is Associated With Autosomal Dominant Dilated Cardiomyopathy With Diastolic Dysfunction

心肌肌钙蛋白C E135A变异体损害肌丝对PKA磷酸化的反应,并与常染色体显性遗传性扩张型心肌病伴舒张功能障碍相关。

Landim-Vieira, Maicon; Perelli, Robin M; Rodriguez-Garcia, Michelle; Jani, Vivek P; Chastain, Ronnie C; Lamar, Joshua H; Mines, Ellen; Seo, Gwimoon; Araujo Fernandes, Aurelia; Knollmann, Bjorn; Carboni, Michael P; Chelko, Stephen P; Galkin, Vitold E; Chase, P Bryant; Pinto, Jose Renato; Landstrom, Andrew P

The role of the troponin T interactions with actin in regulation of cardiac thin filament revealed by the troponin T pathogenic variant Ile79Asn

肌钙蛋白T致病变异体Ile79Asn揭示了肌钙蛋白T与肌动蛋白相互作用在调节心肌细丝中的作用

Risi, Cristina M; Landim-Vieira, Maicon; Belknap, Betty; Chase, P Bryant; Pinto, Jose R; Galkin, Vitold E

Desmoglein-2 deficiency results in cardiac dysfunction by compromising both Z-disc- and intercalated disc-mediated mechanotransduction

桥粒芯蛋白-2缺乏会损害Z盘和闰盘介导的机械转导,从而导致心脏功能障碍。

Landim-Vieira, Maicon; Jani, Vivek P; Shiel, Emily; Rastegarpouyani, Hosna; Engel, Morgan; Paradine, Flair; Chastain, Ronnie; Farra, Waleed; Ma, Weikang; Toepfer, Christopher; Chase, P Bryant; Kass, David A; Pinto, J Renato; Chelko, Stephen P

Post-translational modifications of vertebrate striated muscle myosin heavy chains

脊椎动物横纹肌肌球蛋白重链的翻译后修饰

Morales, Paula Nieto; Coons, Arianna N; Koopman, Amelia J; Patel, Sonu; Chase, P Bryant; Parvatiyar, Michelle S; Pinto, Jose R

High-resolution cryo-EM structure of the junction region of the native cardiac thin filament in relaxed state

高分辨率冷冻电镜结构显示,天然心肌细丝在松弛状态下的连接区域

Risi, Cristina M; Belknap, Betty; White, Howard D; Dryden, Kelly; Pinto, Jose R; Chase, P Bryant; Galkin, Vitold E

Post-translational modification patterns on β-myosin heavy chain are altered in ischemic and nonischemic human hearts

缺血性和非缺血性人类心脏中β-肌球蛋白重链的翻译后修饰模式发生改变

Landim-Vieira, Maicon; Childers, Matthew C; Wacker, Amanda L; Garcia, Michelle Rodriquez; He, Huan; Singh, Rakesh; Brundage, Elizabeth A; Johnston, Jamie R; Whitson, Bryan A; Chase, P Bryant; Janssen, Paul M L; Regnier, Michael; Biesiadecki, Brandon J; Pinto, J Renato; Parvatiyar, Michelle S

A comprehensive guide to genetic variants and post-translational modifications of cardiac troponin C

心肌肌钙蛋白C的遗传变异和翻译后修饰的综合指南

Reinoso, Tyler R; Landim-Vieira, Maicon; Shi, Yun; Johnston, Jamie R; Chase, P Bryant; Parvatiyar, Michelle S; Landstrom, Andrew P; Pinto, Jose R; Tadros, Hanna J

Meta-analysis of cardiomyopathy-associated variants in troponin genes identifies loci and intragenic hot spots that are associated with worse clinical outcomes

对肌钙蛋白基因中与心肌病相关的变异进行荟萃分析,可识别出与不良临床结局相关的基因位点和基因内热点区域。

Tadros, Hanna J; Life, Chelsea S; Garcia, Gustavo; Pirozzi, Elisa; Jones, Edward G; Datta, Susmita; Parvatiyar, Michelle S; Chase, P Bryant; Allen, Hugh D; Kim, Jeffrey J; Pinto, Jose R; Landstrom, Andrew P

Cardiomyocyte nuclearity and ploidy: when is double trouble?

心肌细胞核数和倍性:何时会出现双重问题?

Landim-Vieira, Maicon; Schipper, Joslyn M; Pinto, J Renato; Chase, P Bryant

Familial Dilated Cardiomyopathy Associated With a Novel Combination of Compound Heterozygous TNNC1 Variants

与新型复合杂合TNNC1变异组合相关的家族性扩张型心肌病

Landim-Vieira, Maicon; Johnston, Jamie R; Ji, Weizhen; Mis, Emily K; Tijerino, Joshua; Spencer-Manzon, Michele; Jeffries, Lauren; Hall, E Kevin; Panisello-Manterola, David; Khokha, Mustafa K; Deniz, Engin; Chase, P Bryant; Lakhani, Saquib A; Pinto, Jose Renato