Anti-4-1BB immunotherapy enhances systemic immune effects of radiotherapy to induce B and T cell-dependent anti-tumor immune activation and improve tumor control at unirradiated sites
抗 4-1BB 免疫疗法可增强放射治疗的全身免疫作用,从而诱导 B 细胞和 T 细胞依赖性抗肿瘤免疫激活并改善未受照射部位的肿瘤控制
期刊:Cancer Immunology Immunotherapy
影响因子:8.1
doi:10.1007/s00262-022-03325-y
Alexandra L Martin #, Chase Powell #, Mate Z Nagy, Patrick Innamarato, John Powers, Derek Nichols, Carmen M Anadon, Ricardo A Chaurio, Sungjune Kim, Min-Hsuan Wang, Bing Gong, Xianzhe Wang, Thomas J Scheutz, Scott J Antonia, Jose R Conejo-Garcia, Bradford A Perez
肿瘤
B细胞
T细胞
Functional/Block/Neutralize
Mouse
TNFRSF9