日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Exploration of a Large Virtual Chemical Space: Identification of Potent Inhibitors of Lactate Dehydrogenase-A against Pancreatic Cancer

探索大型虚拟化学空间:鉴定抗胰腺癌的强效乳酸脱氢酶A抑制剂

Horrick Sharma ,Pragya Sharma ,Uzziah Urquiza ,Lerin R Chastain ,Michael A Ihnat

Talimogene Laherparepvec in Combination With Ipilimumab in Previously Untreated, Unresectable Stage IIIB-IV Melanoma

Talimogene Laherparepvec 与 Ipilimumab 联合用于既往未接受治疗的不可切除的 IIIB-IV 期黑色素瘤

Puzanov, Igor; Milhem, Mohammed M; Minor, David; Hamid, Omid; Li, Ai; Chen, Lisa; Chastain, Michael; Gorski, Kevin S; Anderson, Abraham; Chou, Jeffrey; Kaufman, Howard L; Andtbacka, Robert H I

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors

RAS通路依赖性的基因表达特征可预测对PI3K和RAS通路抑制剂的反应,并扩大RAS通路激活肿瘤的群体。

Loboda, Andrey; Nebozhyn, Michael; Klinghoffer, Rich; Frazier, Jason; Chastain, Michael; Arthur, William; Roberts, Brian; Zhang, Theresa; Chenard, Melissa; Haines, Brian; Andersen, Jannik; Nagashima, Kumiko; Paweletz, Cloud; Lynch, Bethany; Feldman, Igor; Dai, Hongyue; Huang, Pearl; Watters, James

Distinct expression profiles of Notch-1 protein in human solid tumors: Implications for development of targeted therapeutic monoclonal antibodies.

Notch-1 蛋白在人类实体瘤中的独特表达谱:对靶向治疗性单克隆抗体开发的意义

Li Yuan, Burns Janine A, Cheney Carol A, Zhang Ningyan, Vitelli Salvatore, Wang Fubao, Bett Andrew, Chastain Michael, Audoly Laurent P, Zhang Zhi-Qiang

An oligosaccharide-based HIV-1 2G12 mimotope vaccine induces carbohydrate-specific antibodies that fail to neutralize HIV-1 virions

一种基于寡糖的HIV-1 2G12模拟表位疫苗会诱导产生碳水化合物特异性抗体,这些抗体无法中和HIV-1病毒颗粒。

Joyce, Joseph G; Krauss, Isaac J; Song, Hong C; Opalka, David W; Grimm, Karen M; Nahas, Deborah D; Esser, Mark T; Hrin, Renee; Feng, Meizhen; Dudkin, Vadim Y; Chastain, Michael; Shiver, John W; Danishefsky, Samuel J

Universal influenza B vaccine based on the maturational cleavage site of the hemagglutinin precursor

基于血凝素前体成熟裂解位点的通用型B型流感疫苗

Bianchi, Elisabetta; Liang, Xiaoping; Ingallinella, Paolo; Finotto, Marco; Chastain, Michael A; Fan, Jiang; Fu, Tong-Ming; Song, Hong Chang; Horton, Melanie S; Freed, Daniel C; Manger, Walter; Wen, Emily; Shi, Li; Ionescu, Roxana; Price, Colleen; Wenger, Marc; Emini, Emilio A; Cortese, Riccardo; Ciliberto, Gennaro; Shiver, John W; Pessi, Antonello

Heterologous human immunodeficiency virus type 1 priming-boosting immunization strategies involving replication-defective adenovirus and poxvirus vaccine vectors

异源性人类免疫缺陷病毒1型启动-加强免疫策略,涉及复制缺陷型腺病毒和痘病毒疫苗载体

Casimiro, Danilo R; Bett, Andrew J; Fu, Tong-ming; Davies, Mary-Ellen; Tang, Aimin; Wilson, Keith A; Chen, Minchun; Long, Romnie; McKelvey, Troy; Chastain, Michael; Gurunathan, Sanjay; Tartaglia, Jim; Emini, Emilio A; Shiver, John