日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Pharmacological modulation of developmental and synaptic phenotypes in human SHANK3 deficient stem cell-derived neuronal models

药理学调控人类 SHANK3 缺陷干细胞衍生神经元模型的发育和突触表型

Thibaudeau, Amandine; Schmitt, Karen; François, Louise; Chatrousse, Laure; Hoffmann, David; Cousin, Loic; Weiss, Amélie; Vuidel, Aurore; Jacob, Christina B; Sommer, Peter; Benchoua, Alexandra; Wilbertz, Johannes H

Identification of signaling pathways modifying human dopaminergic neuron development using a pluripotent stem cell-based high-throughput screening automated system: purinergic pathways as a proof-of-principle

使用基于多能干细胞的高通量筛选自动化系统识别改变人类多巴胺能神经元发育的信号通路:嘌呤能通路作为原理证明

Claire Boissart, Marie Lasbareilles, Johana Tournois, Laure Chatrousse, Thifaine Poullion, Alexandra Benchoua

CRISPR/Cas9-mediated generation of human embryonic stem cell sub-lines with HPRT1 gene knockout to model Lesch Nyhan disease

CRISPR/Cas9 介导产生具有 HPRT1 基因敲除的人类胚胎干细胞亚系以模拟莱施·尼汉病

Claire Boissart, Laure Chatrousse, Thifaine Poullion, Lina El-Kassar, Karine Giraud-Triboult, Alexandra Benchoua

Rescuing compounds for Lesch-Nyhan disease identified using stem cell-based phenotypic screening

利用基于干细胞的表型筛选鉴定出治疗莱希-尼汉病的救援化合物

Valentin Ruillier, Johana Tournois, Claire Boissart, Marie Lasbareilles, Gurvan Mahé, Laure Chatrousse, Michel Cailleret, Marc Peschanski, Alexandra Benchoua

Human Pluripotent Stem Cell-derived Cortical Neurons for High Throughput Medication Screening in Autism: A Proof of Concept Study in SHANK3 Haploinsufficiency Syndrome

人类多能干细胞衍生的皮质神经元用于自闭症的高通量药物筛选:SHANK3 单倍体不足综合征的概念验证研究

Hélène Darville, Aurélie Poulet, Frédérique Rodet-Amsellem, Laure Chatrousse, Julie Pernelle, Claire Boissart, Delphine Héron, Caroline Nava, Anselme Perrier, Margot Jarrige, Francis Cogé, Mark J Millan, Thomas Bourgeron, Marc Peschanski, Richard Delorme, Alexandra Benchoua

In vitro modeling of hyperpigmentation associated to neurofibromatosis type 1 using melanocytes derived from human embryonic stem cells

使用源自人类胚胎干细胞的黑色素细胞体外模拟 1 型神经纤维瘤病相关的色素沉着

Jennifer Allouche, Nathalia Bellon, Manoubia Saidani, Laure Stanchina-Chatrousse, Yolande Masson, Anand Patwardhan, Floriane Gilles-Marsens, Cédric Delevoye, Sophie Domingues, Xavier Nissan, Cécile Martinat, Gilles Lemaitre, Marc Peschanski, Christine Baldeschi