日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Macrophage development and activation involve coordinated intron retention in key inflammatory regulators

巨噬细胞的发育和活化涉及关键炎症调节剂中内含子的协调保留

Immanuel D Green, Natalia Pinello, Renhua Song, Quintin Lee, James M Halstead, Chau-To Kwok, Alex C H Wong, Shalima S Nair, Susan J Clark, Ben Roediger, Ulf Schmitz, Mark Larance, Rippei Hayashi, John E J Rasko, Justin J-L Wong

Genetic alterations of m(6)A regulators predict poorer survival in acute myeloid leukemia

m(6)A调节因子的基因改变预示着急性髓系白血病患者生存率较低。

Kwok, Chau-To; Marshall, Amy D; Rasko, John E J; Wong, Justin J L

Erratum to: Genetic alterations of m(6)A regulators predict poorer survival in acute myeloid leukemia

更正:m(6)A调节因子的基因改变预示急性髓系白血病患者生存率较差

Kwok, Chau-To; Marshall, Amy D; Rasko, John E J; Wong, Justin J L

Intron retention is regulated by altered MeCP2-mediated splicing factor recruitment

内含子保留受 MeCP2 介导的剪接因子募集改变的调控。

Justin J-L Wong ,Dadi Gao ,Trung V Nguyen ,Chau-To Kwok ,Michelle van Geldermalsen ,Rob Middleton ,Natalia Pinello ,Annora Thoeng ,Rajini Nagarajah ,Jeff Holst ,William Ritchie ,John E J Rasko

Lynch syndrome associated with two MLH1 promoter variants and allelic imbalance of MLH1 expression

林奇综合征与两种MLH1启动子变异和MLH1表达等位基因失衡相关

Hesson, Luke B; Packham, Deborah; Kwok, Chau-To; Nunez, Andrea C; Ng, Benedict; Schmidt, Christa; Fields, Michael; Wong, Jason W H; Sloane, Mathew A; Ward, Robyn L

The MLH1 c.-27C>A and c.85G>T variants are linked to dominantly inherited MLH1 epimutation and are borne on a European ancestral haplotype

MLH1 c.-27C>A 和 c.85G>T 变异与显性遗传的 MLH1 表观突变相关,并且存在于欧洲祖先单倍型上。

Kwok, Chau-To; Vogelaar, Ingrid P; van Zelst-Stams, Wendy A; Mensenkamp, Arjen R; Ligtenberg, Marjolijn J; Rapkins, Robert W; Ward, Robyn L; Chun, Nicolette; Ford, James M; Ladabaum, Uri; McKinnon, Wendy C; Greenblatt, Marc S; Hitchins, Megan P

De novo constitutional MLH1 epimutations confer early-onset colorectal cancer in two new sporadic Lynch syndrome cases, with derivation of the epimutation on the paternal allele in one

在两例新发现的散发性林奇综合征病例中,新生MLH1表观遗传突变导致早发性结直肠癌,其中一例的表观遗传突变来源于父系等位基因。

Goel, Ajay; Nguyen, Thuy-Phuong; Leung, Hon-Chiu E; Nagasaka, Takeshi; Rhees, Jennifer; Hotchkiss, Erin; Arnold, Mildred; Banerji, Pia; Koi, Minoru; Kwok, Chau-To; Packham, Deborah; Lipton, Lara; Boland, C Richard; Ward, Robyn L; Hitchins, Megan P