日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Genetic effects on chromatin accessibility uncover mechanisms of liver gene regulation and quantitative traits

遗传因素对染色质可及性的影响揭示了肝脏基因调控和数量性状的机制

Currin, Kevin W; Perrin, Hannah J; Pandey, Gautam K; Alkhawaja, Abdalla A; Vadlamudi, Swarooparani; Musser, Annie E; Etheridge, Amy S; Broadaway, K Alaine; Rosen, Jonathan D; Varshney, Arushi; Chaudhry, Amarjit S; Gallins, Paul J; Wright, Fred A; Zhou, Yi-Hui; Parker, Stephen C J; Raffield, Laura M; Schuetz, Erin G; Innocenti, Federico; Mohlke, Karen L

Hepatic Abundance and Activity of Androgen- and Drug-Metabolizing Enzyme UGT2B17 Are Associated with Genotype, Age, and Sex

肝脏中雄激素和药物代谢酶UGT2B17的丰度和活性与基因型、年龄和性别相关

Bhatt, Deepak Kumar; Basit, Abdul; Zhang, Haeyoung; Gaedigk, Andrea; Lee, Seung-Been; Claw, Katrina G; Mehrotra, Aanchal; Chaudhry, Amarjit Singh; Pearce, Robin E; Gaedigk, Roger; Broeckel, Ulrich; Thornton, Timothy A; Nickerson, Deborah A; Schuetz, Erin G; Amory, John K; Leeder, J Steven; Prasad, Bhagwat

Polymorphic Human Sulfotransferase 2A1 Mediates the Formation of 25-Hydroxyvitamin D(3)-3-O-Sulfate, a Major Circulating Vitamin D Metabolite in Humans.

多态性人类磺基转移酶 2A1 介导 25-羟基维生素 D(3)-3-O-硫酸盐的形成,这是人体内主要的循环维生素 D 代谢物

Wong Timothy, Wang Zhican, Chapron Brian D, Suzuki Mizuki, Claw Katrina G, Gao Chunying, Foti Robert S, Prasad Bhagwat, Chapron Alenka, Calamia Justina, Chaudhry Amarjit, Schuetz Erin G, Horst Ronald L, Mao Qingcheng, de Boer Ian H, Thornton Timothy A, Thummel Kenneth E

Interindividual Variability in Cytochrome P450-Mediated Drug Metabolism

细胞色素P450介导的药物代谢的个体间差异

Tracy, Timothy S; Chaudhry, Amarjit S; Prasad, Bhagwat; Thummel, Kenneth E; Schuetz, Erin G; Zhong, Xiao-Bo; Tien, Yun-Chen; Jeong, Hyunyoung; Pan, Xian; Shireman, Laura M; Tay-Sontheimer, Jessica; Lin, Yvonne S

The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles

CYP2C19 内含子 2 分支点 SNP 是导致携带 CYP2C19*35 和 CYP2C19*2 等位基因的肝脏出现代谢不良表型的祖先多态性。

Chaudhry, Amarjit S; Prasad, Bhagwat; Shirasaka, Yoshiyuki; Fohner, Alison; Finkelstein, David; Fan, Yiping; Wang, Shuoguo; Wu, Gang; Aklillu, Eleni; Sim, Sarah C; Thummel, Kenneth E; Schuetz, Erin G

In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.

利用 MDR1-荧光素酶报告基因小鼠对大脑和脊髓中人类 MDR1 转录进行体内成像

Yasuda Kazuto, Cline Cynthia, Lin Yvonne S, Scheib Rachel, Ganguly Samit, Thirumaran Ranjit K, Chaudhry Amarjit, Kim Richard B, Schuetz Erin G

Why do most human liver cytosol preparations lack xanthine oxidase activity?

为什么大多数人肝细胞溶胶制剂缺乏黄嘌呤氧化酶活性?

Barr, John T; Choughule, Kanika V; Nepal, Sahadev; Wong, Timothy; Chaudhry, Amarjit S; Joswig-Jones, Carolyn A; Zientek, Michael; Strom, Stephen C; Schuetz, Erin G; Thummel, Kenneth E; Jones, Jeffrey P

Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3: metabolite structure, kinetics, inducibility, and interindividual variability

人 UGT1A4 和 UGT1A3 结合物 25-羟基维生素 D3:代谢物结构、动力学、诱导性和个体间差异

Wang, Zhican; Wong, Timothy; Hashizume, Takanori; Dickmann, Leslie Z; Scian, Michele; Koszewski, Nicholas J; Goff, Jesse P; Horst, Ronald L; Chaudhry, Amarjit S; Schuetz, Erin G; Thummel, Kenneth E

Regulation of coagulation factor XI expression by microRNAs in the human liver

人肝脏中microRNA对凝血因子XI表达的调控

Salloum-Asfar, Salam; Teruel-Montoya, Raúl; Arroyo, Ana B; García-Barberá, Nuria; Chaudhry, Amarjit; Schuetz, Erin; Luengo-Gil, Ginés; Vicente, Vicente; González-Conejero, Rocío; Martínez, Constantino

Hepatic organic anion transporting polypeptide transporter and thyroid hormone receptor interplay determines cholesterol and glucose homeostasis

肝脏有机阴离子转运多肽转运蛋白与甲状腺激素受体的相互作用决定胆固醇和葡萄糖的稳态

Meyer zu Schwabedissen, Henriette E; Ware, Joseph A; Finkelstein, David; Chaudhry, Amarjit S; Mansell, Sara; Leon-Ponte, Matilde; Strom, Stephen C; Zaher, Hani; Schwarz, Ute I; Freeman, David J; Schuetz, Erin G; Tirona, Rommel G; Kim, Richard B