日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Optimizing Tedizolid Dosing in Cerebral Nocardiosis: Clinical Impact of Direct Unbound Concentration Measurement and Population PK Modelling in Two Cases

优化特地唑胺在脑诺卡氏菌病中的给药方案:直接游离浓度测定和群体药代动力学模型在两例病例中的临床意义

Marc-Olivier, Vareil; Margaux, Bouet; David, Leyssene; Anne Christine, Jaouen; Heidi, Wille; Christophe, Adier; Laure, Alleman; Alexia, Chauzy

In vitro pharmacokinetic/pharmacodynamic modeling of the effect of mucin on polymyxin B activity against Acinetobacter baumannii

体外药代动力学/药效学模型研究粘蛋白对多粘菌素B抗鲍曼不动杆菌活性的影响

Lacroix, Mathilde; Moreau, Jérémy; Zampaloni, Claudia; Bissantz, Caterina; Mirfendereski, Hélène; Shirvani, Hamasseh; Marchand, Sandrine; Couet, William; Chauzy, Alexia

PKPD modeling of the inoculum effect of combined ceftazidime/avibactam and colistin against KPC-3 Klebsiella pneumoniae isolate

对头孢他啶/阿维巴坦和粘菌素联合用药对KPC-3肺炎克雷伯菌分离株的接种效应进行PKPD建模

Aubry, Romain; Buyck, Julien M; Chauzy, Alexia; Prouvensier, Laure; Decousser, Jean-Winoc; Nordmann, Patrice; Wicha, Sebastian G; Marchand, Sandrine; Grégoire, Nicolas

A hollow fiber infection model to study intracellular and extracellular antibiotic activity against Staphylococcus aureus

利用中空纤维感染模型研究针对金黄色葡萄球菌的细胞内和细胞外抗生素活性

Mahieu, Gwenaëlle; Elens, Laure; Prebonnaud, Noémie; Chauzy, Alexia; Van Bambeke, Françoise

A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data

一种易于获取、可灵活调整的中空纤维装置,用于重现一级吸收:以利奈唑胺脑脊液药代动力学数据为例

Prébonnaud, N; Chauzy, A; Grégoire, N; Dahyot-Fizelier, C; Adier, C; Marchand, S; Aranzana-Climent, V

A Minimal Physiologically Based Pharmacokinetic Model to Characterize CNS Distribution of Metronidazole in Neuro Care ICU Patients

基于生理学的最小药代动力学模型用于表征神经重症监护病房患者中甲硝唑的中枢神经系统分布

Chauzy, Alexia; Bouchène, Salim; Aranzana-Climent, Vincent; Clarhaut, Jonathan; Adier, Christophe; Grégoire, Nicolas; Couet, William; Dahyot-Fizelier, Claire; Marchand, Sandrine

A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

一种新的药代动力学-药效学模型用于表征鲍曼不动杆菌接种物对多粘菌素B的体外效应

Akrong, Grace; Chauzy, Alexia; Aranzana-Climent, Vincent; Lacroix, Mathilde; Deroche, Luc; Prouvensier, Laure; Buyck, Julien M; Couet, William; Marchand, Sandrine

Improved In Vitro Anti- Mucorales Activity and Cytotoxicity of Amphotericin B with a Pegylated Surfactant

聚乙二醇化表面活性剂可提高两性霉素 B 的体外抗毛霉活性和细胞毒性

Kévin Brunet, Cheikh A B Diop, Alexia Chauzy, Noémie Prébonnaud, Sandrine Marchand, Blandine Rammaert, Frédéric Tewes

Sequential Time-Kill, a Simple Experimental Trick To Discriminate between Pharmacokinetics/Pharmacodynamics Models with Distinct Heterogeneous Subpopulations versus Homogenous Population with Adaptive Resistance

序贯时间杀伤法:一种简单的实验技巧,可用于区分具有明显异质亚群的药代动力学/药效动力学模型与具有适应性耐药性的同质群体。

Chauzy, A; Ih, H; Jacobs, M; Marchand, S; Grégoire, N; Couet, W; Buyck, J M

Semimechanistic Pharmacodynamic Modeling of Aztreonam-Avibactam Combination to Understand Its Antimicrobial Activity Against Multidrug-Resistant Gram-Negative Bacteria

利用半机制药效学模型研究氨曲南-阿维巴坦联合用药对多重耐药革兰氏阴性菌的抗菌活性

Chauzy, Alexia; Gaelzer Silva Torres, Bruna; Buyck, Julien; de Jonge, Boudewijn; Adier, Christophe; Marchand, Sandrine; Couet, William; Grégoire, Nicolas