日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Durability of efficacy, safety, and quality of life 5 years after valoctocogene roxaparvovec gene transfer for severe hemophilia A: final phase 3 GENEr8-1 trial results

接受valoctocogene roxaparvovec基因转移治疗重度A型血友病5年后,疗效、安全性和生活质量的持久性:GENEr8-1 III期临床试验的最终结果

Leavitt, Andrew D; Mahlangu, Johnny; Raheja, Priyanka; Symington, Emily; Quon, Doris V; Giermasz, Adam; Kenet, Gili; Lowe, Gillian; Key, Nigel S; Millar, Carolyn M; Pipe, Steven W; Chou, Sheng-Chieh; Klamroth, Robert; Mason, Jane; Chambost, Hervé; Peyvandi, Flora; Majerus, Elaine; Pepperell, Dominic; Tan, Chee Wee; Yu, Hua; Chavele, Konstantia-Maria; Ozelo, Margareth C

Outcomes and management of invasive procedures in participants with hemophilia A post gene therapy: a post hoc analysis of the GENEr8-1 phase III trial

基因治疗后A型血友病患者侵入性操作的结局和管理:GENEr8-1 III期试验的事后分析

Quon, Doris V; Wang, Jiaan-Der; Wang, Michael; Pepperell, Dominic; Park, Young-Shil; Kenet, Gili; Mahlangu, Johnny; Khoo, Teh-Liane; Robinson, Tara M; Chavele, Konstantia-Maria; Pipe, Steven W

Reduced CD27-IgD- B Cells in Blood and Raised CD27-IgD- B Cells in Gut-Associated Lymphoid Tissue in Inflammatory Bowel Disease

炎症性肠病患者血液中的 CD27-IgD- B 细胞减少,肠道相关淋巴组织中的 CD27-IgD- B 细胞增多

Chathyan Pararasa, Na Zhang, Thomas J Tull, Ming H A Chong, Jacqueline H Y Siu, William Guesdon, Konstantia Maria Chavele, Jeremy D Sanderson, Louise Langmead, Klaartje Kok, Jo Spencer, Anna Vossenkamper

Spatiotemporal segregation of human marginal zone and memory B cell populations in lymphoid tissue

人类边缘区和记忆B细胞群在淋巴组织中的时空分离

Zhao, Yuan; Uduman, Mohamed; Siu, Jacqueline H Y; Tull, Thomas J; Sanderson, Jeremy D; Wu, Yu-Chang Bryan; Zhou, Julian Q; Petrov, Nedyalko; Ellis, Richard; Todd, Katrina; Chavele, Konstantia-Maria; Guesdon, William; Vossenkamper, Anna; Jassem, Wayel; D'Cruz, David P; Fear, David J; John, Susan; Scheel-Toellner, Dagmar; Hopkins, Claire; Moreno, Estefania; Woodman, Natalie L; Ciccarelli, Francesca; Heck, Susanne; Kleinstein, Steven H; Bemark, Mats; Spencer, Jo

Cutting edge: circulating plasmablasts induce the differentiation of human T follicular helper cells via IL-6 production

前沿:循环浆母细胞通过产生 IL-6 诱导人类 T 滤泡辅助细胞分化

Konstantia-Maria Chavele, Eve Merry, Michael R Ehrenstein

Leukocyte and serum S100A8/S100A9 expression reflects disease activity in ANCA-associated vasculitis and glomerulonephritis

白细胞和血清中S100A8/S100A9的表达反映了ANCA相关性血管炎和肾小球肾炎的疾病活动度。

Pepper, Ruth J; Hamour, Sally; Chavele, Konstantia-Maria; Todd, Sarah K; Rasmussen, Niels; Flint, Shaun; Lyons, Paul A; Smith, Kenneth G C; Pusey, Charles D; Cook, H Terence; Salama, Alan D

Mannose receptor interacts with Fc receptors and is critical for the development of crescentic glomerulonephritis in mice.

甘露糖受体与 Fc 受体相互作用,对小鼠新月体肾小球肾炎的发展至关重要

Chavele Konstantia-Maria, Martinez-Pomares Luisa, Domin Jan, Pemberton Samantha, Haslam Stuart M, Dell Anne, Cook H Terence, Pusey Charles D, Gordon Siamon, Salama Alan D