Chavkin相关文献与解析，生知库 | 链接生命科学的每一步

Demonstration and technoeconomic analysis of dodecanol production from acetate using metabolically engineered Escherichia coli

利用代谢工程改造的大肠杆菌从乙酸生产十二醇的示范和技术经济分析

doi:10.1016/j.ymben.2025.10.007

Perkovich, Paul M; Cortés-Peña, Yoel R; Baerwald, Justin J; Graupmann, Thomas H; Chavkin, Theodore A; Mishra, Shivangi; Cordell, William T; Zavala, Victor M; Pfleger, Brian F

代谢

发表日期：2026

文献求助收藏

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

造血系统中Y染色体的丢失会激活免疫检查点，并导致衰老细胞清除受损和肾脏疾病。

期刊:Science Translational Medicine

影响因子:15.8

doi:10.1126/scitranslmed.adv4071

Yohei Arai ，Nicholas W Chavkin ，Yuka Arai ，Jonatan Halvardson ，Josefin Bjurling ，Heather Doviak ，Jesse D Cochran ，Megan A Evans ，Keita Horitani ，Yoshimitsu Yura ，Emiri Miura-Yura ，Soichi Sano ，Lars A Forsberg ，Kenneth Walsh

Emergence of endothelial subtypes and role of cell cycle control in arterial-venous specification during embryonic vascular development.

内皮细胞亚型的出现以及细胞周期控制在胚胎血管发育过程中动静脉分化中的作用。

期刊:Cell Reports

影响因子:6.9

doi:10.1016/j.celrep.2025.116368

Aragon Jordon W, Nelson Elizabeth A, Chavkin Nicholas W, Jackson Madeline G, Heo Won, Cain Shelby R, Markowska Zaneta, Bradecamp Grace E, Genet Gael, Äwiek Aleksandra, Hirschi Karen K

Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice.

早产会增加雄性小鼠对高血糖诱发的肾小球病变的易感性

期刊:Scientific Reports

影响因子:3.9

doi:10.1038/s41598-025-00103-5

Cwiek Aleksandra, Dailey Rachel K, Kameshwar Ayyappa Kumar Sista, Suzuki Masako, Isaac Jaya, deRonde Kimberly, Conaway Mark, Bennett Kevin M, Baldelomar Edwin J, Li Teng, Wu Teresa, Hoch Matthew R, Chavkin Nicholas W, Walker Patrick D, Hirschi Karen K, Reidy Kimberly J, Charlton Jennifer R

发表日期：2025

文献求助收藏

Pain-related distress in children undergoing air enema reduction for ileocolic intussusception: a proof-of-concept case series

儿童回结肠套叠行空气灌肠复位术中的疼痛相关不适：概念验证病例系列研究

期刊:Pain Reports

影响因子:3.1

doi:10.1097/PR9.0000000000001327

Buchshtav, Nachshon; Ohana Sarna Cahan, Lea; Cohen, Neta; Chavkin, Maor; Shavit, Itai

发表日期：2025

文献求助收藏

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis.

血液中 Y 染色体的嵌合缺失与男性易患特发性肺纤维化有关

期刊:Commun Med (Lond)

影响因子:

doi:10.1038/s43856-025-00966-9

Bjurling Josefin, Chavkin Nicholas W, Halvardson Jonatan, Thel Mark C, Mattisson Jonas, Kim John S, Zaghlool Ammar, Ma Shwu-Fan, Martinez Fernando J, Anstrom Kevin, Noth Imre, Walsh Kenneth, Forsberg Lars A

其它

发表日期：2025

文献求助收藏

Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia

诱导内皮细胞周期阻滞可预防遗传性出血性毛细血管扩张症中的动静脉畸形

期刊:Circulation

影响因子:38.6

doi:10.1161/CIRCULATIONAHA.122.062952

Genet, Gael; Genet, Nafiisha; Paila, Umadevi; Cain, Shelby R; Cwiek, Aleksandra; Chavkin, Nicholas W; Serbulea, Vlad; Figueras, Agnès; Cerdà, Pau; McDonnell, Stephanie P; Sankaranarayanan, Danya; Huba, Mahalia; Nelson, Elizabeth A; Riera-Mestre, Antoni; Hirschi, Karen K

Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure

造血细胞中 Uty 表观遗传调节基因座的破坏表型复制了心力衰竭中 Y 染色体缺失的促纤维化特性

期刊:Nature Cardiovascular Research

影响因子:9.4

doi:10.1038/s44161-024-00441-z

Keita Horitani, Nicholas W Chavkin, Yohei Arai, Ying Wang, Hayato Ogawa, Yoshimitsu Yura, Megan A Evans, Jesse D Cochran, Mark C Thel, Ariel H Polizio, Miho Sano, Emiri Miura-Yura, Yuka Arai, Heather Doviak, Arthur P Arnold, Bradley D Gelfand, Karen K Hirschi, Soichi Sano, Kenneth Walsh

Tet2-mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke

Tet2介导的克隆性造血可轻微改善神经功能缺损，并与实验性卒中亚急性期的炎症消退相关。

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2024.1487867

Evans, Megan A; Chavkin, Nicholas W; Sano, Soichi; Sun, Hanna; Sardana, Taneesha; Ravi, Ramya; Doviak, Heather; Wang, Ying; Yura, Yoshimitsu; Polizio, Ariel H; Horitani, Keita; Ogawa, Hayato; Hirschi, Karen K; Walsh, Kenneth

G Protein Inactivation as a Mechanism for Addiction Treatment

G蛋白失活作为成瘾治疗的一种机制

Demonstration and technoeconomic analysis of dodecanol production from acetate using metabolically engineered Escherichia coli

利用代谢工程改造的大肠杆菌从乙酸生产十二醇的示范和技术经济分析

Hematopoietic loss of Y chromosome activates immune checkpoints and contributes to impaired senescent cell clearance and renal disease

造血系统中Y染色体的丢失会激活免疫检查点，并导致衰老细胞清除受损和肾脏疾病。

Emergence of endothelial subtypes and role of cell cycle control in arterial-venous specification during embryonic vascular development.

内皮细胞亚型的出现以及细胞周期控制在胚胎血管发育过程中动静脉分化中的作用。

Preterm birth increases susceptibility to hyperglycemia induced glomerular alterations in male mice.

早产会增加雄性小鼠对高血糖诱发的肾小球病变的易感性

Pain-related distress in children undergoing air enema reduction for ileocolic intussusception: a proof-of-concept case series

儿童回结肠套叠行空气灌肠复位术中的疼痛相关不适：概念验证病例系列研究

Mosaic loss of chromosome Y in blood is associated with male susceptibility for idiopathic pulmonary fibrosis.

血液中 Y 染色体的嵌合缺失与男性易患特发性肺纤维化有关

Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia

诱导内皮细胞周期阻滞可预防遗传性出血性毛细血管扩张症中的动静脉畸形

Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure

造血细胞中 Uty 表观遗传调节基因座的破坏表型复制了心力衰竭中 Y 染色体缺失的促纤维化特性

Tet2-mediated clonal hematopoiesis modestly improves neurological deficits and is associated with inflammation resolution in the subacute phase of experimental stroke

Tet2介导的克隆性造血可轻微改善神经功能缺损，并与实验性卒中亚急性期的炎症消退相关。