日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Explainable Physicochemical Determinants of Protein-Ligand Binding via Non-Covalent Interactions

通过非共价相互作用解释蛋白质-配体结合的可解释的物理化学决定因素

Meng, Zhaohan; Bai, Zhen; Yuan, Ke; Cheah, Jaime H; Jiang, Wei; Skepner, Adam; Leahy, Kevin J; Ounis, Iadh; Oldham, William M; Meng, Zaiqiao; Xu, Hao; Loscalzo, Joseph

Phenotypic screening converges on CDK9 inhibition as a therapeutic strategy in translocation renal cell carcinoma.

表型筛选结果表明,CDK9 抑制是易位性肾细胞癌的一种治疗策略

Thapa Dharma R, Deodhar Riva, Skepner Adam, Konda Prathyusha, Zhou Meng, Bluck Joseph, Pichlo Christian, Cui Yantong, Stocker Paige, Khanna Prateek, Li Jiao, Tsai Jonathan M, Leed Alison, Gould Sandy, Alimova Maria, Friedrich Dhana, Cheah Jaime H, Rupaimoole Rajesha, Guicherit Oivin, Viswanathan Srinivas R

Massively parallel pooled screening reveals genomic determinants of nanoparticle delivery

大规模并行混合筛选揭示了纳米颗粒递送的基因组决定因素

Boehnke, Natalie; Straehla, Joelle P; Safford, Hannah C; Kocak, Mustafa; Rees, Matthew G; Ronan, Melissa; Rosenberg, Danny; Adelmann, Charles H; Chivukula, Raghu R; Nabar, Namita; Berger, Adam G; Lamson, Nicholas G; Cheah, Jaime H; Li, Hojun; Roth, Jennifer A; Koehler, Angela N; Hammond, Paula T

Discovery of a Small-Molecule Probe for V-ATPase Function

发现一种用于检测V-ATPase功能的小分子探针

Aldrich, Leslie N; Kuo, Szu-Yu; Castoreno, Adam B; Goel, Gautam; Kuballa, Petric; Rees, Matthew G; Seashore-Ludlow, Brinton A; Cheah, Jaime H; Latorre, Isabel J; Schreiber, Stuart L; Shamji, Alykhan F; Xavier, Ramnik J

Concise Total Synthesis of (+)-Luteoalbusins A and B

(+)-黄素A和B的简明全合成

Adams, Timothy C; Payette, Joshua N; Cheah, Jaime H; Movassaghi, Mohammad

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules

一个用于识别小分子靶向的癌症遗传和谱系依赖性的交互式资源

Basu, Amrita; Bodycombe, Nicole E; Cheah, Jaime H; Price, Edmund V; Liu, Ke; Schaefer, Giannina I; Ebright, Richard Y; Stewart, Michelle L; Ito, Daisuke; Wang, Stephanie; Bracha, Abigail L; Liefeld, Ted; Wawer, Mathias; Gilbert, Joshua C; Wilson, Andrew J; Stransky, Nicolas; Kryukov, Gregory V; Dancik, Vlado; Barretina, Jordi; Garraway, Levi A; Hon, C Suk-Yee; Munoz, Benito; Bittker, Joshua A; Stockwell, Brent R; Khabele, Dineo; Stern, Andrew M; Clemons, Paul A; Shamji, Alykhan F; Schreiber, Stuart L