Mitochondrial SIRT3 Deficiency Results in Neuronal Network Hyperexcitability, Accelerates Age-Related Aβ Pathology, and Renders Neurons Vulnerable to Aβ Toxicity

线粒体 SIRT3 缺陷会导致神经元网络过度兴奋、加速与年龄相关的 Aβ 病理，并使神经元易受 Aβ 毒性影响