日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Integrated multi-omics identifies a CD54(+) iCAF-ITGAL(+) macrophage niche driving immunosuppression via CXCL8-PDL1 axis in cervical cancer

整合多组学分析发现，CD54(+) iCAF-ITGAL(+)巨噬细胞微环境通过CXCL8-PDL1轴驱动宫颈癌中的免疫抑制。

期刊:Molecular Cancer
影响因子:33.9
doi:10.1186/s12943-025-02471-y
Chen, Fanghua; Bai, Gaigai; Liu, Qinqin; He, Guangping; Ding, Ziyang; Liang, Jiali; Wang, Nan; Qiu, Junjun; Hua, Keqin
巨噬细胞
肿瘤
CD5
肿瘤免疫
巨噬细胞
CD54
宫颈癌
细胞生物学
CXCL8
免疫/内分泌
发表日期：2025
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Targeting Glutamine Metabolism Transporter SLC25A22 Enhances CD8+ T-Cell Function and Anti-PD-1 Therapy Efficacy in Cervical Squamous Cell Carcinoma: Integrated Metabolomics, Transcriptomics and T-Cell-Incorporated Tumor Organoid Studies.

靶向谷氨酰胺代谢转运蛋白 SLC25A22 可增强 CD8+ T 细胞功能和抗 PD-1 疗法在宫颈鳞状细胞癌中的疗效：整合代谢组学、转录组学和 T 细胞肿瘤类器官研究

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202502225
Ren Tingting, Qiu Junjun, Chen Fanghua, Jiang Qian, Liu Qinqin, Wu Tong, Jiang Hua, Hua Keqin
代谢
肿瘤
CD8
发表日期：2025
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Multi-omics dissection of tumor microenvironment-mediated drug resistance: mechanisms and therapeutic reprogramming

肿瘤微环境介导的耐药性的多组学解析：机制和治疗重编程

期刊:Frontiers in Pharmacology
影响因子:4.8
doi:10.3389/fphar.2025.1634413
Chen, Fanghua; Fu, Yuandong; Bai, Gaigai; Qiu, Junjun; Hua, Keqin
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2025
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Hierarchical spatio-temporal graph network for risk prediction

用于风险预测的分层时空图网络

期刊:Scientific Reports
影响因子:3.9
doi:10.1038/s41598-025-33873-z
Chen, Fanghua; Jia, Hong; Zhou, Wei; Zhu, Liwei; Xiao, Lin
发表日期：2025
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Machine learning-based prediction of clinical outcomes in cervical cancer using routine hematological indices: development and web implementation

基于机器学习的宫颈癌临床结局预测：利用常规血液学指标的开发和网络实现

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2025.1661153
Bai, Gaigai; Chen, Fanghua; Qiu, Junjun; Hua, Keqin
宫颈癌
肿瘤
肿瘤免疫
发表日期：2025
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Circadian Regulator-Mediated Molecular Subtypes Depict the Features of Tumor Microenvironment and Indicate Prognosis in Head and Neck Squamous Cell Carcinoma

昼夜节律调节因子介导的分子亚型描绘了头颈部鳞状细胞癌的肿瘤微环境特征并指示其预后

期刊:Journal of Immunology Research
影响因子:3.6
doi:10.1155/2023/9946911
Aye, Ling; Wang, Zhanying; Chen, Fanghua; Xiong, Yujun; Zhou, Jiaying; Wu, Feizhen; Hu, Li; Wang, Dehui
细胞生物学
肿瘤
肿瘤微环境
肿瘤免疫
发表日期：2023
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An integrative pan-cancer analysis of the molecular and biological features of glycosyltransferases

糖基转移酶分子和生物学特征的综合泛癌分析

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.872
Li, Yin; Lin, Youpei; Aye, Ling; Dong, Liangqing; Zhang, Chenhao; Chen, Fanghua; Liu, Yinkun; Fan, Jia; Gao, Qiang; Lu, Haojie; Lu, Chunlai; Zhang, Shu
肿瘤
肿瘤免疫
发表日期：2022
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Potential Biomarkers for Liver Cancer Diagnosis Based on Multi-Omics Strategy

基于多组学策略的肝癌诊断潜在生物标志物

期刊:Frontiers in Oncology
影响因子:3.3
doi:10.3389/fonc.2022.822449
Chen, Fanghua; Wang, Junming; Wu, Yingcheng; Gao, Qiang; Zhang, Shu
肿瘤
肝癌
肿瘤免疫
发表日期：2022
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Investigations on the Changes of Serum Proteins in Rabbits after Trimeresurus stejnegeri Venom Injection via Mass Spectrometry-Based Proteomics

基于质谱的蛋白质组学研究竹叶青毒注射后家兔血清蛋白质的变化

期刊:Evidence-Based Complementary and Alternative Medicine
影响因子:
doi:10.1155/2022/9239662
Shijun Wang, Weilian Yang, Wanling Shi, Fuwei Chen, Fanghua Shen, Meiji Zhang, Qiuxiang Su, Chao Shi, Qinyao Yu, Tao Chen
信号转导
Rabbit
发表日期：2022
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Quantification of Intact O-Glycopeptides on Haptoglobin in Sera of Patients With Hepatocellular Carcinoma and Liver Cirrhosis

肝细胞癌和肝硬化患者血清中完整O-糖肽与结合珠蛋白的定量分析

期刊:Frontiers in Chemistry
影响因子:4.2
doi:10.3389/fchem.2021.705341
Shu, Hong; Zhang, Lei; Chen, Yiwei; Guo, Yijie; Li, Limin; Chen, Fanghua; Cao, Zhao; Yan, Guoquan; Lu, Chunlai; Liu, Chao; Zhang, Shu
肝硬化
细胞生物学
肿瘤
肿瘤免疫
发表日期：2021
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