Chen Guoan相关文献与解析，生知库 | 链接生命科学的每一步

HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.

HDAC2介导的METTL3去乙酰化促进三阴性乳腺癌的DNA损伤修复和化疗耐药性

doi:10.1002/advs.202413121

He Xiaoniu, Li Yuanpei, Li Jian, Li Yu, Chen Sijie, Yan Xia, Xie Zhangrong, Du Jiangfeng, Chen Guoan, Song Jianbo, Mei Qi

GLUT1 sensitizes tumor cells to EGFR-TKIs by binding with activated EGFR and regulating its downstream signaling pathways.

GLUT1 通过与活化的 EGFR 结合并调节其下游信号通路，使肿瘤细胞对 EGFR-TKIs 敏感

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-025-02259-z

Xie Zhangrong, Zhou Zhiqing, Chen Sijie, Li Yu, He Xiaoniu, Chen Guoan

Silencing GGH induces autophagy by increasing folate stress and production of NADH

抑制GGH可通过增加叶酸应激和NADH的产生来诱导自噬。

期刊:Journal of Molecular Cell Biology

影响因子:5.9

doi:10.1093/jmcb/mjaf014

Li, Yu; Du, Yuhui; Chen, Sijie; Xie, Zhangrong; Li, Xinrui; Lin, Baoyue; Zhou, Zhiqing; Zhao, Huijie; Chen, Guoan

自噬

发表日期：2025

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PFKP silencing suppresses tumor growth via the AXL-MET axis

PFKP沉默通过AXL-MET轴抑制肿瘤生长

期刊:International Journal of Biological Sciences

影响因子:10

doi:10.7150/ijbs.100525

Zhao, Huijie; Sun, Yuze; Feng, Huijing; Cai, Jing; Liu, Yue; Li, Yu; Chen, Sijie; Zhou, Zhiqing; Du, Yuhui; Zeng, Xiaofei; Ren, Huan; Su, Wenmei; Mei, Qi; Chen, Guoan

Long-term outcomes with HLX01 (HanliKang(®)), a rituximab biosimilar, in previously untreated patients with diffuse large B-cell lymphoma: 5-year follow-up results of the phase 3 HLX01-NHL03 study

HLX01（韩利康®，一种利妥昔单抗生物类似药）治疗既往未接受治疗的弥漫性大B细胞淋巴瘤患者的长期疗效：3期HLX01-NHL03研究的5年随访结果

期刊:BMC Cancer

影响因子:3.4

doi:10.1186/s12885-024-11876-9

Qin, Yan; Song, Yongping; Wang, Dong; Bai, Ou; Feng, Jifeng; Sun, Xiuhua; Qiu, Lihua; Yang, Jianmin; Yang, Yu; Wang, Zhao; Hu, Jianda; Wang, Huaqing; Su, Hang; Jin, Zhengming; Qian, Wenbin; Jin, Chuan; Zhang, Mingzhi; Yu, Ding; Liu, Li; Chen, Guoan; Li, Yarong; Sun, Tao; Jin, Jie; Bao, Huizheng; Du, Xin; Zhou, Hui; Fu, Gan; Shi, Yuankai

Advances of HIF‑1α/glycolysis axis in non‑small cell lung cancer (Review)

非小细胞肺癌中 HIF-1α/糖酵解轴的研究进展（综述）

期刊:Gynecologic Oncology Reports

影响因子:1.3

doi:10.1016/j.gore.2024.101340

Lantsman, Taliya; Jia, Lily; Shea, Meghan; Shi, Yuxuan; Lin, Xiangyi; Wang, Jinwen; Zhou, Zhiqing; Chen, Sijie; Chen, Guoan

Iron and copper: critical executioners of ferroptosis, cuproptosis and other forms of cell death

铁和铜：铁死亡、铜死亡和其他形式细胞死亡的关键执行者

期刊:Cell Communication and Signaling

影响因子:8.9

doi:10.1186/s12964-023-01267-1

Li, Yu; Du, Yuhui; Zhou, Yujie; Chen, Qianhui; Luo, Zhijie; Ren, Yufan; Chen, Xudan; Chen, Guoan

Integrative analysis of multi-omics data reveals inhibition of RB1 signaling promotes apatinib resistance of hepatocellular carcinoma

多组学数据整合分析揭示RB1信号抑制促进肝细胞癌对阿帕替尼产生耐药性

期刊:International Journal of Biological Sciences

影响因子:8.2

doi:10.7150/ijbs.83862

Ke He, Sanqi An, Fei Liu, Ye Chen, Guoan Xiang, Haihe Wang

The GGH/HuR Complex Binds and Stabilizes mRNAs to Maintain Tumor Cell Cycle and DNA Replication

GGH/HuR复合物结合并稳定mRNA，从而维持肿瘤细胞周期和DNA复制

MicroRNA Gets a Mighty Award

微小RNA荣获大奖

HDAC2-Mediated METTL3 Delactylation Promotes DNA Damage Repair and Chemotherapy Resistance in Triple-Negative Breast Cancer.

HDAC2介导的METTL3去乙酰化促进三阴性乳腺癌的DNA损伤修复和化疗耐药性

GLUT1 sensitizes tumor cells to EGFR-TKIs by binding with activated EGFR and regulating its downstream signaling pathways.

GLUT1 通过与活化的 EGFR 结合并调节其下游信号通路，使肿瘤细胞对 EGFR-TKIs 敏感

Silencing GGH induces autophagy by increasing folate stress and production of NADH

抑制GGH可通过增加叶酸应激和NADH的产生来诱导自噬。

PFKP silencing suppresses tumor growth via the AXL-MET axis

PFKP沉默通过AXL-MET轴抑制肿瘤生长

Long-term outcomes with HLX01 (HanliKang(®)), a rituximab biosimilar, in previously untreated patients with diffuse large B-cell lymphoma: 5-year follow-up results of the phase 3 HLX01-NHL03 study

HLX01（韩利康®，一种利妥昔单抗生物类似药）治疗既往未接受治疗的弥漫性大B细胞淋巴瘤患者的长期疗效：3期HLX01-NHL03研究的5年随访结果

Advances of HIF‑1α/glycolysis axis in non‑small cell lung cancer (Review)

非小细胞肺癌中 HIF-1α/糖酵解轴的研究进展（综述）

Iron and copper: critical executioners of ferroptosis, cuproptosis and other forms of cell death

铁和铜：铁死亡、铜死亡和其他形式细胞死亡的关键执行者

Integrative analysis of multi-omics data reveals inhibition of RB1 signaling promotes apatinib resistance of hepatocellular carcinoma

多组学数据整合分析揭示RB1信号抑制促进肝细胞癌对阿帕替尼产生耐药性