日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Identification of A p300-SP1-BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome

鉴定p300-SP1-BRD4转录轴为多囊卵巢综合征中雄激素受体过度激活的关键驱动因素

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202518185
Zhu, Zhengquan; Wang, Yihan; Chen, Haiyun; Yu, Xinye; Wang, Tingyu; Weng, Yajing; Guo, Meihong; Huang, Ying; Tao, Gaojian; Cao, Wangsen; Wang, Yong; Wang, Daojuan
信号转导
BRD4
多囊卵巢综合征
SP1
免疫/内分泌
发表日期：2026
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miR-135a-5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure.

miR-135a-5p 是一个有希望的靶点，可以预防产前地塞米松暴露引起的后代足细胞发育毒性相关的肾小球硬化症。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519743
Zhao Xiaoqi, Chen Haiyun, Zhu Yanan, Xia Zhiping, He Hangyuan, Liu Yutang, Yang Tianshu, Wang Hui, Ao Ying
细胞生物学
发表日期：2026
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Methylation reader MBD2-mediated GPX4 transcriptional repression drives ovarian granulosa cell ferroptosis in PCOS.

甲基化读取蛋白 MBD2 介导的 GPX4 转录抑制驱动多囊卵巢综合征中的卵巢颗粒细胞铁死亡。

期刊:Redox Biology
影响因子:11.9
doi:10.1016/j.redox.2026.104034
Zhu Zhengquan, Wang Yihan, Yu Xinye, Wang Tingyu, Li Yin, Wang Ruizhe, Chen Haiyun, Ruan Binjia, Cao Wangsen, Tao Gaojian, Wang Yong, Wang Daojuan
多囊卵巢综合征
细胞生物学
粒细胞
GPX4
MBD2
铁死亡
发表日期：2026
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Dual asparagine-depriving nanoparticles against solid tumors

双重天冬酰胺剥夺纳米颗粒对抗实体瘤

期刊:Nature Communications
影响因子:14.7
doi:10.1038/s41467-025-60798-y
Yubo Shen # ，Huifang Wang # ，Daoxia Guo ，Jiantao Liu ，Jinli Sun ，Nan Chen ，Haiyun Song ，Xiaoyuan Ji
发表日期：2025
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Thymic Bmi-1 hampers γδT17 generation and its derived RORγt-IL-17A signaling to delay cardiac aging

胸腺Bmi-1抑制γδT17的生成及其衍生的RORγt-IL-17A信号通路，从而延缓心脏衰老

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.2414717122
Wang, Qiuyi; Wang, Yue; Lin, Yujie; Zhou, Jiawen; Mao, Zhiyuan; Gu, Xin; Chen, Haiyun; Li, Jiyu; Chen, Ao; Zhang, Jin'ge; Wang, Rong; Zhao, Yingming; Gu, Mufeng; Li, Qing; Zhang, Yongjie; Jin, Jianliang
IL-17
RORγt
信号转导
IL-17A
衰老
发表日期：2025
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Dexamethasone induces transgenerational inheritance of fetal-derived glomerulosclerosis phenotype in offspring through GR/DNMT3a mediated alterations of the lncRNA-Meg3/Notch signaling pathway.

地塞米松通过 GR/DNMT3a 介导的 lncRNA-Meg3/Notch 信号通路改变，诱导子代发生胎儿来源的肾小球硬化表型的跨代遗传

期刊:Cell Communication and Signaling
影响因子:8.9
doi:10.1186/s12964-025-02346-1
Zhao Xiaoqi, Wang Zhaojun, Xia Zhiping, Chen Haiyun, Zhu Yanan, Wang Songdi, Bao Yan, Liu Yutang, Wang Hui, Ao Ying
信号转导
Notch
发表日期：2025
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Fibroblasts-specific p16(INK4a) exacerbates inflammageing-mediated post-infarction ventricular remodelling through interacting with STAT3 to regulate NLRP3 transcription

成纤维细胞特异性p16(INK4a)通过与STAT3相互作用调节NLRP3转录，加剧炎症衰老介导的梗死后心室重塑。

期刊:Clinical and Translational Medicine
影响因子:6.8
doi:10.1002/ctm2.70344
Gu, Xin; Du, Yingqiang; Zhang, Jin'ge; Li, Jiyu; Chen, Haiyun; Lin, Yujie; Wang, Yue; Zhang, Chunli; Lin, Shiyu; Hao, Nannan; Peng, Chengyi; Ge, Jiacheng; Liu, Jin; Liang, Yan; Zhang, Yongjie; Wang, Xiaoyan; Wang, Fang; Jin, Jianliang
成纤维细胞
炎症
炎症/感染
JAK/STAT
STAT3
LRP3
衰老
NLRP3
细胞生物学
发表日期：2025
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The communication role of extracellular vesicles in the osteoarthritis microenvironment

细胞外囊泡在骨关节炎微环境中的通讯作用

期刊:Frontiers in Immunology
影响因子:5.9
doi:10.3389/fimmu.2025.1549833
Chen, Pu; Zeng, Lingfeng; Wang, Ting; He, Jianbo; Xiong, Shuai; Chen, Gang; Wang, Qingfu; Chen, Haiyun; Xie, Jiewei
囊泡
关节炎
细胞生物学
发表日期：2025
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Integrated morphological, physiological, and transcriptomic analyses uncover the mechanisms of waterlogging tolerance in Sorghum bicolor (L.)

综合形态学、生理学和转录组学分析揭示了高粱（Sorghum bicolor (L.)）耐涝机制

期刊:Frontiers in Plant Science
影响因子:4.8
doi:10.3389/fpls.2025.1706603
Zhang, Ruidong; Chen, Haiyun; Li, Xiang; Wang, Minli; Luo, Yu; Jiao, Wenda; Chang, Jiarong; Cao, Xiong; Feng, Jun
发表日期：2025
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Loss of vitamin D receptor induces premature ovarian insufficiency through compromising the 7-dehydrocholesterol-dependent anti-aging effects.

维生素 D 受体的丧失会损害 7-脱氢胆固醇依赖的抗衰老作用，从而导致卵巢早衰

期刊:Frontiers in Cell and Developmental Biology
影响因子:4.3
doi:10.3389/fcell.2025.1545167
Chen Haiyun, Wang Qiuyi, Zhang Yi, Shangguan Luxi, Zhu Zhengquan, Zhang Huan, Zou Xiang, Geng Qinghe, Wen Yanting, Wang Daojuan, Wang Yong
其它
细胞衰老
发表日期：2025
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