日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Targeting ENO1 reprograms macrophage polarization to trigger antitumor immunity and improves the therapeutic effect of radiotherapy.

靶向 ENO1 可重编程巨噬细胞极化，从而触发抗肿瘤免疫，并提高放射疗法的治疗效果。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-026-08416-7
Lin Yu-Sen, Chang Hsin-Yu, Hong Wei-Ze, Chen Jhen-Yu, Huang Wei-Ching, Yuan Ta-Tung, Ke Tao-Wei, Tsai Yuan-Yao, Chen Te-Hong, Liang Ji-An, Chao Jui-I, Chao K S Clifford, Huang Kevin Chih-Yang
细胞生物学
巨噬细胞
肿瘤免疫
巨噬细胞
发表日期：2026
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Loss of MicroRNA-29b promotes DNMT3b-mediated STING downregulation to attenuate radiotherapy-induced antitumor immunity in KRAS-mutated colorectal cancer.

MicroRNA-29b 的缺失促进 DNMT3b 介导的 STING 下调，从而减弱 KRAS 突变型结直肠癌中放射治疗诱导的抗肿瘤免疫。

期刊:npj Precision Oncology
影响因子:8
doi:10.1038/s41698-026-01290-8
Chang Hsin-Yu, Chen Jhen-Yu, Ke Tao-Wei, Jiang Yi-Wen, Hong Wei-Ze, Tsai Yuan-Yao, Chiang Shu-Fen, Lin Yu-Sen, Huang Chi-Hsien, Chen Te-Hong, Chao K S Clifford, Huang Kevin Chih-Yang
肿瘤
肠癌
肿瘤免疫
STING
RAS
免疫/内分泌
发表日期：2026
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Heterologous prime-boost immunization of AAV-based neoantigen cancer vaccine induces anti-tumor immunity to inhibit tumor growth and relapse.

基于 AAV 的新抗原癌症疫苗的异源初免-加强免疫可诱导抗肿瘤免疫，从而抑制肿瘤生长和复发。

期刊:Cancer Immunology Immunotherapy
影响因子:5.1
doi:10.1007/s00262-026-04336-9
Huang Chi-Hsien, Chen Jhen-Yu, Chang Hsin-Yu, Hong Wei-Ze, Jiang Yi-Wen, Lee Chien-Yueh, Wu Chia-Hsin, Lin Yu-Sen, Tsai Yuan-Yao, Kao Wei-Ling, Chao K S Clifford, Huang Kevin Chih-Yang
免疫/内分泌
肿瘤免疫
发表日期：2026
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CHK1 inhibition increases the therapeutic response to radiotherapy via antitumor immunity in ARID1A-deficient colorectal cancer.

CHK1 抑制通过 ARID1A 缺陷型结直肠癌的抗肿瘤免疫增强放射治疗的疗效

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07912-6
Chen Jhen-Yu, Ke Tao-Wei, Chiang Shu-Fen, Hong Wei-Ze, Chang Hsin-Yu, Liang Ji-An, Tsai Yuan-Yao, Huang Chi-Hsien, Chen William Tzu-Liang, Chao K S Clifford, Huang Kevin Chih-Yang
肿瘤
肿瘤免疫
发表日期：2025
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Nuclear IKKα mediates microRNA-7/-103/107/21 inductions to downregulate maspin expression in response to HBx overexpression

核 IKKα 介导 microRNA-7/-103/107/21 诱导，从而下调 HBx 过表达引起的 maspin 表达

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.10462
Wen-Shu Chen, Liang-Chih Liu, Chia-Jui Yen, Yun-Ju Chen, Jhen-Yu Chen, Chien-Yi Ho, Shu-Hui Liu, Ching-Chow Chen, Wei-Chien Huang2
发表日期：2016
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miRNA-7/21/107 contribute to HBx-induced hepatocellular carcinoma progression through suppression of maspin

miRNA-7/21/107 通过抑制 maspin 促进 HBx 诱导的肝细胞癌进展。

期刊:Oncotarget
影响因子:
doi:10.18632/oncotarget.4504
Chen, Wen-Shu; Yen, Chia-Jui; Chen, Yun-Ju; Chen, Jhen-Yu; Wang, Li-Yun; Chiu, Shu-Jun; Shih, Wen-Ling; Ho, Chien-Yi; Wei, Tzu-Tang; Pan, Hsiao-Lin; Chien, Pei-Hsuan; Hung, Mien-Chie; Chen, Ching-Chow; Huang, Wei-Chien
miRNA
细胞生物学
肿瘤
肿瘤免疫
发表日期：2015
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