Chen Linyun相关文献与解析，生知库 | 链接生命科学的每一步

Identification of chalcone analogues as anti-inflammatory agents through the regulation of NF-ÎºB and JNK activation.

通过调节 NF-κB 和 JNK 激活，鉴定查尔酮类似物作为抗炎剂

Zhang Die, Wang Wenping, Ou Huiping, Ning Jinhua, Zhou Yingxun, Ke Jin, Hou Anguo, Chen Linyun, Li Peng, Ma Yunshu, Jin Wen Bin

炎症/感染

Targeting Grancalcin Accelerates Wound Healing by Improving Angiogenesis in Diabetes

靶向 Grancalcin 可通过改善糖尿病中的血管生成来加速伤口愈合

期刊:Advanced Science

影响因子:

doi:10.1002/advs.202305856

Peng Xiang, Meng Jiang, Xin Chen, Linyun Chen, Yalun Cheng, Xianghang Luo, Haiyan Zhou, Yongjun Zheng

Synthesis and In Vivo Antiarrhythmic Activity Evaluation of Novel Scutellarein Analogues as Voltage-Gated Nav1.5 and Cav1.2 Channels Blockers

新型黄芩素类似物作为电压门控 Nav1.5 和 Cav1.2 通道阻滞剂的合成及体内抗心律失常活性评价

期刊:Molecules

影响因子:4.6

doi:10.3390/molecules28217417

Yang, Wei; Wang, Wenping; Cai, Song; Li, Peng; Zhang, Die; Ning, Jinhua; Ke, Jin; Hou, Anguo; Chen, Linyun; Ma, Yunshu; Jin, Wenbin

发表日期：2023

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Identification of isothiazolones analogues as potent bactericidal agents against antibiotic resistant CRE and MRSA strains

鉴定异噻唑啉类似物为对抗耐抗生素CRE和MRSA菌株的强效杀菌剂

期刊:BMC Chemistry

影响因子:4.6

doi:10.1186/s13065-023-01100-3

Jin, Wenbin; Xu, Chen; Dong, Ning; Chen, Kaichao; Zhang, Die; Ning, Jinhua; Li, Yunbing; Zhang, Guangfen; Ke, Jin; Hou, Anguo; Chen, Linyun; Chen, Sheng; Chan, Kin-Fai

发表日期：2023

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Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

成年小鼠肝脏特异性敲除Nrf1基因会导致非酒精性脂肪性肝炎和肝脏肿瘤。

期刊:Proceedings of the National Academy of Sciences of the United States of America

影响因子:9.1

doi:10.1073/pnas.0500660102

Xu, Zhenrong; Chen, Linyun; Leung, Laura; Yen, T S Benedict; Lee, Candy; Chan, Jefferson Y

Nrf1 is critical for redox balance and survival of liver cells during development

Nrf1在发育过程中对肝细胞的氧化还原平衡和存活至关重要。

期刊:Molecular and Cellular Biology

影响因子:2.7

doi:10.1128/MCB.23.13.4673-4686.2003

Chen, Linyun; Kwong, Mandy; Lu, Ronghua; Ginzinger, David; Lee, Candy; Leung, Laura; Chan, Jefferson Y

Nutrient-driven histone acetylation underlies energy storage and mobilization.

营养物质驱动的组蛋白乙酰化是能量储存和动员的基础。

Identification of chalcone analogues as anti-inflammatory agents through the regulation of NF-ÎºB and JNK activation.

通过调节 NF-κB 和 JNK 激活，鉴定查尔酮类似物作为抗炎剂

Targeting Grancalcin Accelerates Wound Healing by Improving Angiogenesis in Diabetes

靶向 Grancalcin 可通过改善糖尿病中的血管生成来加速伤口愈合

Synthesis and In Vivo Antiarrhythmic Activity Evaluation of Novel Scutellarein Analogues as Voltage-Gated Nav1.5 and Cav1.2 Channels Blockers

新型黄芩素类似物作为电压门控 Nav1.5 和 Cav1.2 通道阻滞剂的合成及体内抗心律失常活性评价

Identification of isothiazolones analogues as potent bactericidal agents against antibiotic resistant CRE and MRSA strains

鉴定异噻唑啉类似物为对抗耐抗生素CRE和MRSA菌株的强效杀菌剂

Liver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasia

成年小鼠肝脏特异性敲除Nrf1基因会导致非酒精性脂肪性肝炎和肝脏肿瘤。

Nrf1 is critical for redox balance and survival of liver cells during development

Nrf1在发育过程中对肝细胞的氧化还原平衡和存活至关重要。