日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Chiral metal nanozyme-enabled SOD2 activation and siRNA delivery cooperatively mitigating chronic heart failure.

手性金属纳米酶激活 SOD2 和 siRNA 递送，协同缓解慢性心力衰竭。

期刊:Bioactive Materials
影响因子:20.3
doi:10.1016/j.bioactmat.2025.11.049
Wang Zekun, Zhang Ruofei, Hu Yanyu, Song Qile, Fu Xiaoyan, Wang Yifan, Chen Mei, Fan Kelong, Fan Cundong, Sun Dongdong
心力衰竭
心血管
SOD2
发表日期：2026
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Reprogramming the Tumor Mechanical Microenvironment with Lactate Inhibition and Stimulator of Interferon Genes Activation to Potentiate Systematic Radio-Immunotherapy

利用乳酸抑制和干扰素基因激活刺激因子重编程肿瘤机械微环境，以增强全身放射免疫疗法的效果

期刊:ACS Nano
影响因子:16
doi:10.1021/acsnano.5c16809
Mao, Qiulian; Cai, Hui; Chen, Mei; Xiao, Ang; Jiao, Haorong; Jia, Fang; Ma, Jicun; Fan, Jiada; Liu, Jing; Zhang, Kangbo; Wu, Xinyue; Liu, Yilin; Cui, Jiabin; Chen, Wei-Hai
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Template-free synthesis of colloidal quantum dot assemblies with molecule-like architectures

无模板合成具有分子状结构的胶体量子点组装体

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-70555-4
Fan, Jiada; Ying, Zhuang; Ma, Jicun; Xu, Jialiang; Cai, Hui; Liu, Jing; Wu, Xinyue; Yang, Chenhao; Jiao, Haorong; Mao, Qiulian; Chen, Mei; Xiao, Liantuan; Peng, Yonggang; Zhang, Guofeng; Cui, Jiabin; Gao, Mingyuan
发表日期：2026
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CDK2 inhibitor BLU-222 synergizes with CDK4/6 inhibitors in drug resistant breast cancers through p21/p27 induction

CDK2抑制剂BLU-222通过诱导p21/p27与CDK4/6抑制剂协同作用，治疗耐药性乳腺癌。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-67865-4
Luo, Linjie; Wang, Yan; Bui, Tuyen; Jiang, Xiaoting; Chen, Mei-Kuang; Rao, Xiayu; Mohammadhosseinpour, Sepideh; Li, Mi; Kim, Serena; Kim, Rachel Y; Kamaliasl, Saba; Ulizio, Carmen W; Tsavachidis, Spyros; Navarro-Yepes, Juliana; Kettner, Nicole M; Wingate, Hannah; Meric-Bernstam, Funda; Hunt, Kelly K; Wang, Jing; Faia, Kerrie; Keyomarsi, Khandan
CDK4
肿瘤
肿瘤免疫
治疗耐药
乳腺癌
CDK2
发表日期：2026
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Non-Targeting shRNA-Encoded Plasmid DNA Enhances Protective Immunity Through RIDD-RIG-I Signaling Pathway in the Zika Virus Animal Model.

非靶向 shRNA 编码的质粒 DNA 通过 RIDD-RIG-I 信号通路增强寨卡病毒动物模型的保护性免疫。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202517420
Huang Min-Syuan, Liao Hung-Chun, Peng Po, Wu Wan-Ling, Chai Kit Man, Chen Mei-Yu, Yu Guann-Yi, Chuang Tsung-Hsien, Chen Hsin-Wei, Chang Chuang-Rung, Liu Shih-Jen
信号转导
Rig-I
发表日期：2026
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CD3ɛ Nanobody-Engineered Extracellular Vesicles Driving In Vivo Generation of TCE-secreting CAR-Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity.

CD3É› 纳米抗体工程化细胞外囊泡驱动体内生成分泌 TCE 的 CAR-T 细胞，用于实体瘤治疗，具有记忆反应和最小免疫原性。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519440
Huang Shi-Wei, Lin Yu-Chuan, Pan Chih-Ming, Chen Yeh, Shie Ming-You, Chen Cheng-Yu, Kan Kai-Wen, Chen Yi-Wen, Liu Ming-Chao, Wu Chung-Chun, Chiang Yu-Ting, Ho Huai-Ping, Lin Chen-Yu, Lin Pei-Ying, Huang Yu-Han, Rusli Steffany, Mao Wan-Yu, Huang Pei-Wen, Wang Sin-Ting, Tsai Wan-Chen, Chiu Ya-Hsu, Lin Ting-Hsun, Chiang Wan-Ling, Chang Che-Kai, Lai Zi-Lun, Chen Mei-Chih, Chiu Shao-Chih, Cho Der-Yang
细胞生物学
CD3
囊泡
发表日期：2026
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Lipid nanoparticle-formulated DNA acts as a potent immune modulator for cancer immunotherapy through interferon signaling pathways

脂质纳米颗粒包裹的DNA通过干扰素信号通路发挥强效免疫调节剂的作用，用于癌症免疫治疗。

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.121364
Chiang, Chen-Yi; Hsieh, Ming-Shu; Chen, Mei-Yu; Tsai, Yu-Wen; Lin, Chang-Ling; Hsu, Chia-Wei; Yu, Guann-Yi; Huang, Ming-Hsi; Liu, Shih-Jen; Chen, Hsin-Wei
信号转导
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Triple-Targeted DNA Nanozyme Executes Disulfidptosis for Glioma Elimination

三靶点DNA纳米酶通过二硫键诱导细胞凋亡清除胶质瘤

期刊:Theranostics
影响因子:13.3
doi:10.7150/thno.133314
Wu, Tiantian; Li, Le; Zhang, Shun; Zhang, Guannan; Li, Chen; Mei, Jiaming; Chen, Xiaoyuan; Cheng, Junjie
胶质瘤
凋亡
表观遗传
细胞生物学
发表日期：2026
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A rural-to-center artificial intelligence model for diagnosing Helicobacter pylori infection and premalignant gastric conditions using endoscopy images captured in routine practice

一种利用常规诊疗中采集的内镜图像，从农村到中心的人工智能模型，用于诊断幽门螺杆菌感染和胃癌前病变。

期刊:Endoscopy
影响因子:12.8
doi:10.1055/a-2721-6552
Chiang, Tsung-Hsien; Hsu, Yen-Ning; Chen, Min-Han; Chen, Yi-Ru; Cheng, Hsiu-Chi; Chen, Mei-Jin; Lee, Fu-Jen; Chang, Chi-Yang; Chang, Chun-Chao; Bair, Ming-Jong; Liou, Jyh-Ming; Chen, Chiuan-Jung; Chen, Yen-Chung; Chiang, Hung; Shun, Chia-Tung; Liu, Jui-Hsuan; Chiu, Han-Mo; Wu, Ming-Shiang; Yu, Jiun-Yu; Guo, Ruey-Shan; Lin, Jaw-Town; Lee, Yi-Chia; Chen, Chu-Song
胃癌
肿瘤
肿瘤免疫
炎症/感染
发表日期：2026
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Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury

构建靶向整合素αvβ8的细胞外囊泡，以递送BDNF mRNA促进脊髓损伤后的运动功能恢复

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04222-7
Shie, Ming-You; Chiu, Cheng-Di; Chen, Yeh; Lin, Yen-Hong; Yu, Min-Hua; Chiu, You-Pen; Chiu, Po-Fan; Chen, Cheng-Yu; Chen, Yi-Wen; Chen, Mei-Chih; Cho, Der-Yang
神经科学
脊髓损伤
BDNF
囊泡
细胞生物学
发表日期：2026
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