日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CD3ɛ Nanobody-Engineered Extracellular Vesicles Driving In Vivo Generation of TCE-secreting CAR-Ts for Solid Tumor Therapy With Memory Response and Minimal Immunogenicity.

CD3É› 纳米抗体工程化细胞外囊泡驱动体内生成分泌 TCE 的 CAR-T 细胞，用于实体瘤治疗，具有记忆反应和最小免疫原性。

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519440
Huang Shi-Wei, Lin Yu-Chuan, Pan Chih-Ming, Chen Yeh, Shie Ming-You, Chen Cheng-Yu, Kan Kai-Wen, Chen Yi-Wen, Liu Ming-Chao, Wu Chung-Chun, Chiang Yu-Ting, Ho Huai-Ping, Lin Chen-Yu, Lin Pei-Ying, Huang Yu-Han, Rusli Steffany, Mao Wan-Yu, Huang Pei-Wen, Wang Sin-Ting, Tsai Wan-Chen, Chiu Ya-Hsu, Lin Ting-Hsun, Chiang Wan-Ling, Chang Che-Kai, Lai Zi-Lun, Chen Mei-Chih, Chiu Shao-Chih, Cho Der-Yang
细胞生物学
CD3
囊泡
发表日期：2026
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Engineering integrin αvβ8-targeted extracellular vesicles to deliver BDNF mRNA for motor recovery in spinal cord injury

构建靶向整合素αvβ8的细胞外囊泡，以递送BDNF mRNA促进脊髓损伤后的运动功能恢复

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-026-04222-7
Shie, Ming-You; Chiu, Cheng-Di; Chen, Yeh; Lin, Yen-Hong; Yu, Min-Hua; Chiu, You-Pen; Chiu, Po-Fan; Chen, Cheng-Yu; Chen, Yi-Wen; Chen, Mei-Chih; Cho, Der-Yang
神经科学
脊髓损伤
BDNF
囊泡
细胞生物学
发表日期：2026
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Engineering HLA-G-targeted extracellular vesicles nanoplatform for enhanced cancer therapy through precise cancer drug delivery.

构建靶向 HLA-G 的细胞外囊泡纳米平台，通过精准的癌症药物递送增强癌症治疗效果。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-66451-y
Shie Ming-You, Huang Shi-Wei, Chen Yeh, Chen Mei-Chih, Pan Chih-Ming, Chen Cheng-Yu, Lin Yen-Hong, Yu Min-Hua, Kan Kai-Wen, Chiu Shao-Chih, Ho Hui-Chun, Chen Yi-Wen, Cho Der-Yang
细胞生物学
囊泡
发表日期：2025
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Engineered extracellular vesicles-mediated curcumin delivery in brain microenvironment modulating lysosomes, mitochondria, and microglia reprogram for parkinson's disease therapy

利用工程化细胞外囊泡介导的姜黄素递送系统，在大脑微环境中调节溶酶体、线粒体和小胶质细胞的重编程，从而治疗帕金森病。

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-025-03911-z
Shie, Ming-You; Chen, Mei-Chih; Chen, Yeh; Huang, Shi-Wei; Lin, Yen-Hong; Yu, Min-Hua; Pan, Chih-Ming; Chen, Cheng-Yu; Chen, Yi-Wen; Hsieh, Ching-Liang; Chiu, Shao-Chih; Kao, Shung-Te; Lin, Jaung-Geng; Cho, Der-Yang
胶质细胞
帕金森
神经科学
线粒体
囊泡
细胞生物学
发表日期：2025
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CDK5 targets p21(CIP1) to regulate thyroid cancer cell proliferation and malignancy in patients.

CDK5 靶向 p21(CIP1) 以调节甲状腺癌细胞增殖和患者恶性程度

期刊:Molecular Medicine Reports
影响因子:3.5
doi:10.3892/mmr.2025.13547
Tung Min-Che, Oner Muhammet, Soong Shiuan-Woei, Cheng Pang-Ting, Li Yu-Hsuan, Chen Mei-Chih, Chou Chen-Kai, Kang Hong-Yo, Lin Frank Cheau-Feng, Tsai Stella Chin-Shaw, Lin Ho
细胞生物学
发表日期：2025
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Targeting Dual Immune Checkpoints PD-L1 and HLA-G by Trispecific T Cell Engager for Treating Heterogeneous Lung Cancer

利用三特异性T细胞衔接器靶向双重免疫检查点PD-L1和HLA-G治疗异质性肺癌

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202309697
Lin, Yu-Chuan; Chen, Mei-Chih; Huang, Shi-Wei; Chen, Yeh; Ho, Jennifer Hui-Chun; Lin, Fang-Yu; Tan, Xiao-Tong; Chiang, Hung-Che; Huang, Chiu-Ching; Tu, Chih-Yen; Cho, Der-Yang; Chiu, Shao-Chih
Checkpoint
肺癌
肿瘤
T细胞
肿瘤免疫
PD-L1
T细胞
细胞生物学
免疫/内分泌
发表日期：2024
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Future Aspects of CDK5 in Prostate Cancer: From Pathogenesis to Therapeutic Implications

CDK5在前列腺癌中的未来展望：从发病机制到治疗意义

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms20163881
Oner, Muhammet; Lin, Eugene; Chen, Mei-Chih; Hsu, Fu-Ning; Shazzad Hossain Prince, G M; Chiu, Kun-Yuan; Teng, Chieh-Lin Jerry; Yang, Tsung-Ying; Wang, Hsin-Yi; Yue, Chia-Herng; Yu, Ching-Han; Lai, Chih-Ho; Hsieh, Jer-Tsong; Lin, Ho
肿瘤
前列腺癌
肿瘤免疫
CDK5
发表日期：2019
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Interaction between cytochrome P450 2A6 and Catechol-O-Methyltransferase genes and their association with smoking risk in young men

细胞色素P450 2A6和儿茶酚-O-甲基转移酶基因之间的相互作用及其与年轻男性吸烟风险的关系

期刊:Behavioral and Brain Functions
影响因子:3.3
doi:10.1186/s12993-017-0127-2
Ou, Wei-Chih; Huang, Yi-Chin; Huang, Chih-Ling; Lin, Min-Hsuan; Chen, Yi-Chun; Chen, Yi-Ju; Liu, Chen-Nu; Chen, Mei-Chih; Huang, Ching-Shan; Chen, Pei-Lain
细胞生物学
发表日期：2017
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Reasoning the causality of city sprawl, traffic congestion, and green land disappearance in Taiwan using the CLD model

利用CLD模型分析台湾城市扩张、交通拥堵和绿地消失的因果关系

期刊:International Journal of Environmental Research and Public Health
影响因子:
doi:10.3390/ijerph111111464
Chen, Mei-Chih; Chang, Kaowen
发表日期：2014
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Regulation of androgen receptor and prostate cancer growth by cyclin-dependent kinase 5

细胞周期蛋白依赖性激酶5对雄激素受体和前列腺癌生长的调控

期刊:Journal of Biological Chemistry
影响因子:3.9
doi:10.1074/jbc.M111.252080
Hsu, Fu-Ning; Chen, Mei-Chih; Chiang, Ming-Ching; Lin, Eugene; Lee, Yueh-Tsung; Huang, Pao-Hsuan; Lee, Guan-Shun; Lin, Ho
肿瘤
肿瘤免疫
信号转导
细胞生物学
前列腺癌
免疫/内分泌
发表日期：2011
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