日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Single dose thermoresponsive dexamethasone prodrug completely mitigates joint pain for 15 weeks in a murine model of osteoarthritis

单剂量热敏性地塞米松前药可在小鼠骨关节炎模型中完全缓解关节疼痛，疗效持续15周。

期刊:Nanomedicine-Nanotechnology Biology and Medicine
影响因子:4.6
doi:10.1016/j.nano.2024.102735
Chen, Ningrong; Wei, Xin; Zhao, Gang; Jia, Zhenshan; Fu, Xin; Jiang, Haochen; Xu, Xiaoke; Zhao, Zhifeng; Singh, Purva; Lessard, Samantha; Otero, Miguel; Goldring, Mary B; Goldring, Steven R; Wang, Dong
关节炎
发表日期：2024
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Identification of formulation parameters that affect the analgesic efficacy of ProGel-Dex - A thermoresponsive polymeric dexamethasone prodrug for chronic arthritis pain relief

确定影响ProGel-Dex镇痛效果的制剂参数——ProGel-Dex是一种用于缓解慢性关节炎疼痛的热响应性聚合物地塞米松前药

期刊:Nanomedicine-Nanotechnology Biology and Medicine
影响因子:4.6
doi:10.1016/j.nano.2024.102782
Wei, Xin; Zhao, Gang; Chen, Ningrong; Xu, Xiaoke; Jiang, Haochen; Tran, Daniel; Glissmeyer, Evan; Goldring, Mary B; Goldring, Steven R; Wang, Dong
关节炎
发表日期：2024
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Thermoresponsive Polymeric Hydromorphone Prodrug Provides Sustained Local Analgesia without Apparent Adverse Effects

热响应性聚合物氢吗啡酮前药可提供持续的局部镇痛作用，且无明显不良反应。

期刊:Molecular Pharmaceutics
影响因子:4.5
doi:10.1021/acs.molpharmaceut.3c01133
Jia, Zhenshan; Wei, Xin; Chen, Ningrong; Xu, Xiaoke; Zhao, Gang; Fu, Xin; Wang, Hanjun; Goldring, Mary B; Goldring, Steven R; Wang, Dong
发表日期：2024
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Polymeric dexamethasone prodrugs attenuate lupus nephritis in MRL/lpr mice with reduced glucocorticoid toxicity

聚合物地塞米松前药可减轻MRL/lpr小鼠的狼疮性肾炎，并降低糖皮质激素毒性。

期刊:Nanomedicine-Nanotechnology Biology and Medicine
影响因子:4.6
doi:10.1016/j.nano.2022.102579
Zhao, Zhifeng; Jiang, Haochen; Xu, Xiaoke; Jia, Zhenshan; Ren, Rongguo; Foster, Kirk W; Wei, Xin; Chen, Ningrong; Goldring, Steven R; Crow, Mary K; Wang, Dong
毒理研究
肾炎
免疫/内分泌
发表日期：2022
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Preclinical Dose-Escalation Study of ZSJ-0228, a Polymeric Dexamethasone Prodrug, in the Treatment of Murine Lupus Nephritis

ZSJ-0228（一种聚合物地塞米松前药）治疗小鼠狼疮性肾炎的临床前剂量递增研究

期刊:Molecular Pharmaceutics
影响因子:4.5
doi:10.1021/acs.molpharmaceut.1c00567
Zhao, Zhifeng; Xu, Xiaoke; Jiang, Haochen; Foster, Kirk W; Jia, Zhenshan; Wei, Xin; Chen, Ningrong; Goldring, Steven R; Crow, Mary K; Wang, Dong
肾炎
发表日期：2021
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GSK3 inhibitor-loaded osteotropic Pluronic hydrogel effectively mitigates periodontal tissue damage associated with experimental periodontitis.

载有 GSK3 抑制剂的骨向性 Pluronic 水凝胶可有效减轻实验性牙周炎引起的牙周组织损伤

期刊:Biomaterials
影响因子:12.9
doi:10.1016/j.biomaterials.2020.120293
Almoshari Yosif, Ren Rongguo, Zhang Haipeng, Jia Zhenshan, Wei Xin, Chen Ningrong, Li Guojuan, Ryu Sangjin, Lele Subodh M, Reinhardt Richard A, Wang Dong
免疫/内分泌
发表日期：2020
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Head-to-head comparative pharmacokinetic and biodistribution (PK/BD) study of two dexamethasone prodrug nanomedicines on lupus-prone NZB/WF1 mice

在易患狼疮的NZB/WF1小鼠中，对两种地塞米松前药纳米制剂进行了头对头比较药代动力学和生物分布（PK/BD）研究。

期刊:Nanomedicine-Nanotechnology Biology and Medicine
影响因子:4.6
doi:10.1016/j.nano.2020.102266
Wei, Xin; Zhao, Gang; Wang, Xiaobei; Gautam, Nagsen; Jia, Zhenshan; Zhao, Zhifeng; Kong, Dexuan; Zhang, Fan; Kumar, Sushil; Sun, Yuanyuan; Chen, Ningrong; Wang, Xiaoyan; Yang, Libin; Ren, Rongguo; Thiele, Geoffrey M; Bronich, Tatiana K; O'Dell, James R; Alnouti, Yazen; Wang, Dong
发表日期：2020
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