Microglial PGC-1α alleviates synaptic damage and cognitive impairments following anesthesia and surgery by suppressing excessive synaptic pruning in aged mice.
小胶质细胞 PGC-1α 通过抑制老年小鼠过度突触修剪来减轻麻醉和手术后的突触损伤和认知障碍。
期刊:International Journal of Biological Sciences
影响因子:10
doi:10.7150/ijbs.121472
Wu Xuyang, Xu Maokai, Huang Yongxin, Chen Pinzhong, Wu Liang, Chen Andi, Wei Jianjie, Chen Yingjie, Lin Yongbao, Lin Yingceng, Lin Zhe, Lin Ying, Xue Fushan, Chen Xiaohui, Zheng Xiaochun
