ALT neuroblastoma chemoresistance due to telomere dysfunction-induced ATM activation is reversible with ATM inhibitor AZD0156
ALT神经母细胞瘤因端粒功能障碍诱导的ATM激活而产生的化疗耐药性可通过ATM抑制剂AZD0156逆转。
期刊:Science Translational Medicine
影响因子:14.6
doi:10.1126/scitranslmed.abd5750
Koneru, Balakrishna; Farooqi, Ahsan; Nguyen, Thinh H; Chen, Wan Hsi; Hindle, Ashly; Eslinger, Cody; Makena, Monish Ram; Burrow, Trevor A; Wilson, Joanne; Smith, Aaron; Pilla Reddy, Venkatesh; Cadogan, Elaine; Durant, Stephen T; Reynolds, C Patrick
