日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells

作者更正:选择性 HDAC6 抑制剂通过降低巨噬细胞的抗炎表型和下调肿瘤细胞中的免疫抑制蛋白,从而改善抗 PD-1 免疫检查点阻断疗法的疗效。

Knox, Tessa; Sahakian, Eva; Banik, Debarati; Hadley, Melissa; Palmer, Erica; Noonepalle, Satish; Kim, Jennifer; Powers, John; Gracia-Hernandez, Maria; Oliveira, Vasco; Cheng, Fengdong; Chen, Jie; Barinka, Cyril; Pinilla-Ibarz, Javier; Lee, Norman H; Kozikowski, Alan; Villagra, Alejandro

Stat3 inhibition augments the immunogenicity of B-cell lymphoma cells, leading to effective antitumor immunity.

Stat3 抑制可增强 B 细胞淋巴瘤细胞的免疫原性,从而产生有效的抗肿瘤免疫

Cheng Fengdong, Wang Hongwei, Horna Pedro, Wang Zi, Shah Bijal, Sahakian Eva, Woan Karrune V, Villagra Alejandro, Pinilla-Ibarz Javier, Sebti Said, Smith Mitchell, Tao Jianguo, Sotomayor Eduardo M

Enhanced CD8 T cell cross-presentation by macrophages with targeted disruption of STAT3

靶向破坏 STAT3 可增强巨噬细胞对 CD8 T 细胞的交叉呈递

Brayer, Jason; Cheng, Fengdong; Wang, Hongwei; Horna, Pedro; Vicente-Suarez, Ildefonso; Pinilla-Ibarz, Javier; Sotomayor, Eduardo M

TLR5 ligation by flagellin converts tolerogenic dendritic cells into activating antigen-presenting cells that preferentially induce T-helper 1 responses

鞭毛蛋白与TLR5结合可将耐受性树突状细胞转化为激活性抗原呈递细胞,这些细胞优先诱导T辅助细胞1型(Th1)反应。

Vicente-Suarez, Ildelfonso; Brayer, Jason; Villagra, Alejandro; Cheng, Fengdong; Sotomayor, Eduardo M