日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Novel small-molecule inhibitors of the protein kinase DYRK: Potential therapeutic candidates in cancer

新型小分子蛋白激酶DYRK抑制剂：癌症治疗的潜在候选药物

期刊:
影响因子:
doi:10.1101/2025.11.05.686653
Venkataramani, Prabhadevi; Elkayam, Elad; Garg, Ankur; Cheng, Kai Fan; Altiti, Ahmad; He, Mingzhu; Thakur, Khushabu; Michalopoulou, Evdokia; Gonzalez, Camila; Felice, Christy; Van-Aelst, Linda; Pappin, Darryl; Joshua-Tor, Leemor; Al-Abed, Yousef; Tonks, Nicholas K
信号转导
肿瘤
DYR
肿瘤免疫
发表日期：2025
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Atom-level backbone engineering preserves peptide function while enhancing stability

原子级骨架工程在保持肽功能的同时增强了其稳定性。

期刊:
影响因子:
doi:10.1101/2025.10.06.678421
He, Mingzhu; Cheng, Kai Fan; Vu, Anh; Torres, Marcelo D T; Zanos, Stavros; Mughrabi, Ibrahim T; de la Fuente-Nunez, Cesar; Al-Abed, Yousef
发表日期：2025
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Protease-Resistant Azapeptide GLP-1 Analogue Improves Metabolic Control in Diet-Induced Obesity

抗蛋白酶的氮杂肽GLP-1类似物可改善饮食诱导肥胖的代谢控制

期刊:
影响因子:
doi:10.1101/2025.05.09.653092
He, Mingzhu; Cheng, Kai Fan; VanPatten, Sonya; Torres, Marcelo D T; Jabari, Bayan Al; Mughrabi, Ibrahim T; Ballarín-González, Borja; Son, Myoungsun; de la Fuente-Nunez, Cesar; Al-Abed, Yousef
肥胖
GLP-1
代谢
发表日期：2025
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Thiocarbazate building blocks enable the construction of azapeptides for rapid development of therapeutic candidates

硫代氨基甲酸酯结构单元可用于构建氮杂肽，从而快速开发治疗候选药物。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-34712-9
Altiti, Ahmad; He, Mingzhu; VanPatten, Sonya; Cheng, Kai Fan; Ahmed, Umair; Chiu, Pui Yan; Mughrabi, Ibrahim T; Jabari, Bayan Al; Burch, Ronald M; Manogue, Kirk R; Tracey, Kevin J; Diamond, Betty; Metz, Christine N; Yang, Huan; Hudson, LaQueta K; Zanos, Stavros; Son, Myoungsun; Sherry, Barbara; Coleman, Thomas R; Al-Abed, Yousef
发表日期：2022
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Endogenous retroviruses are associated with hippocampus-based memory impairment

内源性逆转录病毒与海马体相关的记忆障碍有关。

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1822164116
Sankowski, Roman; Strohl, Joshua J; Huerta, Tomás S; Nasiri, Elham; Mazzarello, Andrea N; D'Abramo, Cristina; Cheng, Kai Fan; Staszewski, Ori; Prinz, Marco; Huerta, Patricio T; Al-Abed, Yousef
微生物学
发表日期：2019
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β-Hydroxy-tetrahydroquinolines from Quinolines Using Chloroborane: Synthesis of the Peptidomimetic FISLE-412

利用氯硼烷由喹啉合成β-羟基四氢喹啉：肽模拟物FISLE-412的合成

期刊:Chemistry-A European Journal
影响因子:3.7
doi:10.1002/chem.201701944
Altiti, Ahmad S; Cheng, Kai Fan; He, Mingzhu; Al-Abed, Yousef
红斑狼疮
发表日期：2017
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Xanomeline suppresses excessive pro-inflammatory cytokine responses through neural signal-mediated pathways and improves survival in lethal inflammation.

Xanomeline 通过神经信号介导的途径抑制过度的促炎细胞因子反应，提高致命性炎症中的生存率

期刊:Brain Behavior and Immunity
影响因子:7.6
doi:10.1016/j.bbi.2014.07.010
Rosas-Ballina Mauricio, Valdés-Ferrer Sergio I, Dancho Meghan E, Ochani Mahendar, Katz David, Cheng Kai Fan, Olofsson Peder S, Chavan Sangeeta S, Al-Abed Yousef, Tracey Kevin J, Pavlov Valentin A
神经科学
炎症
发表日期：2015
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Experimentally validated novel inhibitors of Helicobacter pylori phosphopantetheine adenylyltransferase discovered by virtual high-throughput screening

通过虚拟高通量筛选发现经实验验证的幽门螺杆菌磷酸泛酰巯基乙胺腺苷酸转移酶新型抑制剂

期刊:PLoS One
影响因子:2.9
doi:10.1371/journal.pone.0074271
Chao-Sheng Cheng, Kai-Fan Jia, Ting Chen, Shun-Ya Chang, Ming-Shen Lin, Hsien-Sheng Yin
微生物学
发表日期：2013
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Macrophage migration inhibitory factor mediates hypoxia-induced pulmonary hypertension

巨噬细胞迁移抑制因子介导缺氧诱导的肺动脉高压

期刊:Molecular Medicine
影响因子:6.4
doi:10.2119/molmed.2011.00094
Zhang, Yinzhong; Talwar, Arunabh; Tsang, Donna; Bruchfeld, Annette; Sadoughi, Ali; Hu, Maowen; Omonuwa, Kennedy; Cheng, Kai Fan; Al-Abed, Yousef; Miller, Edmund J
巨噬细胞
巨噬细胞
心血管
肺动脉高压
细胞生物学
免疫/内分泌
发表日期：2012
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Generation of a unique small molecule peptidomimetic that neutralizes lupus autoantibody activity.

生成一种独特的小分子肽模拟物，可中和狼疮自身抗体活性

期刊:Proceedings of the National Academy of Sciences of the United States of America
影响因子:9.1
doi:10.1073/pnas.1103555108
Bloom Ona, Cheng Kai Fan, He Mingzhu, Papatheodorou Angelos, Volpe Bruce T, Diamond Betty, Al-Abed Yousef
免疫/内分泌
发表日期：2011
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